Acute Myeloid Leukemia as a Trigger for Hemolytic-Uremic Syndrome
El Bachouti, J. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Domínguez-Guasch, A. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Arce, Y. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Oñate, Guadalupe (Institut de Recerca Sant Pau)
Marco, H. (Institut de Recerca Sant Pau)
Díaz Encarnación, Montserrat Mercedes (Institut de Recerca Sant Pau)
Guirado, Luis (Institut de Recerca Sant Pau)
Torra Balcells, Roser (Institut de Recerca Sant Pau)
Barros, Xoana (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Universitat Autònoma de Barcelona

Date:	2024
Abstract:	Acute myeloid leukemia (AML) has not been identified as a cause of secondary hemolytic-uremic syndrome (HUS). This case report describes a woman who developed severe HUS at the time of AML diagnosis and responded favorably to initial treatment with eculizumab, which stabilized her condition and allowed for treatment of the AML. After one year, with stable renal function and genetic studies reported as normal, eculizumab was successfully discontinued. The prompt use of eculizumab was critical to the patient's survival and improvement in renal function, highlighting the efficacy of early eculizumab treatment in secondary HUS.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Acute myeloid leukemia ; Eculizumab ; Hemolytic uremic syndrome
Published in:	Journal of clinical medicine, Vol. 13 Núm. 21 (november 2024) , p. 6468, ISSN 2077-0383

DOI: 10.3390/jcm13216468
PMID: 39518607

6 p, 1.0 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles