Home > Search Results: Hurtado-Navarro, Laura
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Articles, 2 records found
Articles 2 records found  
1.
17 p, 4.1 MB NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy / Hurtado-Navarro, Laura (Instituto Murciano de Investigación Biosanitaria) ; Cuenca-Zamora, Ernesto José (Instituto Murciano de Investigación Biosanitaria) ; Zamora, Lurdes (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bellosillo Paricio, Beatriz (Institut Hospital del Mar d'Investigacions Mèdiques) ; Such, Esperanza (Hospital Universitari i Politècnic La Fe (València)) ; Soler-Espejo, Eva (Hospital Universitario Morales-Meseguer, Centro Regional de Hemodonación, Murcia) ; Martínez-Banaclocha, Helios (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ; Hernández-Rivas, Jesús Maria (Universidad de Salamanca) ; Marco-Ayala, Javier (Hospital Universitario Morales-Meseguer. Murcia) ; Martínez-Alarcón, Laura (Instituto Murciano de Investigación Biosanitaria) ; Linares-Latorre, Lola (Fundació Institut Valencià d'Oncologia) ; García-Ávila, Sara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Amat-Martínez, Paula (Hospital Clínic Universitari (València). Health Research Institute) ; González, Teresa (Universidad de Salamanca) ; Arnan, Montserrat (Institut Català D'Oncologia (ICO)-Hospital Duran I Reynals. IDIBELL) ; Pomares-Marín, Helena (Institut Català D'Oncologia (ICO)-Hospital Duran I Reynals. IDIBELL) ; Carreño-Tarragona, Gonzalo (Hospital 12 de Octubre (Madrid)) ; Chen-Liang, Tzu Hua (Hospital General Universitario Morales Meseguer (Múrcia)) ; Herranz, María T. (Hospital Universitario Morales Meseguer) ; García-Palenciano, Carlos (Hospital Clínico Universitario Virgen de La Arrixaca) ; Morales, María Luz (Hospital General Universitario Morales Meseguer (Múrcia)) ; Jerez, Andrés (Hospital General Universitario Morales Meseguer (Múrcia)) ; Lozano, María L. (Hospital General Universitario Morales Meseguer (Múrcia)) ; Teruel-Montoya, Raúl (Universidad Católica San Antonio (UCAM)) ; Pelegrín, Pablo (University of Murcia) ; Ferrer-Marín, Francisca (Universidad Católica San Antonio (UCAM))
Chronic myelomonocytic leukemia (CMML) is frequently associated with mutations in the rat sarcoma gene (RAS), leading to worse prognosis. RAS mutations result in active RAS-GTP proteins, favoring myeloid cell proliferation and survival and inducing the NLRP3 inflammasome together with the apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), which promote caspase-1 activation and interleukin (IL)-1β release. [...]
2023 - 10.1016/j.xcrm.2023.101329
Cell Reports Medicine, Vol. 4 Núm. 12 (december 2023)  
Detailed record - Creative Commons
2.
9 p, 692.2 KB Increased NLRP3 Inflammasome Activation and Pyroptosis in Patients With Multiple Sclerosis With Fingolimod Treatment Failure / Malhotra, Sunny (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hurtado-Navarro, Laura (Hospital Universitari Vall d'Hebron) ; Pappolla, Agustin (Hospital Universitari Vall d'Hebron) ; Villar, Luisa M. (Hospital Universitari Vall d'Hebron) ; Río, Jordi (Hospital Universitari Vall d'Hebron) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron) ; Pelegrín, Pablo (Hospital Universitari Vall d'Hebron) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Inflammasomes are involved in the pathogenesis of different neuroimmune and neurodegenerative diseases, including multiple sclerosis (MS). In a previous study by our group, the nucleotide-binding oligomerization domain, leucine-rich repeat receptor and pyrin-domain-containing 3 (NLRP3) inflammasome was reported to be associated with the response to interferon-beta in MS. [...]
2023 - 10.1212/NXI.0000000000200100
Neurology® neuroimmunology & neuroinflammation, Vol. 10 (march 2023)  
Detailed record - Creative Commons

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