Non-communicable diseases among women survivors of intimate partner violence : Critical review from a chronic stress framework
Goldberg, Ximena (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Espelt, Carme (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Porta-Casteràs, Daniel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Palao, Diego (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències)
Armario Garcia, Antonio (Universitat Autònoma de Barcelona. Institut de Neurociències)
Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia

Date:	2021
Abstract:	A neurobiological framework of chronic stress proposes that the stress-response system can be functionally altered by the repeated presentation of highly stressful situations over time. These functional alterations mainly affect brain processing and include the dysregulation of the hypothalamic-pituitary-adrenal axis and associated processes. In the present critical review, we translate these results to inform the clinical presentation of women survivors of intimate partner violence (IPV). We approach IPV as a scenario of chronic stress where women are repetitively exposed to threat and coping behaviours that progressively shape their neurobiological response to stress. The changes at the central and peripheral levels in turn correlate with the phenotypes of non-communicable diseases. The reviewed studies clarify the extent of the impact of IPV on women's health in large (N > 10,000) population-based designs, and provide observations on experimental neuroendocrine, immune, neurocognitive and neuroimaging research linking alterations of the stress-response system and disease. This evidence supports the prevention of violence against women as a fundamental action to reduce the prevalence of non-communicable diseases.
Grants:	"la Caixa" Foundation 2017ACUP00277 Agencia Estatal de Investigación SAF2017-83430-R Generalitat de Catalunya 2017/SGR-00457
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Language:	Anglès
Document:	Article de revisió ; Versió acceptada per publicar
Subject:	Intimate partner violence ; Non-communicable disease ; Review ; Stress-response
Published in:	Neuroscience & biobehavioral reviews, Vol. 128 (September 2021) , p. 720-734, ISSN 1873-7528

DOI: 10.1016/j.neubiorev.2021.06.045

Postprint 75 p, 1.9 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Neurociències (INc)
Articles > Published articles