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10 p, 509.3 KB Association of Early Progression Independent of Relapse Activity With Long-term Disability After a First Demyelinating Event in Multiple Sclerosis / Tur, Carmen (Hospital Universitari Vall d'Hebron) ; Carbonell-Mirabent, Pere (Hospital Universitari Vall d'Hebron) ; Cobo-Calvo, Álvaro (Hospital Universitari Vall d'Hebron) ; Otero-Romero, Susana (Hospital Universitari Vall d'Hebron) ; Arrambide, Georgina (Hospital Universitari Vall d'Hebron) ; Midaglia, Luciana (Hospital Universitari Vall d'Hebron) ; Castilló, Joaquín (Hospital Universitari Vall d'Hebron) ; Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron) ; Rodríguez Acevedo, Breogán (Hospital Universitari Vall d'Hebron) ; Zabalza, Ana (Hospital Universitari Vall d'Hebron) ; Galan, Ingrid (Hospital Universitari Vall d'Hebron) ; Nos, Carlos (Hospital Universitari Vall d'Hebron) ; Salerno, Annalaura (Hospital Universitari Vall d'Hebron) ; Auger, Cristina (Hospital Universitari Vall d'Hebron) ; Pareto, Deborah (Hospital Universitari Vall d'Hebron) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron) ; Río, Jordi (Hospital Universitari Vall d'Hebron) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ; Rovira, Alex (Hospital Universitari Vall d'Hebron) ; Tintoré, Mar (Hospital Universitari Vall d'Hebron) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
This cohort study investigates the long-term outcomes of patients who develop progression independent of relapse activity after a first demyelinating event in multiple sclerosis. What are the long-term outcomes of patients developing progression independent of relapse activity (PIRA) after a first demyelinating event in multiple sclerosis? In this longitudinal cohort study including 1128 patients with a first demyelinating event in multiple sclerosis, presenting with PIRA was associated with significantly shorter times to developing severe disability compared with not presenting with PIRA. [...]
2022 - 10.1001/jamaneurol.2022.4655
JAMA Neurology, Vol. 80 (december 2022) , p. 151-160  
Detailed record - Creative Commons

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