Exploring the Effectiveness of Self-Management Interventions in Type 2 Diabetes : A Systematic Review and Network Meta-Analysis
Tsokani, Sofia (Cochrane CET)
Seitidis, Georgios (University of Ioannina (Grècia))
Christogiannis, Christos (University of Ioannina (Grècia))
Kontouli, Katerina Maria (University of Ioannina (Grècia))
Nikolakopoulos, Stavros (University of Ioannina (Grècia))
Zevgiti, Stella (University of Ioannina (Grècia))
Orrego, Carola (Universitat Autònoma de Barcelona)
Ballester, Marta (Universitat Autònoma de Barcelona)
Suñol Sala, Rosa (Universitat Autònoma de Barcelona)
Heijmans, Monique J. W. M. (Netherlands Institute of Health Services Research (Països Baixos))
Poortvliet, Rune (Netherlands Institute of Health Services Research (Països Baixos))
Van der Gaag, Marieke (Netherlands Institute of Health Services Research (Països Baixos))
Alonso-Coello, Pablo (Institut de Recerca Sant Pau)
Canelo Aybar, Carlos Gilberto (Institut de Recerca Sant Pau)
Beltran, Jessica (Institut de Recerca Sant Pau)
González González, Ana Isabel (Universitat Autònoma de Barcelona)
de Graaf, Gimon (Erasmus University (Països Baixos))
Veroniki, Areti Angeliki (University of Toronto)
Mavridis, Dimitris (University of Ioannina (Grècia))

Data:	2024
Resum:	Background: Chronic diseases are a leading cause of global morbidity and mortality. In response to this challenge, self-management interventions (SMIs) have emerged as an essential tool in improving patient outcomes. However, the diverse and complex nature of SMIs pose significant challenges in measuring their effectiveness. This work aims to investigate the comparative effectiveness of SMIs on Type 2 diabetes mellitus (T2DM) outcomes. Methods: A rigorous analytical framework was employed to assess the relative effectiveness of different SMIs, encompassing both pairwise and network meta-analysis (NMA), as well as component network meta-analysis (CNMA). Various outcomes were considered, including glycated hemoglobin (HbA1c) control, body mass index (BMI) reduction and low-density lipoprotein (LDL) cholesterol. Visualization tools were also utilized to enhance the interpretation of results. Results: SMIs were found promising in improving clinical outcomes and patient-reported measures. However, considerable heterogeneity and inconsistency across studies challenged the validity of NMA results. CNMA along with various visualization tools offered insights into the contributions of individual SMI components, highlighting the complexity of these interventions. Discussion/Conclusions: SMIs represent a valuable approach to managing chronic conditions, but their effectiveness is context-dependent. Further research is needed to elucidate the contextual factors influencing SMI outcomes. This work contributes to a comprehensive understanding of SMIs' role in T2DM management, aiming to aid decision-makers, clinicians, and patients in selecting tailored interventions.
Ajuts:	European Commission 754936
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Matèria:	Component network meta-analysis ; Network meta-analysis ; Self-management interventions ; Type 2 diabetes
Publicat a:	Healthcare, Vol. 12 Núm. 1 (january 2024) , p. 27, ISSN 2227-9032

DOI: 10.3390/healthcare12010027
PMID: 38200933

21 p, 9.3 MB

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