Web of Science: 30 cites, Scopus: 32 cites, Google Scholar: cites,
MXenes in healthcare : synthesis, fundamentals and applications
Babar, Zaheer Ud Din (Institut Català de Nanociència i Nanotecnologia)
Iannotti, Vincenzo (University of Naples Federico II. Department of Physics "E. Pancini")
Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia)
Zaheer, Ayesha (University of Naples Federico II.Department of Physics "E. Pancini")
Velotta, Raffaele (University of Naples Federico II. Department of Physics "E. Pancini")
Della Ventura, Bartolomeo (University of Naples Federico II. Department of Physics "E. Pancini")
Álvarez Diduk, Ruslan (Institut Català de Nanociència i Nanotecnologia)
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)

Data: 2025
Resum: Since their discovery over a decade ago, MXenes have transformed the field of "materials for healthcare", stimulating growing interest in their healthcare-related applications. These developments have also driven significant advancements in MXenes' synthesis. This review systematically examines the synthesis of MXenes and their applications in sensing and biomedical fields, underscoring their pivotal role in addressing critical challenges in modern healthcare. We describe the experimental synthesis of MXenes by combining appropriate laboratory modules with the mechanistic principles underlying each synthesis step. In addition, we provide extensive details on the experimental parameters, critical considerations, and essential instructions for successful laboratory synthesis. Various healthcare applications including sensing, biomedical imaging, synergistic therapies, regenerative medicine, and wearable devices have been explored. We further highlight the emerging trends of MXenes, viz. , their role as nanovehicles for drug delivery, vectors for gene therapy, and tools for immune profiling. By identifying the important parameters that define the utility of MXenes in biomedical applications, this review outlines strategies to regulate their biomedical profile, thereby serving as a valuable guide to design MXenes with application-specific properties. The final section integrates experimental research with theoretical studies to provide a comprehensive understanding of the field. It examines the role of emerging technologies, such as artificial intelligence (AI) and machine learning (ML), in accelerating material discovery, structure-property optimization, and automation. Complemented by detailed supplementary information on synthesis, stability, biocompatibility, environmental impact, and theoretical insights, this review offers a profound knowledge base for understanding this diverse family of 2D materials. Finally, we compared the potential of MXenes with that of other 2D materials to underscore the existing challenges and prioritize interdisciplinary collaboration. By synthesizing key studies from its discovery to current trends (especially from 2018 onward), this review provides a cohesive assessment of MXene synthesis with theoretical foundations and their prospects in the healthcare sector.
Ajuts: European Commission 101120706
Agencia Estatal de Investigación CEX2021-001214-S
Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-01464
Agencia Estatal de Investigación PID2021-124795NB-I00
Drets: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Llengua: Anglès
Document: Article de revisió ; recerca ; Versió publicada
Matèria: Biomedical fields ; Biomedical imaging ; Critical challenges ; Experimental parameters ; Health care application ; Laboratory module ; Mechanistics ; Regenerative medicine ; Sensing fields ; Wearable devices ; Artificial Intelligence ; Delivery of Health Care ; Drug Delivery Systems ; Humans
Publicat a: Chemical Society Reviews, Vol. 54, Issue 7 (April 2025) , p. 3387-3440, ISSN 1460-4744

DOI: 10.1039/d3cs01024d


54 p, 4.1 MB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències > Institut Català de Nanociència i Nanotecnologia (ICN2)
Articles > Articles de recerca
Articles > Articles publicats

 Registre creat el 2025-05-16, darrera modificació el 2025-05-21



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