Cell death as a defense strategy against pathogens in plants and animals
Salguero Linares, Jose (Centre de Recerca en Agrigenòmica)
Sánchez Coll, Núria (Centre de Recerca en Agrigenòmica)

Date:	2023
Abstract:	Eukaryotes are endowed with sophisticated innate immune systems to recognize non-self and halt pathogen proliferation. Activation of cell death at the site of attempted pathogen ingress is a common strategy used by plants and animals to restrict pathogen proliferation and trigger immune responses in the surrounding tissues. As such, immunogenic cell death shares several features in both plants and animals that will be discussed in this article, namely: (i) it is triggered by activation of NLR immune receptors-often through oligomerization; (ii) it results in disruption of the plasma membrane (PM)/endomembrane integrity driving an imbalance in ion fluxes; and (iii) it results in the release of signaling molecules from dying cells.
Grants:	Agencia Estatal de Investigación PID2019-108595RB-I00 Agencia Estatal de Investigación BES-2017-080210 Agencia Estatal de Investigación CEX2019-000917
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	PLOS pathogens, Vol. 19 (April 2023) , art. e1011253, ISSN 1553-7374

DOI: 10.1371/journal.ppat.1011253
PMID: 37023043

9 p, 872.1 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles