| Resum: |
The phenotype of patients affected by COVID-19 disease changed between the waves of the pandemic. We assessed the prevalence of oropharyngeal dysphagia (OD), malnutrition (MN), and mortality between the first three waves of COVID-19 patients in a general hospital. A prospective observational study between April 2020-May 2021. Clinical assessment for OD was made with the volume-viscosity swallowing test; nutritional assessment was performed consistent with GLIM criteria. A multimodal intervention was implemented in the second and third wave, including (a) texturized diets-fork mashable (1900 kcal + 90 g protein) or pureed (1700 kcal + 75 g protein), (b) oral nutritional supplements (500-600 kcal + 25-30 g protein), and (c) fluid thickening (250 mPa·s or 800 mPa·s). We included 205 patients (69. 3 ± 17. 6 years) in the 1st, 200 (66. 4 ± 17. 5 years) in the 2nd, and 200 (72. 0 ± 16. 3 years;) in the 3rd wave (p = 0. 004). On admission, prevalence of OD was 51. 7%, 31. 3% and 35. 1%, and MN, 45. 9%, 36. 8% and 34. 7%, respectively; mortality was 10. 7%, 13. 6% and 19. 1%. OD was independently associated with age, delirium, and MN; MN, with age, OD, diarrhea and ICU admission; mortality, with age, OD and MN. Prevalence of OD, MN and mortality was very high among COVID-19 patients. OD was independently associated with MN and mortality. An early and proactive multimodal nutritional intervention improved patients' nutritional status. |