Resultats globals: 3 registres trobats en 0.02 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
6 p, 731.5 KB A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood : Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort / Stamate, Daniel (University of London) ; Kim, Min (Steno Diabetes Center Copenhagen) ; Proitsi, Petroula (King's College London) ; Westwood, Sarah (University of Oxford) ; Baird, Alison (University of Oxford) ; Nevado-Holgado, Alejo (University of Oxford) ; Hye, Abdul (King's College London) ; Bos, Isabelle (Amsterdam UMC) ; Vos, Stephanie J.B. (Maastricht University) ; Vandenberghe, Rik (Amsterdam UMC) ; Teunissen, Charlotte E. (Amsterdam UMC. University Medical Center) ; Kate, Mara Ten (Amsterdam UMC. University Medical Center) ; Scheltens, Philip (Vrije Universiteit Amsterdam) ; Gabel, Silvy (Laboratory for Cognitive Neurology) ; Meersmans, Karen (Laboratory for Cognitive Neurology) ; Blin, Olivier (Aix-Marseille Université) ; Richardson, Jill (GlaxoSmithKline R&D) ; De Roeck, Ellen (University of Antwerp) ; Engelborghs, Sebastiaan (Vrije Universiteit Brussel (VUB)) ; Sleegers, Kristel (Center for Molecular Neurology. VIB) ; Bordet, Régis (University of Lille) ; Ramit, Lorena (Hospital Clínic i Provincial de Barcelona) ; Kettunen, Petronella (Sahlgrenska Academy at University of Gothenburg) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans (Maastricht University) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Peyratout, Gwendoline (Lausanne University Hospital) ; Tainta, Mikel (Fundacion CITA-alzheimer Fundazioa) ; Johannsen, Peter (Copenhagen University Hospital) ; Freund-Levi, Yvonne (Karolinska Institutet (Estocolm, Suècia)) ; Frölich, Lutz (University of Heidelberg) ; Dobricic, Valerija (University of Lübeck) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Molinuevo, José Luis (Universitat Pompeu Fabra) ; Wallin, Anders (Sahlgrenska Academy at the University of Gothenburg) ; Popp, Julius (Geneva University Hospitals) ; Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ; Bertram, Lars (University of Oslo) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ; Streffer, Johannes (University of Antwerp) ; Visser, Pieter J. (Amsterdam UMC) ; Lovestone, Simon (Janssen-Cilag UK Ltd) ; Legido-Quigley, Cristina (King's College London) ; Universitat Autònoma de Barcelona
Machine learning (ML) may harbor the potential to capture the metabolic complexity in Alzheimer Disease (AD). Here we set out to test the performance of metabolites in blood to categorize AD when compared to CSF biomarkers. [...]
2019 - 10.1016/j.trci.2019.11.001
Alzheimer's & dementia, Vol. 5 (2019) , p. 933-938  
2.
11 p, 783.1 KB Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay / Shi, Liu (University of Oxford) ; Westwood, Sarah (University of Oxford) ; Baird, Alison L. (University of Oxford) ; Winchester, Laura (University of Oxford) ; Dobricic, Valerija (University of Lübeck) ; Kilpert, Fabian (University of Lübeck) ; Hong, Shengjun (University of Lübeck) ; Franke, Andre (Christian-Albrechts-University of Kiel) ; Hye, Abdul (King's College London) ; Ashton, Nicholas J. (South London and Maudsley NHS Foundation) ; Morgan, Angharad R. (Cardiff University) ; Bos, Isabelle (Maastricht University) ; Vos, Stephanie J.B. (Amsterdam UMC. University Medical Center) ; Buckley, Noel J (University of Oxford) ; Kate, Mara ten (Amsterdam UMC. University Medical Center) ; Scheltens, Philip (Amsterdam UMC. University Medical Center) ; Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ; Gabel, Silvy (Laboratory for Cognitive Neurology) ; Meersmans, Karen (Laboratory for Cognitive Neurology) ; Engelborghs, Sebastiaan (VUB University Hospital Brussels (UZ Brussel)) ; De Roeck, Ellen E. (Institute Born-Bunge. University of Antwerp) ; Sleegers, Kristel (Center for Molecular Neurology. VIB) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Blin, Olivier (Aix-Marseille Université) ; Richardson, Jill C. (GlaxoSmithKline R&D) ; Bordet, Régis (University of Lille) ; Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ; Rami, Lorena (Universitat Pompeu Fabra) ; Wallin, Anders (Sahlgrenska Academy at University of Gothenburg) ; Kettunen, Petronella (University of Oxford) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans (Maastricht University) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Popp, Julius (Geneva University Hospitals) ; Peyratout, Gwendoline (Lausanne University Hospital) ; Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ; Tainta, Mikel (CITA-Alzheimer Foundation) ; Johannsen, Peter Copenhagen University Hospital ; Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ; Freund-Levi, Yvonne (King's College London) ; Frölich, Lutz (University of Heidelberg) ; Legido-Quigley, Cristina (Steno Diabetes Center) ; Barkhof, Frederik (UCL Institutes of Neurology and Healthcare Engineering) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ; Baker, Susan (Janssen R&D) ; Morgan, B.Paul (Cardiff University) ; Streffer, Johannes (Janssen R&D. LLC) ; Visser, Pieter Jelle (Karolinska Institutet (Estocolm, Suècia)) ; Bertram, Lars (University of Oslo) ; Lovestone, Simon (University of Oxford) ; Nevado-Holgado, Alejo (University of Oxford) ; Universitat Autònoma de Barcelona
Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. [...]
2019 - 10.1016/j.jalz.2019.06.4951
Alzheimer's & Dementia, Vol. 15 Núm. 11 (november 2019) , p. 1478-1488  
3.
13 p, 1.8 MB Replication study of plasma proteins relating to Alzheimer's pathology / Shi, Liu (University of Oxford. Department of Psychiatry) ; Winchester, Laura M. (University of Oxford. Department of Psychiatry) ; Westwood, Sarah (University of Oxford. Department of Psychiatry) ; Baird, Alison L (University of Oxford. Department of Psychiatry) ; Anand, Sneha N (University of Oxford. Department of Psychiatry) ; Buckley, Noel J. (University of Oxford. Department of Psychiatry) ; Hye, Abdul (Maurice Wohl Clinical Neuroscience. Institute of Psychiatry. Psychology and Neuroscience. Kings College London) ; Ashton, Nicholas J. (University of Gothenburg) ; Bos, Isabelle (Alzheimer Center. VU University Medical Center) ; Vos, Stephanie J.B. (Maastricht University. School for Mental Health and Neuroscience) ; Kate, Mara Ten (Amsterdam UMC. University Medical Center) ; Scheltens, Philip (Amsterdam UMC. University Medical Center) ; Teunissen, Charlotte E. (Amsterdam University Medical Centers (AUMC)) ; Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ; Gabel, Silvy (KU Leuven. Laboratory for Cognitive Neurology) ; Meersmans, Karen (KU Leuven. Laboratory for Cognitive Neurology) ; Engelborghs, Sebastiaan (Department of Neurology. UZ Brussel and Center for Neurociences (C4N). Vrije Universiteit Brussel) ; De Roeck, Ellen E (Department of Neurology and Memory Clinic. Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken) ; Sleegers, Kristel (University of Antwerp. Institute Born-Bunge) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Blin, Olivier (AIX marseille university. INS. Ap-hm) ; Richardson, Jill C. (Neurosciences Therapeutic Area. GlaxoSmithKline R&D) ; Bordet, Régis (Inserm. University of Lille. CHU Lille) ; Molinuevo, José Luis (Barcelonaβeta Brain Research Center (BBRC)) ; Rami Gonzalez, Lorena (Barcelonaβeta Brain Research Center (BBRC)) ; Wallin, Anders (Institute of Neuroscience and Physiology. Sahlgrenska Academy at University of Gothenburg) ; Kettunen, Petronella (Institute of Neuroscience and Physiology. Sahlgrenska Academy at University of Gothenburg) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans (Maastricht University. School for Mental Health and Neuroscience) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Popp, Julius (Geriatric Psychiatry. Department of Mental Health and Psychiatry. Geneva University Hospitals) ; Peyratout, Gwendoline (Lausanne University Hospital) ; Martinez-Lage, Pablo (CITA-Alzheimer Foundation) ; Tainta, Mikel (CITA-Alzheimer Foundation) ; Johannsen, Peter (Danish Dementia Research Centre. Rigshospitalet. Copenhagen University Hospital) ; Freund-Levi, Yvonne (Karolinska Institutet Center for Alzheimer Research. Division of Clinical Geriatrics. School of Medical Sciences Örebro University and Department of Neurobiology. Caring Sciences and Society (NVS)) ; Frölich, Lutz (Department of Geriatric Psychiatry. Zentralinstitut für Seelische Gesundheit. University of Heidelberg) ; Dobricic, Valerija (Lübeck Interdisciplinary Platform for Genome Analytics. Institutes of Neurogenetics and Cardiogenetics. University of Lübeck) ; Legido-Quigley, Cristina (The Systems Medicine Group. Steno Diabetes Center) ; Barkhof, Frederik (UCL Institutes of Neurology and Healthcare Engineering) ; Andreasson, Ulf (Clinical Sahlgrenska University Hospital) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ; Streffer, Johannes (UCB. Braine-l'Alleud. Belgium. formerly Janssen R&D. LLC Beerse) ; Lill, Christina M. (Ageing Epidemiology Research Unit. School of Public Health. Imperial College) ; Bertram, Lars (Department of Psychology. University of Oslo) ; Visser, Pieter Jelle (Alzheimer Center. VU University Medical Center) ; Kolb, Hartmuth C. (Janssen R&D) ; Narayan, Vaibhav A. (Janssen R&D) ; Lovestone, Simon (Janssen R&D) ; Nevado-Holgado, Alejo (Department of Psychiatry. University of Oxford)
Introduction: This study sought to discover and replicate plasma proteomic biomarkers relating to Alzheimer's disease (AD) including both the "ATN" (amyloid/tau/neurodegeneration) diagnostic framework and clinical diagnosis. [...]
2021 - 10.1002/alz.12322
Alzheimer's & Dementia, Vol. 17 Núm. 9 (september 2021) , p. 1452-1464  

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