Home > Articles > Search Results: Models animals

Articles

  Search Tips
Advanced Search
Search collections:
Sort by: Display results: Output format:
Articles 24 records found  previous11 - 20next  jump to record: Search took 0.00 seconds. 
11.
11 p, 4.2 MB Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis / Penas Pérez, Clara (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Maloof, M. E. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Stathias, V. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Long, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Tan, S. K. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences) ; Mier, J. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Fang, Y. (The Rockefeller University. Laboratory of Development Neurobiology) ; Valdes, C. (Florida International University. Computing and Information Sciences) ; Rodriguez-Blanco, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Chiang, C. M. (University of Texas Southwestern Medical Center. Simmons Comprehensive Cancer Center. Department of Biochemistry and Department of Pharmacology) ; Robbins, D. J. (University of Miami Miller School of Medicine. Department of Surgery) ; Liebl, D. J. (University of Miami Miller School of Medicine. Department of Surgery) ; Lee, J. K. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Hatten, M. E. (The Rockefeller University. Laboratory of Development Neurobiology) ; Clarke, J. (University of Nebraska. Department of Statistics) ; Ayad, N. G. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences. Center for Therapeutic Innovation. Sylvester Comprehensive Cancer Center. Miami Project to Cure Paralysis)
Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric brain tumor, medulloblastoma. [...]
2019 - 10.1038/s41467-019-10799-5
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 3028  
Detailed record - Creative Commons
12.
25 p, 6.5 MB Impact of chronic risperidone use on behavior and survival of 3xTg-AD mice model of Alzheimer's disease and mice with normal aging / Torres-Lista, V. (Universitat Autònoma de Barcelona. Institut de Neurociències.) ; López-Pousa, S. (Institut d'Assistència Sanitaria. Research Unit and UVaMiD (Memory and Dementia Assessment Unit).) ; Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències.)
Psychosis and/or aggression are common problems in dementia, and when severe or persistent, cause considerable patient distress and disability, caregiver stress, and early institutionalization. In 2005, the Food and Drug Administration (FDA) determined that atypical antipsychotics were associated with a significantly greater mortality risk compared to placebo, which prompted the addition of an FDA black-box warning. [...]
2019 - 10.3389/fphar.2019.01061
Frontiers in Pharmacology, Vol. 10 Núm. SEP (2019) , p. 1061  
Detailed record - Creative Commons
13.
15 p, 4.1 MB Prenatal Betamethasone interferes with immune system development and alters target cells in autoimmune diabetes / Perna-Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ; Pujol-Autonell, Irma (Institut Germans Trias i Pujol) ; Gieras, A. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ; Ampudia Carrasco, Rosa María (Institut Germans Trias i Pujol) ; Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Glau, L. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ; Tolosa, E. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ; Vives Pi, Marta (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Non-genetic factors are crucial in the pathogenesis of type 1 diabetes (T1D), a disease caused by autoimmunity against insulin-producing β-cells. Exposure to medications in the prenatal period may influence the immune system maturation, thus altering self-tolerance. [...]
2019 - 10.1038/s41598-018-37878-9
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 1235  
Detailed record - Creative Commons
14.
11 p, 1.9 MB Efficacy of liposomal amphotericin B and anidulafungin using an antifungal lock technique (ALT) for catheter-related Candida albicans and Candida glabrata infections in an experimental model / Basas Satorras, Jana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Palau Gauthier, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gomis, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Almirante Gragera, Benito (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gavaldà, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Objective: The aims of this study were as follows. First, we sought to compare the in vitro susceptibility of liposomal amphotericin B (LAmB) and anidulafungin on Candida albicans and Candida glabrata biofilms growing on silicone discs. [...]
2019 - 10.1371/journal.pone.0212426
PloS one, Vol. 14 Núm. 2 (february 2019) , p. e0212426  
Detailed record - Creative Commons
15.
20 p, 2.9 MB Pharmacokinetic parameters and mechanism of action of an efficient anti-Aβ single chain antibody fragment / Esquerda-Canals, Gisela (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martí-Clúa, Joaquín (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Villegas Hernández, Sandra (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The success of the targeting of amyloid-β (Aβ) oligomers through immunotherapy in Alzheimer's disease (AD) mouse models has not been translated into the clinics. The use of single- chain variable fragments (scFvs) has been proposed to prevent the potential severe effects of full-length mAbs by precluding crystallizable fraction-mediated microglia activation. [...]
2019 - 10.1371/journal.pone.0217793
PloS one, Vol. 14, Issue 5 (May 2019) , art. e0217793  
Detailed record - Creative Commons
16.
20 p, 2.2 MB Fluid supplementation accelerates epithelial repair during chemical colitis / Burgueño, Juan F. (University of Miami-Leonard. Division of Gastroenterology.) ; Lang, Jessica K. (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Santander, Ana M. (University of Miami-Leonard. Division of Gastroenterology) ; Fernández, Irina (University of Miami-Leonard. Division of Gastroenterology) ; Fernandez, Ester (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Zaias, Julia (University of Miami-Leonard. Department of Pathology and Laboratory Medicine) ; Abreu, Maria T. (University of Miami-Leonard. Division of Gastroenterology)
The dextran sulfate sodium (DSS) model of colitis is a common animal model of inflammatory bowel disease that causes pain and distress. In this study, we aimed to determine whether fluid supplementation can be used as a welfare-based intervention to minimize animal suffering. [...]
2019 - 10.1371/journal.pone.0215387
PloS one, Vol. 14, Issue 4 (April 2019) , art. e0215387  
Detailed record - Creative Commons
17.
33 p, 2.7 MB Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies / Eraña, Hasier (ATLAS Molecular Pharma S. L.) ; Charco, Jorge M. (CIC bioGUNE) ; Di Bari, Michele Angelo (CIC bioGUNE) ; Díaz-Domínguez, Carlos M. (Istituto Superiore di Sanità. Department of Veterinary Public Health and Food Safety.) ; López-Moreno, R. (CIC bioGUNE) ; Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; González-Miranda, E. (CIC bioGUNE) ; Pérez-Castro, Miguel A. (CIC bioGUNE) ; García-Martínez, Sandra (ATLAS Molecular Pharma S. L.) ; Bravo Lopez, Susana Belén (Proteomics Lab. IDIS) ; Fernández-Borges, Natalia (CIC bioGUNE) ; Geijo, Maria V. (NEIKER-Instituto Vasco de Investigación y Desarrollo Agrario) ; D'Agostino, C. (Department of Veterinary Public Health and Food Safety. Istituto Superiore di Sanità) ; Garrido, Joseba M (NEIKER-Instituto Vasco de Investigación y Desarrollo Agrario) ; Bian, J. (Colorado State University. Prion Research Center (PRC).) ; König, A. (Heinrich-Heine-Universität Düsseldorf. Physikalische Biologie.) ; Uluca-Yazgi, B. (Heinrich-Heine-Universität Düsseldorf. Physikalische Biologie.) ; Sabate, R. (Universitat de Barcelona. Institut de Nanociència i Nanotecnologia) ; Khaychuk, V. (Colorado State University. Prion Research Center (PRC).) ; Vanni, Ilaria (Istituto Superiore di Sanità. Department of Veterinary Public Health and Food Safety.) ; Telling, G. C. (Colorado State University. Prion Research Center (PRC).) ; Heise, Henrike (Heinrich-Heine-Universität Düsseldorf. Physikalische Biologie.) ; Nonno, Romolo (Istituto Superiore di Sanità. Department of Veterinary Public Health and Food Safety.) ; Requena, Jesús R (Universidade de Santiago de Compostela) ; Castilla, Joaquín (IKERBasque. Basque Foundation for Science)
The resolution of the three-dimensional structure of infectious prions at the atomic level is pivotal to understand the pathobiology of Transmissible Spongiform Encephalopathies (TSE), but has been long hindered due to certain particularities of these proteinaceous pathogens. [...]
2019 - 10.1371/journal.ppat.1008117
PLOS pathogens, Vol. 15 Núm. 10 (2019) , p. e1008117  
Detailed record - Creative Commons
18.
12 p, 1.4 MB Controllability affects endocrine response of adolescent male rats to stress as well as impulsivity and behavioral flexibility during adulthood / Sanchís Ollé, Maria (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Fuentes, Silvia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Úbeda-Contreras Gallego de la Sacristana, Jesús (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; F. Lalanza, Jaume (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ; Ramos-Prats, A. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Armario Garcia, Antonio (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències)
Exposure to stress during adolescence exerts a long-term impact on behavior and might contribute to the development of several neuropsychiatric disorders. In adults, control over stress has been found to protect from the negative consequences of stress, but the influence of controllability at early ages has not been extensively studied. [...]
2019 - 10.1038/s41598-019-40061-3
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 3180  
Detailed record - Creative Commons
19.
19 p, 6.1 MB Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis / Carballo-Carbajal, Iria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Laguna, Ariadna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Romero-Giménez, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cuadros, Thais (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bové, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martinez-Vicente, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Parent, Annabelle (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González Sepúlveda, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Peñuelas, Núria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Torra, Albert (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodríguez-Galván, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ballabio, Andrea (Telethon Institute of Genetics and Medicine (TIGEM)) ; Hasegawa, Takafumi (Department of Neurology. Tohoku University School of Medicin) ; Bortolozzi, Analía (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Gelpi, Ellen (Institute of Neurology. Medical University of Vienna) ; Vila Bover, Miquel (Institució Catalana de Recerca i Estudis Avançats) ; Universitat Autònoma de Barcelona
2019 - 10.1038/s41467-019-08858-y
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 973  
Detailed record - Creative Commons
20.
17 p, 2.6 MB Succination is increased on select proteins in the brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome / Piroli, G. G. (Department of Pharmacology. Physiology and Neuroscience. University of South Carolina) ; Manuel, A. M. (Department of Pharmacology. Physiology and Neuroscience. University of South Carolina) ; Clapper, A. C. (Department of Pharmacology. Physiology and Neuroscience. University of South Carolina) ; Walla, M. D. (Mass Spectrometry Center. Department of Chemistry and Biochemistry. University of South Carolina) ; Baatz, J. E. (Department of Pharmacology. Physiology and Neuroscience. University of South Carolina) ; Palmiter, Richard D (Howard Hughes Medical Institute and Department of Biochemistry. University of Washington) ; Quintana Puebla, Alberto (Seattle Children's Research Institute) ; Frizzell, N. (Department of Pharmacology. Physiology and Neuroscience. University of South Carolina)
Elevated fumarate concentrations as a result of Krebs cycle inhibition lead to increases in protein succination, an irreversible post-Translational modification that occurs when fumarate reacts with cysteine residues to generate S-(2-succino)cysteine (2SC). [...]
2016 - 10.1074/mcp.M115.051516
Molecular and Cellular Proteomics, Vol. 15 Núm. 2 (february 2016) , p. 445-461  
Detailed record -

Articles : 24 records found   previous11 - 20next  jump to record:
Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.
UAB Digital Repository of Documents :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.6
Maintained by ddd.bib@uab.cat  :: Metadata license:
Working with