A Study of the Relationship Between Objective Tests to Diagnose Erectile Dysfunction and Markers of Cardiovascular Disease
De Rocco Ponce, Maurizio (Institut de Recerca Sant Pau)
Quintian Schwieters, Claudia Fabiana (Institut de Recerca Sant Pau)
Meziere, Juliette (San Luigi Gonzaga University Hospital)
Sánchez-Curbelo, Josvany (Institut de Recerca Sant Pau)
Abad Carratalá, Guillem (Hospital Provincial de Castelló)
Troka, Eden (University of Padua)
Bassas, Lluís (Institut de Recerca Sant Pau)
Ruiz-Castañé, Eduardo (Institut de Recerca Sant Pau)
Martinez Barcina, Maria José (Institut de Recerca Sant Pau)
Rajmil, Osvaldo (Institut de Recerca Sant Pau)

Data:	2024
Resum:	Background: Erectile dysfunction (ED) can stem from various organic and functional causes but is often linked to vascular health and cardiovascular disease. Limited data exist on how cardiovascular disease markers correlate with objective ED tests like the Nocturnal Penile Tumescence and Rigidity (NPTR) test and Penile Color Doppler Ultrasound (PCDU). Methods : A prospective observational study was performed, and 58 men with ED were assessed using the International Index of Erectile Function-15 (IIEF-15), NPTR test, and PCDU. Peripheral vascular health was evaluated through carotid intima-media thickness (cIMT) and brachial flow-mediated dilation (FMD). Results: Out of the participants, 44 had normal NPTR results, while 14 had abnormal results. The group with abnormal NPTR results was significantly older and had higher rates of hypertension and diabetes. Although the IIEF-15 scores were similar between the two groups, those with abnormal NPTR results had a lower peak systolic velocity (PSV) and a higher prevalence of impaired PSV. Correlations between the IIEF, NPTR, PCDU, and peripheral vascular markers lost significance after the age adjustment. Conclusions: This study suggests that abnormal NPTR results, combined with cardiovascular risk factors, may signal vascular ED and generalized vasculopathy, highlighting the need for cardiovascular assessment. An accurate ED diagnosis should integrate clinical evaluation with multiple tests while considering aging as a key risk factor.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Erectile dysfunction ; Penile Color Doppler Ultrasound ; Nocturnal Penile Tumescence and Rigidity test
Publicat a:	Journal of clinical medicine, Vol. 13, Núm. 21 (October 2024) , ISSN 2077-0383

DOI: 10.3390/jcm13216321
PMID: 39518460

9 p, 253.1 KB

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