DisProt in 2022 : improved quality and accessibility of protein intrinsic disorder annotation
Quaglia, Federica (University of Padova)
Mészáros, Bálint (European Molecular Biology Laboratory Hamburg)
Salladini, Edoardo (University of Padova)
Hatos, András (University of Padova)
Pancsa, Rita (Eötvös Loránd Research Network)
Chemes, Lucía Beatriz (National University of General San Martín)
Pajkos, Mátyás (Eötvös Loránd University)
Lazar, Tamas (Vrije Universiteit Brussel)
Peña Díaz, Samuel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Santos, Jaime (Universitat Autònoma de Barcelona)
Ács, Veronika (Eötvös Loránd Research Network)
Farahi, Nazanin (Vrije Universiteit Brussel)
Fichó, Erzsébet (Eötvös Loránd Research Network. Cytocast Kft.)
Aspromonte, Maria Cristina (University of Padova)
Bassot, Claudio (Science for Life Laboratory)
Chasapi, Anastasia (Centre for Research and Technology Hellas (Tessalònica, Grècia))
Davey, Norman E. (The Institute of Cancer Research)
Davidović, Radoslav (University of Belgrade)
Dobson, Laszlo (European Molecular Biology Laboratory Hamburg)
Elofsson, Arne (Science for Life Laboratory)
Erdős, Gábor (Eötvös Loránd University)
Gaudet, Pascale (Swiss Institute of Bioinformatics)
Giglio, Michelle (University of Maryland School of Medicine)
Glavina, Juliana (National University of General San Martín)
Iserte, Javier (Fundación Instituto Leloir (Buenos Aires, Argentina))
Iglesias, Valentin (Universitat Autònoma de Barcelona)
Kálmán, Zsófia (Pázmány Peter Catholic University)
Lambrughi, Matteo (Danish Cancer Society Research Center)
Leonardi, Emanuela (University of Padova)
Longhi, Sonia (Aix-Marseille University)
Macedo-Ribeiro, Sandra (University of Porto)
Maiani, Emiliano (Danish Cancer Society Research Center)
Marchetti, Julia (National University of Quilmes)
Marino-Buslje, Cristina (Fundación Instituto Leloir (Buenos Aires, Argentina))
Mészáros, Attila (Vrije Universiteit Brussel)
Monzon, Alexander Miguel (University of Padova)
Minervini, Giovanni (University of Padova)
Nadendla, Suvarna (University of Maryland School of Medicine)
Nilsson, Juliet F. (Aix-Marseille University)
Novotný, Marian (Charles University)
Ouzounis, Christos (Centre for Research and Technology Hellas (Tessalònica, Grècia))
Palopoli, Nicolás (National University of Quilmes)
Papaleo, Elena (Danish Cancer Society Research Center)
Pereira, Pedro José Barbosa (Science for Life Laboratory)
Pozzati, Gabriele (University of Porto)
Promponas, Vasilis J. (University of Cyprus)
Pujols, Jordi (Universitat Autònoma de Barcelona)
Rocha, Alma Carolina Sanchez (Charles University)
Salas, Martin (National University of Quilmes)
Sawicki, Luciana Rodriguez (National University of Quilmes)
Schad, Eva (Eötvös Loránd University)
Shenoy, Aditi (Science for Life Laboratory)
Szaniszló, Tamás (Eötvös Loránd University)
Tsirigos, Konstantinos D. (European Molecular Biology Laboratory Hamburg)
Veljkovic, Nevena (University of Belgrade)
Parisi, Gustavo (National University of Quilmes)
Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Dosztányi, Zsuzsanna (Eötvös Loránd University)
Tompa, Peter (Eötvös Loránd Research Network)
Tosatto, Silvio (University of Padova)
Piovesan, Damiano (University of Padova)

Data:	2022
Resum:	The Database of Intrinsically Disordered Proteins (DisProt, URL: ) is the major repository of manually curated annotations of intrinsically disordered proteins and regions from the literature. We report here recent updates of DisProt version 9, including a restyled web interface, refactored Intrinsically Disordered Proteins Ontology (IDPO), improvements in the curation process and significant content growth of around 30%. Higher quality and consistency of annotations is provided by a newly implemented reviewing process and training of curators. The increased curation capacity is fostered by the integration of DisProt with APICURON, a dedicated resource for the proper attribution and recognition of biocuration efforts. Better interoperability is provided through the adoption of the Minimum Information About Disorder (MIADE) standard, an active collaboration with the Gene Ontology (GO) and Evidence and Conclusion Ontology (ECO) consortia and the support of the ELIXIR infrastructure.
Ajuts:	European Commission 778247 European Commission 952334 European Commission 842490 Ministerio de Ciencia e Innovación FPU17/01157 European Commission 101028908
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	Nucleic acids research, Vol. 50, Issue D1 (January 2022) , p. D480-D487, ISSN 1362-4962

DOI: 10.1093/nar/gkab1082
PMID: 34850135

8 p, 2.0 MB

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