The role of basal insulins in the treatment of people with type 2 diabetes and chronic kidney disease : A narrative review
Sloan, Lance (University of Texas Medical Branch)
Cheng, Alice Y.Y. (University of Toronto)
Escalada, Javier (Instituto de Investigación Sanitaria de Navarra)
Haluzík, Martin (Institute for Clinical and Experimental Medicine)
Mauricio, Didac (Institut de Recerca Sant Pau)
Universitat Autònoma de Barcelona

Date:	2024
Abstract:	The majority of cases of chronic kidney disease (CKD) worldwide are driven by the presence of type 2 diabetes (T2D), resulting in an increase in CKD rates over the past few decades. The existence of CKD alongside diabetes is associated with increased burden of cardiovascular disease and increased risk of death. Optimal glycaemic control is essential to prevent progression of CKD, but achieving glycaemic targets in people with CKD and diabetes can be challenging because of increased risk of hypoglycaemia and limitations on glucose-lowering therapeutic options. This review considers the challenges in management of T2D in people with impaired kidney function and assesses evidence for use of basal insulin analogues in people with CKD.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Subject:	Basal insulin ; Diabetes complications ; Diabetic nephropathy ; Hypoglycaemia ; Type 2 diabetes
Published in:	Diabetes, Obesity and Metabolism, Vol. 26 Núm. 4 (april 2024) , p. 1157-1170, ISSN 1463-1326

DOI: 10.1111/dom.15425
PMID: 38225217

14 p, 1023.2 KB

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Articles > Research articles
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