Sex-specific predictors of self-stigma reduction in psychosis resulting from metacognitive interventions : results from a randomised clinical trial
Lamarca, Maria (Parc Sanitari Sant Joan de Déu)
Navarro, José-Blas (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut)
León-Morales, Daniela (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
González Higueras, Fermín (Hospital Universitario de Jaén)
Torres Hernández, Pedro (Hospital Universitario de Jaén)
Cid Colom, Jordi (Institut d'Investigació Biomèdica de Girona)
Birulés, Irene (Parc Sanitari Sant Joan de Déu)
Naides Averard, Naomi (Parc Sanitari Sant Joan de Déu)
Vidal, Carme (Fundació Els Tres Turons)
Garrido García, Gemma (Consorci Sanitari de Terrassa)
Crosas, Josep Maria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Aznar, Ana (Associació Centre Higiene Mental Les Corts (Barcelona, Catalunya))
Palma, Carol (Universitat Ramon Llull. Blanquerna)
Sastre-Buades, Aina (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears))
Sevilla-Llewellyn-Jones, Julia (Hospital Clínico San Carlos (Madrid))
Vallina Fernández, Oscar (Hospital General Sierrallana - Tres Mares)
Gutiérrez, Enrique (Universidad Politécnica de Madrid. Departamento de Matemática Aplicada a las Tecnologías de la Información y las Comunicaciones)
Calvo, Ana (Universidad Complutense de Madrid. Departamento de Personalidad, Evaluación y Psicología Clínica)
ReCoMet Group (Universitat Autònoma de Barcelona)
Ochoa, Susana (Parc Sanitari Sant Joan de Déu)
Barajas Vélez, Ana (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut

Imprint:	SAGE, 2026
Description:	14 pàg.
Abstract:	Background:Research on gender differences in self-stigma among individuals with psychosis is limited. Gender differences have been found in factors associated with self-stigma, such as self-esteem, quality of life, and cognitive insight. Objectives:This study aimed to determine predictors of self-stigma reduction in men and women after receiving Metacognitive Training (MCT) or a combined intervention delivering MCT alongside cognitive rehabilitation. Design:Randomized clinical trial with two intervention branches. Methods:Participants were randomly allocated to one of two conditions: MCT or MCT alongside cognitive rehabilitation. Assessments were carried out before and after the intervention by blinded professionals. Linear mixed models, correlation analyses, and regressions were employed to examine the effect of treatment, relationships between variables, and potential predictors of treatment response in both groups for men and women, respectively. Results:Self-stigma was reduced in both intervention groups, with no significant differences between them, suggesting both interventions were effective. Descriptive analyses revealed women reported higher self-stigma (n = 37, M = 63. 78, SD = 14. 01) than men (n = 40, M = 59. 40, SD = 14. 52). Regression analyses suggest that post-treatment self-stigma was predicted by different predictors according to sex. In women, self-esteem (R2 = 0. 25, β = −2. 31, p = 0. 023) was a significant predictor of post-treatment self-stigma, while in men, quality of life significantly predicted self-stigma scores post-treatment (R2 = 0. 37, β = −0. 62, p < 0. 001). Cognitive insight was not a significant predictor for either sex. Conclusion:Distinct pathways of self-stigma recovery emerged for women and men, underscoring the need for gender-sensitive interventions. These findings underscore the need for tailored stigma-reduction interventions that consider gender-specific factors influencing mental health outcomes. Longitudinal research should assess durability and further clarify gender-related mechanisms.
Grants:	Agencia Estatal de Investigación PID2020-118907RA-I00 Generalitat de Catalunya 2021/SGR-000534 Agencia Estatal de Investigación RED2024-154206-T
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Self-stigma ; Psychosis ; Metacognitive training (MCT) ; Cognitive rehabilitation ; Sex differences ; Internalized stigma ; Psychotic disorders
Published in:	Women's Health, Vol. 22 (2026) , p. 1-14, ISSN 1745-5065

DOI: 10.1177/17455057261440689
PMID: 42531158

14 p, 349.1 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Articles > Research articles
Articles > Published articles