Fessner, Wolf-Dieter - Resultados de la búsqueda - Depósito Digital de Documentos de la UAB

Buscar colecciones:

Ordenar por:	Mostrar resultados:	Formato de visualización:

Resultados globales: 2 registros encontrados en 0.02 segundos.
Artículos, Encontrados 2 registros

Artículos	Encontrados 2 registros

6 p, 2.1 MB

Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes / Roldán, Raquel (Institut de Química Avançada de Catalunya) ; Hernández, Karel (Institut de Química Avançada de Catalunya) ; Joglar, Jesús (Institut de Química Avançada de Catalunya) ; Bujons, Jordi (Institut de Química Avançada de Catalunya) ; Parella Coll, Teodor (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear) ; Sánchez-Moreno, Israel (University Clermont Auvergne, CNRS, SIGMA Clermont) ; Hélaine, Virgil (University Clermont Auvergne, CNRS, SIGMA Clermont) ; Lemaire, Marielle (University Clermont Auvergne, CNRS, SIGMA Clermont) ; Guérard-Hélaine, Christine (University Clermont Auvergne, CNRS, SIGMA Clermont) ; Fessner, Wolf-Dieter (Technische Universität Darmstadt) ; Clapés, Pere (Institut de Química Avançada de Catalunya)
Asymmetric aldol addition of simple aldehydes and ketones to electrophiles is a cornerstone reaction for the synthesis of unusual sugars and chiral building blocks. We investigated -fructose-6-phosphate aldolase from E. [...]
2018 - DOI (Digital Object Identifier)

10.1021/acscatal.8b02486
ACS catalysis, Vol. 8 (08 2018) , p. 8804-8809

Registro completo -

15 p, 3.1 MB

Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes / Roldán, Raquel (Institut de Química Avançada de Catalunya) ; Hernández, Karel (Institut de Química Avançada de Catalunya) ; Joglar, Jesús (Institut de Química Avançada de Catalunya) ; Bujons, Jordi (Institut de Química Avançada de Catalunya) ; Parella Coll, Teodor (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear) ; Fessner, Wolf-Dieter (Technische Universität Darmstadt) ; Clapés, Pere (Institut de Química Avançada de Catalunya)
Nitrogen heterocycles are structural motifs found in many bioactive natural products and of utmost importance in pharmaceutical drug development. In this work, a stereoselective synthesis of functionalized N-heterocycles was accomplished in two steps, comprising the biocatalytic aldol addition of ethanal and simple aliphatic ketones such as propanone, butanone, 3-pentanone, cyclobutanone, and cyclopentanone to N -Cbz-protected aminoaldehydes using engineered variants of -fructose-6-phosphate aldolase from Escherichia coli (FSA) or 2-deoxy--ribose-5-phosphate aldolase from Thermotoga maritima (DERA) as catalysts. [...]
2019 - DOI (Digital Object Identifier)

10.1002/adsc.201801530
Advanced synthesis & catalysis, Vol. 361, Issue 11 (January 2019) , p. 2673-2687

Registro completo -

Vea también: autores con nombres similares
1	Fessner, W.D.

¿Le interesa recibir alertas sobre nuevos resultados de esta búsqueda?
Defina una alerta personal vía correo electrónico o subscríbase al canal RSS.