New oral anticoagulants vs vitamin K antagonists : Benefits for health-related quality of life in patients with atrial fibrillation
Alegret i Colomé, Josep Maria (Universitat Rovira i Virgili)
Viñolas, Xavier (Institut d'Investigació Biomèdica Sant Pau)
Arias, Miguel A. (Hospital Virgen de la Salud (Toledo))
Martínez-Rubio, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Rebollo, Pablo (LA-SER Outcomes)
Ràfols, Carles (Bayer HealthCare (Barcelona))
Martínez-Sande, José L. (Hospital Clínico)
Universitat Autònoma de Barcelona. Departament de Medicina

Date:	2014
Abstract:	New oral anticoagulants (NOAC) have demonstrated their efficacy as an alternative to vitamin K antagonists (VKA) in the prophylaxis of cardioembolic events in patients with atrial fibrillation (AF). However, evidence on the benefits of NOAC in health-related quality of life (HRQoL) is lacking. We evaluated changes in HRQoL related to oral anticoagulation therapy employing a specific questionnaire in a cohort of 416 patients with AF undergoing electrical cardioversion. In terms of HRQoL, we observed a progressive adaptation to treatment with VKA; satisfaction with NOAC remained constant. Older age, higher left ventricular ejection fraction and NOAC were associated with better HRQoL. © Ivyspring International Publisher.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Dabigatran ; Health-related quality of life ; New oral anticoagulants ; Ribaroxaban ; Vitamin K antagonists
Published in:	International Journal of Medical Sciences, Vol. 11 Núm. 7 (january 2014) , p. 680-684, ISSN 1449-1907

DOI: 10.7150/ijms.8916
PMID: 24843316

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles