Aerobic exercise and cognitive function in chronic severe traumatic brain injury survivors : a within-subject A-B-A intervention study
Pérez López, Lidia (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Coll Andreu, Margalida (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Torras Garcia, Meritxell (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Font-Farré, Manel (Universitat Ramon Llull. Departament de Psicologia)
Oviedo, Guillermo R. (Universitat Ramon Llull. Departament de Psicologia)
Capdevila Ortís, Lluís (Universitat Autònoma de Barcelona. Instituto de Investigación del Deporte)
Guerra-Balic, Myriam (Universitat Ramon Llull. Departament de Psicologia)
Portell Cortés, Isabel (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Costa Miserachs, David (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Morris, Timothy P (Northeastern University. Department of Physics)

Data:	2024
Descripció:	10 pàg.
Resum:	BACKGROUND: Following acute and sub-acute rehabilitation from severe traumatic brain injury (TBI), minimal to no efficacious interventions to treat ongoing cognitive deficits are available. Aerobic exercise is a non-invasive behavioral intervention with promise to treat cognitive deficits in TBI populations. METHODS: Six individuals, aged 24-62 years, with chronic (> 8 months since injury) severe (Glasgow Coma Scale of 3-8) TBI were recruited from two outpatient rehabilitation centers. In an A-B-A study design, 20-weeks of supervised aerobic exercise interventions were delivered three times per week (phase B) in addition to participants typical rehabilitation schedules (phases A). The effect of phase B was tested on a trail making test part B (primary outcome measure of executive function) as well as objective daily physical activity (PA), using both group level (linear mixed effect models) and single subject statistics. RESULTS: Five of six participants increased trail-making test part B by more than 10% pre-to-post phase B, with three of six making a clinically meaningful improvement (+ 1SD in normative scores). A significant main effect of time was seen with significant improvement in trail-making test part B pre-to-post exercise (phase B). No significant effects in other planned comparisons were found. Statistically significant increases in daily moderate-to-vigorous PA were also seen during phase B compared to phase A with three of six individuals making a significant behaviour change. CONCLUSIONS: The addition of supervised aerobic exercise to typical rehabilitation strategies in chronic survivors of severe TBI can improve executive set shifting abilities and increase voluntary daily PA levels.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Traumatic brain injury ; Cognitive function ; Physical exercise ; Physical activity
Publicat a:	BMC Sports Science, Medicine and Rehabilitation, Vol. 16 Núm. 1 (september 2024) , ISSN 2052-1847

DOI: 10.1186/s13102-024-00993-4
PMID: 39334396

10 p, 1.1 MB

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