Social inequalities in quality of life in a cohort of women diagnosed with breast cancer in Barcelona (DAMA Cohort)
Graells-Sans, A. (Campus Docent Sant Joan de Déu)
Serral, Gemma (Institut d'Investigació Biomèdica Sant Pau)
Puigpinós i Riera, Rosa (Institut d'Investigació Biomèdica Sant Pau)
Bargalló, Xavier Aguilar (Hospital Clínic i Provincial de Barcelona)
Espinosa-Bravo, Martín (Hospital Universitari Vall d'Hebron)
Grau, Jaume (Hospital Clínic i Provincial de Barcelona)
Macià, Francesc (Institut Hospital del Mar d'Investigacions Mèdiques)
Quintana Ruiz, Maria Jesús (Institut d'Investigació Biomèdica Sant Pau)
Sala, Maria (Institut Hospital del Mar d'Investigacions Mèdiques)
Universitat Autònoma de Barcelona

Data:	2018
Resum:	Breast cancer is a challenge for women's health-related quality of life (QoL), compromising their physical health and emotional well-being. QoL is equally distributed among different social groups. The aim of this study to analyze the impact of clinical characteristics and social determinants of health on the QoL of a cohort of women diagnosed and/or treated for breast cancer between 2003 and 2013 in one of the main hospitals in Barcelona's public health network. We performed a descriptive cross-sectional study in a cohort of 2235 women with various stages of breast cancer at different stages of their disease. Data were obtained using questionnaires QLQ-C30 and QLQ-BR23 from the European Organization for Research and Treatment of Cancer (EORTC), which include a set of functional and symptomatic scales. We conducted descriptive and bivariate analysis using the Chi-Square test and adjusted for relevant variables using logistic regression. The dependent variables were the functional scales of QoL and the independent variables were sociodemographic and clinical variables. We observed significant differences for most QoL functions. Women from the most disadvantaged class, those in social isolation, or those who had suffered relapses showed the poorest results for most of the function scales. In contrast, age had differential effects depending on the function studied. The QoL of women diagnosed with breast cancer is closely linked to both their social and economic status, and to their stage of disease progression. It is necessary to explore interventions that focus on the social determinants of health in order to mitigate their effects on breast cancer survivors' QoL.
Ajuts:	Ministerio de Economía y Competitividad PI13/01977
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Breast cancer ; Cohort of women with breast cancer ; Quality of life ; Social inequalities
Publicat a:	Cancer Epidemiology, Vol. 54 (june 2018) , p. 38-47, ISSN 1877-783X

DOI: 10.1016/j.canep.2018.03.007
PMID: 29573623

10 p, 690.6 KB

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