Cost-effectiveness of a programme to address sedentary behaviour in older adults : Results from the SITLESS RCT
Deidda, Manuela (Health Economics and Health Technology Assessment (HEHTA). Institute of Health and Wellbeing (IHW). University of Glasgow)
Coll-Planas, Laura (Universitat Autònoma de Barcelona. Fundació Salut i Envelliment)
Tully, Marl A. (University of Ulster)
Giné-Garriga, Maria (Facultat de Psicologia i Ciències de l'Educació i de l'Esport Blanquerna)
Kee, Frank (UKCRC Centre of Excellence for Public Health (NI). Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queen's University Belfast)
Roqué i Figuls, Marta (Institut d'Investigació Biomèdica Sant Pau)
Blackburn, Nicole E.. (University of Ulster)
Guerra-Balic, Míriam (Facultat de Psicologia i Ciències de l'Educació i de l'Esport Blanquerna)
Rothenbacher, Dietrich (Institute of Epidemiology and Medical Biometry. Ulm University)
Dallmeier, Dhayana (Agaplesion Bethesda Hospital. Geriatric Research Unit. Ulm University)
Caserotti, Paolo (Department of Sports Science and Clinical Biomechanics. Syddansk Universitet)
Skjødt, Mathias (Department of Sports Science and Clinical Biomechanics. Syddansk Universitet)
McIntosh, Emma (Health Economics and Health Technology Assessment (HEHTA). Institute of Health and Wellbeing (IHW). University of Glasgow)
Universitat Autònoma de Barcelona

Data:	2022
Resum:	Background: This study details the within-trial economic evaluation and long-term economic model of SITLESS, a multi-country, three-armed randomized controlled trial comparing a combined intervention of exercise referral schemes (ERS) enhanced by self-management strategies (SMS) against ERS alone and usual care (UC). Methods: A cost-utility analysis, conducted from the base-case perspective of the National Health Service and personal and social services, estimated the incremental cost per incremental quality-adjusted life year (QALY) and years in full capability (YFC). A secondary analysis combined the costs with a broad set of outcomes within a cost-consequence framework, from a societal perspective. A Markov-type decision-analytic model was developed to project short-term changes in physical activity to long-term outcomes and costs, over a 5- and 15-year time horizon. Results: The results of the within-trial analysis show that SMS+ERS is highly likely to be cost-effective compared to ERS alone (ICER €4270/QALY), but not compared to UC. Participants allocated to the SMS+ERS group also showed an improvement in YFC compared to ERS alone and UC. The long-term analysis revealed that SMS+ERS is likely to be a cost-effective option compared to ERS and UC over a 5-year, but not with a 15-year horizon, being then dominated by ERS alone. Conclusion: This research provides new evidence that SMS is a cost-effective add-on to ERS strategies. This economic evaluation informs the case for further, cost-effective, refinement of lifestyle change programmes targeted to older adults, with the aim of ultimately reducing the impact of non-communicable diseases in this population.
Ajuts:	European Commission. Horizon 2020 634270
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Aged ; Cost-Benefit Analysis ; Exercise ; Humans ; Quality-Adjusted Life Years ; Sedentary Behavior ; State Medicine
Publicat a:	European journal of public health, Vol. 32 Núm. 3 (january 2022) , p. 415-421, ISSN 1464-360X

DOI: 10.1093/eurpub/ckac017
PMID: 35426903

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