Epidemiology of uterine myomas and clinical practice in Spain : An observational study
Monleón, J. (Hospital Universitari i Politècnic La Fe (València))
Cañete, M.L. (Complejo Hospitalario de Toledo)
Caballero, V. (Hospital Universitario Virgen de Valme (Sevilla, Andalusia))
del Campo, M. (Centro Médico Teknon - Grupo Hospitalario Quirón)
Doménech, A. (Gedeon Richter Ibérica)
Losada, M.Á. (Gedeon Richter Ibérica)
Calaf Alsina, Joaquim (Institut d'Investigació Biomèdica Sant Pau)
Montero, Ana Isabel (Hospital Universitari Vall d'Hebron)
Ripero, Maider (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Universitat Autònoma de Barcelona

Fecha:	2018
Resumen:	Characterization of the clinical features of symptomatic uterine myomas in Spanish women visiting the gynaecologist, including impact on quality of life and possible risk factors, description of main therapeutic approaches, and evaluation of symptom and quality of life progression 6 months after inclusion in the study. This was an observational, epidemiological, non-interventional, multicentre study performed between June 2015 and March 2016. Data were collected at baseline and follow-up visits 6 months apart from women with a diagnosis of uterine myomas and visiting a participating gynaecologist in outpatient units of private clinics or public hospitals in Spain. Data consisted of a gynaecological clinical inspection, an interview with open questions to the patients, and self-administered generic questionnaires. The main outcome measures were socio-demographic data, clinical history, myoma clinical features, symptomatology, data on surgical choices, patient satisfaction, and risk factors associated to myomas. Data were collected from 569 patients (1,022 myomas) at 56 hospitals and private gynaecological offices in Spain. Most patients (85%) presented between 1 and 3 myomas, predominantly intramural and subserosal. Most common symptoms reported heavy menstrual bleeding and pelvic pain, and the mean (±SD) symptom severity score in the UFS-QoL questionnaire (range 0-100) was 50. 89 ± 20. 85. Up to 60. 5% of patients had an indication of surgery (55. 8% myomectomies, 40. 4% hysterectomies) to treat their uterine myomas and 39. 5% followed other therapies, mainly pharmacological. After six months of treatment, all patients had experienced significant reduction in symptoms and improvement of quality of life. The most frequent symptoms reported by women diagnosed with uterine myomas were heavy menstrual bleeding, pelvic or abdominal pain and dysmenorrhea; QoL was impaired reflecting high symptom distress. We found that surgery was the main therapeutic approach to manage uterine myomas in Spain. Both surgical and non-surgical treatments achieve relevant improvements in symptom severity and quality of life.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Abnormal uterine bleeding ; Hysterectomy ; Myomectomy ; Uterine myomas
Publicado en:	European Journal of Obstetrics and Gynecology and Reproductive Biology, Vol. 226 (july 2018) , p. 59-65, ISSN 1872-7654

DOI: 10.1016/j.ejogrb.2018.05.026

7 p, 706.3 KB

El registro aparece en las colecciones:
Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut de Recerca Sant Pau
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