Small renal masses in kidney transplantation : Overview of clinical impact and management in donors and recipients
Piana, Alberto (Fundació Puigvert)
Andras, Iulia (Iuliu Hatieganu University of Medicine and Pharmacy and Municipal Hospital)
Diana, Pietro (Fundació Puigvert)
Verri, Paolo (Fundació Puigvert)
Gallioli, Andrea (Fundació Puigvert)
Campi, Riccardo (Università degli Studi di Firenze)
Prudhomme, Thomas (Toulouse University Hospital)
Hevia, Vital (Hospital Universitario Ramón y Cajal (Madrid))
Boissier, Romain (Aix-Marseille université)
Breda, Alberto (Fundació Puigvert)
Territo, Angelo (Fundació Puigvert)
Universitat Autònoma de Barcelona

Date:	2022
Abstract:	Kidney transplantation is the best replacement treatment for the end-stage renal disease. Currently, the imbalance between the number of patients on a transplant list and the number of organs available constitutes the crucial limitation of this approach. To expand the pool of organs amenable for transplantation, kidneys coming from older patients have been employed; however, the combination of these organs in conjunction with the chronic use of immunosuppressive therapy increases the risk of incidence of graft small renal tumors. This narrative review aims to provide the state of the art on the clinical impact and management of incidentally diagnosed small renal tumors in either donors or recipients. According to the most updated evidence, the use of grafts with a small renal mass, after bench table tumor excision, may be considered a safe option for high-risk patients in hemodialysis. On the other hand, an early small renal mass finding on periodic ultrasound-evaluation in the graft should allow to perform a conservative treatment in order to preserve renal function. Finally, in case of a renal tumor in native kidney, a radical nephrectomy is usually recommended.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Small renal mass ; Renal cancer ; Kidney transplantation ; Nephron-sparing treatment
Published in:	Asian Journal of Urology, Vol. 9 (june 2022) , p. 208-214, ISSN 2214-3890

DOI: 10.1016/j.ajur.2022.06.001
PMID: 36035353

7 p, 445.9 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles