Abstract: |
The purpose of this study was to identify clinical, analytical, and sociodemographic variables associated with the need for hospital admission in people over 50 years infected with SARS-CoV-2 and to assess whether diabetes mellitus conditions the risk of hospitalization. A multicenter case-control study analyzing electronic medical records in patients with COVID-19 from 1 March 2020 to 30 April 2021 was conducted. We included 790 patients: 295 cases admitted to the hospital and 495 controls. Under half (n = 386, 48. 8%) were women, and 8. 5% were active smokers. The main comorbidities were hypertension (50. 5%), dyslipidemia, obesity, and diabetes (37. 5%). Multivariable logistic regression showed that hospital admission was associated with age above 65 years (OR from 2. 45 to 3. 89, ascending with age group); male sex (OR 2. 15, 95% CI 1. 47-3. 15), fever (OR 4. 31, 95% CI 2. 87-6. 47), cough (OR 1. 89, 95% CI 1. 28-2. 80), asthenia/malaise (OR 2. 04, 95% CI 1. 38-3. 03), dyspnea (4. 69, 95% CI 3. 00-7. 33), confusion (OR 8. 87, 95% CI 1. 68-46. 78), and a history of hypertension (OR 1. 61, 95% CI 1. 08-2. 41) or immunosuppression (OR 4. 97, 95% CI 1. 45-17. 09). Diabetes was not associated with increased risk of hospital admission (OR 1. 18, 95% CI 0. 80-1. 72; p = 0. 38). Diabetes did not increase the risk of hospital admission in people over 50 years old, but advanced age, male sex, fever, cough, asthenia, dyspnea/confusion, and hypertension or immunosuppression did. |