Cost-effectiveness of active tuberculosis screening among high-risk populations in low tuberculosis incidence countries : a systematic review, 2008 to 2023
Gogichadze, Nino (Universitat Autònoma de Barcelona)
Sagrera, Arnau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Vicente, José Ángel (Universitat Pompeu Fabra)
Millet, Joan Pau (Institut de Recerca Sant Pau)
López-Seguí, Francesc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Vilaplana Massaguer, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)

Date:	2024
Abstract:	Background: In countries with a low TB incidence (≤ 10 cases/100,000 population), active pulmonary tuberculosis (PTB) mostly affects vulnerable populations with limited access to healthcare. Thus, passive case-finding systems may not be successful in detecting and treating cases and preventing further transmission. Active and cost-effective search strategies can overcome this problem. Aim: We aimed to review the evidence on the cost-effectiveness (C-E) of active PTB screening programmes among high-risk populations in low TB incidence countries. Methods: We performed a systematic literature search covering 2008-2023 on PubMed, Embase, Center for Reviews and Dissemination, including Database of Abstracts of Reviews of Effects (DARE), National Health Services Economic Evaluation Database (NHS EED), Global Index Medicus and Cochrane Central Register of Controlled Trials CENTRAL). Results: We retrieved 6,318 articles and included nine in this review. All included studies had an active case-finding approach and used chest X-ray, tuberculin skin test, interferon-gamma release assay and a symptoms questionnaire for screening. The results indicate that screening immigrants from countries with a TB incidence.
Grants:	Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-0092 European Commission 847762
Note:	This work was supported by the Catalan Government via 2021 SGR-00920 and received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement number. 847762.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Cost-Benefit Analysis ; Humans ; Incidence ; Mass Screening ; Tuberculin Test ; Tuberculosis ; Tuberculosis, Pulmonary
Published in:	Eurosurveillance, Vol. 29 Núm. 12 (21 2024) , p. 2300614, ISSN 1560-7917

DOI: 10.2807/1560-7917.ES.2024.29.12.2300614
PMID: 38516785

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles