Probiotic significance of Lactobacillus strains : a comprehensive review on health impacts, research gaps, and future prospects
Shah, Abdul Bari 
(Seoul National University. Natural Products Research Institute)
Baiseitova, Aizhamal (Gyeongsang National University. Institute of Agriculture & Life Science)
Zahoor, Muhammad (University of Malakand. Department of Biochemistry)
Ahmad, Ishaq (Gyeongsang National University. Department of Marine Environmental Engineering)
Ikram, Muhammad (Khyber Medical University. Institute of Pharmaceutical Sciences)
Bakhsh, Allah (National University of Sciences and Technology. Atta-ur-Rahman School of Applied Biosciences)
Shah, Murad Ali (Korea Institute of Science and Technology. Brain Science Institute)
Ali, Imdad (Centre de Recerca en Agrigenòmica)
Idress, Muhammad (Gyeongsang National University. Institute of Agriculture & Life Science)
Ullah, Riaz (King Saud University. Department of Pharmacognosy)
Nasr, Fahd A. (Imam Mohammad Ibn Saud Islamic University. Biology Department)
Al-Zharani, Mohammed (Imam Mohammad Ibn Saud Islamic University. Biology Department)
| Data: |
2024 |
| Resum: |
A rising corpus of research has shown the beneficial effects of probiotic Lactobacilli on human health, contributing to the growing popularity of these microorganisms in recent decades. The gastrointestinal and urinary tracts are home to these bacteria, which play a vital role in the microbial flora of both humans and animals. The Lactobacillus probiotic, i. e, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus reuteri, and Lactobacillus bulgaricus, are highly recognized for their remarkable probiotic qualities. The current study aims to highlight the beneficial effects of probiotics in different health conditions, point out the research gap, and highlight the future directives for the safe use of these probiotics in several health issues. Most importantly, we have added the most recent literature related to the characteristics and usage of these probiotics in clinical and pre-clinical settings. Based on the above statement, we believe that this is the first report on the application of probiotics in human diseases. By providing a deeper knowledge of the complex functions these probiotics play in both human and animal health, our analysis will direct future studies and developments in this rapidly developing field. |
| Drets: |
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.  |
| Llengua: |
Anglès |
| Document: |
Article de revisió ; recerca ; Versió publicada |
| Matèria: |
Lactobacillus ;
Probiotic ;
Gastrointestinal tract ;
Human health |
| Publicat a: |
Gut Microbes, Vol. 16, Issue 1 (November 2024) , art. 2431643, ISSN 1949-0984 |
DOI: 10.1080/19490976.2024.2431643
PMID: 39582101
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Registre creat el 2025-09-23, darrera modificació el 2026-01-02