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1.
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12 p, 3.1 MB |
Metabolic network alterations as a supportive biomarker in dementia with Lewy bodies with preserved dopamine transmission
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Stockbauer, Anna (German Center for Neurodegenerative Diseases) ;
Beyer, Leonie (University Hospital, LMU Munich) ;
Huber, Maria (University Hospital, LMU Munich) ;
Kreuzer, Annika (University Hospital, LMU Munich) ;
Palleis, Carla (Munich Cluster for Systems Neurology) ;
Katzdobler, Sabrina (Munich Cluster for Systems Neurology) ;
Rauchmann, Boris-Stephan (University Hospital, LMU Munich) ;
Morbelli, Silvia (University of Genoa) ;
Chincarini, Andrea (National Institute of Nuclear Physics) ;
Bruffaerts, Rose (University of Antwerp) ;
Vandenberghe, Rik (University Hospitals Leuven) ;
Kramberger, Milica G. (University Medical Centre) ;
Trost, Maja (University of Ljubljana) ;
Garibotto, Valentina (Geneva University) ;
Nicastro, Nicolas (Geneva University Hospitals) ;
Lathuilière, Aurélien (Geneva University Hospitals) ;
Lemstra, Afina W. (Vrije Universiteit Amsterdam) ;
van Berckel, Bart N. M. (Vrije Universiteit Amsterdam) ;
Pilotto, Andrea (University of Brescia) ;
Padovani, Alessandro (University of Brescia) ;
Ochoa-Figueroa, Miguel A. (Linköping University) ;
Davidsson, Anette (Linköping University) ;
Camacho, Valle (Institut d'Investigació Biomèdica Sant Pau) ;
Peira, Enrico (University of Genoa) ;
Bauckneht, Matteo (IRCCS Ospedale Policlinico San Martino) ;
Pardini, Matteo (IRCCS Ospedale Policlinico San Martino) ;
Sambuceti, Gianmario (University of Genoa) ;
Aarsland, Dag (King's College) ;
Nobili, Flavio (IRCCS Ospedale Policlinico San Martino) ;
Gross, Mattes (University Hospital, LMU Munich) ;
Vöglein, Jonathan (German Center for Neurodegenerative Diseases) ;
Perneczky, Robert (Imperial College) ;
Pogarell, Oliver (University Hospital, LMU Munich) ;
Buerger, Katharina (University of Munich) ;
Franzmeier, Nicolai (German Center for Neurodegenerative Diseases) ;
Danek, Adrian (German Center for Neurodegenerative Diseases) ;
Levin, Johannes (Munich Cluster for Systems Neurology) ;
Höglinger, Günter U. (Munich Cluster for Systems Neurology) ;
Bartenstein, Peter (Munich Cluster for Systems Neurology) ;
Cumming, Paul (Queensland University of Technology) ;
Rominger, Axel (University of Bern) ;
Brendel, Matthias (Munich Cluster for Systems Neurology) ;
Universitat Autònoma de Barcelona
Metabolic network analysis of FDG-PET utilizes an index of inter-regional correlation of resting state glucose metabolism and has been proven to provide complementary information regarding the disease process in parkinsonian syndromes. [...]
2023 -  10.1007/s00259-023-06493-w
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 51 (november 2023) , p. 1023-1034
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2.
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11 p, 2.6 MB |
Metabolic Correlates of Dopaminergic Loss in Dementia with Lewy Bodies
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Huber, Maria (LMU Munich) ;
Beyer, Leonie (LMU Munich) ;
Prix, Catharina (LMU Munich) ;
Schönecker, Sonja (LMU Munich) ;
Palleis, Carla (LMU Munich) ;
Rauchmann, Boris-Stephan (LMU Munich) ;
Morbelli, Silvia (University of Genoa) ;
Chincarini, Andrea (Genoa section) ;
Bruffaerts, Rose (University Hospitals Leuven (Bèlgica)) ;
Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ;
Van Laere, Koen (University Hospitals Leuven (Bèlgica)) ;
Kramberger, Milica G. (University Medical Centre) ;
Trost, Maja (University Medical Centre) ;
Grmek, Marko (University Medical Centre) ;
Garibotto, Valentina (Geneva University) ;
Nicastro, Nicolas (University of Cambridge) ;
Frisoni, Giovanni B. (Geneva University Hospitals) ;
Lemstra, Afina W. (VU Medical Center Alzheimer Center) ;
van der Zande, Jessica (VU Medical Center Alzheimer Center) ;
Pilotto, Andrea (Isidoro Hospital) ;
Padovani, Alessandro (University of Brescia) ;
Garcia-Ptacek, Sara (Internal Medicine) ;
Savitcheva, Irina (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Ochoa-Figueroa, Miguel A. (Linköping University) ;
Davidsson, Anette (Linköping University Hospital) ;
Camacho, Valle (Institut d'Investigació Biomèdica Sant Pau) ;
Peira, Enrico (University of Genoa) ;
Arnaldi, Dario (University of Genoa) ;
Bauckneht, Matteo (University of Genoa) ;
Pardini, Matteo (Clinical Neurology. Department of Neuroscience (DINOGMI). University of Genoa) ;
Sambuceti, Gianmario (University of Genoa) ;
Vöglein, Jonathan (DZNE-German Center for Neurodegenerative Diseases) ;
Schnabel, Jonas (LMU Munich) ;
Unterrainer, Marcus (LMU Munich) ;
Perneczky, Robert (University of Munich) ;
Pogarell, Oliver (LMU Munich) ;
Buerger, Katharina (University of Munich) ;
Catak, Cihan (University of Munich) ;
Bartenstein, Peter (Munich Cluster for Systems Neurology (SyNergy)) ;
Cumming, Paul (Queensland University of Technology) ;
Ewers, Michael (DZNE-German Center for Neurodegenerative Diseases) ;
Danek, Adrian (Ludwig-Maximilians-Universität) ;
Levin, Johannes (Munich Cluster for Systems Neurology (SyNergy)) ;
Aarsland, Dag (King's College London) ;
Nobili, Flavio (University of Genoa) ;
Rominger, Axel (University of Bern) ;
Brendel, Matthias (Munich Cluster for Systems Neurology (SyNergy)) ;
Universitat Autònoma de Barcelona
Striatal dopamine deficiency and metabolic changes are well-known phenomena in dementia with Lewy bodies and can be quantified in vivo by I-Ioflupane brain single-photon emission computed tomography of dopamine transporter and F-fluorodesoxyglucose PET. [...]
2020 - 10.1002/mds.27945
Movement Disorders, Vol. 35 Núm. 4 (january 2020) , p. 595-605
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3.
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15 p, 294.1 KB |
The reliability of a deep learning model in clinical out-of-distribution MRI data : A multicohort study
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Mårtensson, Gustav (Karolinska Institutet (Estocolm, Suècia)) ;
Ferreira, Daniel (Karolinska Institutet (Estocolm, Suècia)) ;
Granberg, Tobias (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Cavallin, Lena (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Oppedal, Ketil (University of Stavanger) ;
Padovani, Alessandra (University of Brescia) ;
Rektorova, Irena (Masaryk University) ;
Bonanni, Laura (University G d'Annunzio of Chieti-Pescara) ;
Pardini, Matteo (University of Genoa and Neurology Clinics) ;
Kramberger, Milica G. (Univerza V Ljubljani) ;
Taylor, John-Paul (Newcastle University) ;
Hort, Jakub (Charles University) ;
Snædal, Jón (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Blanc, Frederic (University of Strasbourg and French National Centre for Scientific Research (CNRS)) ;
Antonini, Angelo (University of Padua) ;
Mecocci, Patrizia (University of Perugia) ;
Vellas, Bruno (University of Toulouse) ;
Tsolaki, Magda (3rd Aristotle University of Thessaloniki) ;
Kłoszewska, Iwona (Medical University of Lodz) ;
Soininen, H. (Kuopio University Hospital ( Finlàndia)) ;
Lovestone, S. (University of Oxford) ;
Simmons, A. (King's College London) ;
Aarsland, Dag (King's College London) ;
Westman, Eric (King's College London) ;
Universitat Autònoma de Barcelona
Deep learning (DL) methods have in recent years yielded impressive results in medical imaging, with the potential to function as clinical aid to radiologists. However, DL models in medical imaging are often trained on public research cohorts with images acquired with a single scanner or with strict protocol harmonization, which is not representative of a clinical setting. [...]
2020 - 10.1016/j.media.2020.101714
Medical Image Analysis, Vol. 66 (december 2020) , p. 101714
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4.
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9 p, 227.9 KB |
Complementary pre-screening strategies to uncover hidden prodromal and mild Alzheimer's disease : Results from the MOPEAD project
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Boada, Mercè (Universitat Internacional de Catalunya) ;
Rodrigo, Adrián (GMV SECURE E SOLUTIONS) ;
Jessen, Frank (Faculty of Medicine and University Hospital Cologne) ;
Wimblad, Bengt (Karolinska Univ Hospital) ;
Kramberger, Milica G. (Univerza V Ljubljani) ;
Visser, Pieter Jelle (Maastricht University) ;
Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron) ;
Rodríguez-Gomez, Octavio (Universitat Internacional de Catalunya) ;
Ciudin, Andreea (Hospital Universitari Vall d'Hebron) ;
Georges, Jean (Alzheimer Europe) ;
Dumas, Annete (ASDM Consulting) ;
Maguire, Peggy (European Institute of Women's Health) ;
Krivec, David (Zdruzenje Spomincica) ;
Wimo, Anders (Karolinska Institutet (Estocolm, Suècia)) ;
Valero, Sergi (Instituto de Salud Carlos III) ;
Alegret, Montserrat (Instituto de Salud Carlos III) ;
Jamilis, Laura (GMV SECURE E SOLUTIONS) ;
Zwan, Marissa (Vrije Universiteit Amsterdam) ;
Sannemann, Lena (Faculty of Medicine and University Hospital Cologne) ;
Arrufat, Jordi (EAP Sarrià-Vallvidrera-Les Planes) ;
Stomrud, Erik (Region Kalmar County) ;
Johansson, Gunilla (Karolinska Institutet (Estocolm, Suècia)) ;
Glaysher, Bridget (Modus Research and Innovation Limited) ;
Stewart, Neil (Modus Research and Innovation Limited) ;
Belger, Mark (Eli Lilly and Company (Lilly UK)) ;
Iradier, Fatima (Eli Lilly and Company) ;
Campo, Laura (Eli Lilly and Company) ;
Universitat Autònoma de Barcelona
The Models of Patient Engagement for Alzheimer's Disease (MOPEAD) project was conceived to explore innovative complementary strategies to uncover hidden prodromal and mild Alzheimer's disease (AD) dementia cases and to raise awareness both in the general public and among health professionals about the importance of early diagnosis. [...]
2021 - 10.1002/alz.12441
Alzheimer's & Dementia, Vol. 18 (july 2021) , p. 1119-1127
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5.
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15 p, 2.9 MB |
Adopting transfer learning for neuroimaging : a comparative analysis with a custom 3D convolution neural network model
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Soliman, Amira (Halmstad University) ;
Chang, Jose R. (National Cheng Kung University in Tainan) ;
Etminani, Kobra (Halmstad University) ;
Byttner, Stefan (Halmstad University) ;
Davidsson, Anette (Institution of Medicine and Health Sciences) ;
Martínez-Sanchis, Begoña (Hospital Universitari i Politècnic La Fe (València)) ;
Camacho, Valle (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Bauckneht, Matteo (IRCCS Ospedale Policlinico San Martino) ;
Stegeran, Roxana (Linköping University Hospital) ;
Ressner, Marcus (Linköping University Hospital) ;
Agudelo-Cifuentes, Marc (Hospital Universitari i Politècnic La Fe (València)) ;
Chincarini, Andrea (National Institute of Nuclear Physics) ;
Brendel, Matthias (University Hospital) ;
Rominger, Axel (University Hospital Bern) ;
Bruffaerts, Rose (University of Antwerp) ;
Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ;
Kramberger, Milica G. (University Medical Centre) ;
Trost, Maja (Univerza V Ljubljani) ;
Nicastro, Nicolas (Geneva University Hospitals (Suïssa)) ;
Frisoni, Giovanni B. (University Hospitals) ;
Lemstra, Afina W. (VU Medical Center Alzheimer Center) ;
Berckel, Bart N. M. van (Vrije Universiteit Amsterdam) ;
Pilotto, Andrea (University of Brescia) ;
Padovani, Alessandro (IRCCS Ospedale Policlinico San Martino) ;
Morbelli, Silvia (Stavanger University Hospital) ;
Aarsland, Dag (King's College London) ;
Nobili, Flavio (University of Genoa) ;
Garibotto, Valentina (Geneva University) ;
Ochoa-Figueroa, Miguel (Linköping University) ;
Universitat Autònoma de Barcelona
In recent years, neuroimaging with deep learning (DL) algorithms have made remarkable advances in the diagnosis of neurodegenerative disorders. However, applying DL in different medical domains is usually challenged by lack of labeled data. [...]
2022 - 10.1186/s12911-022-02054-7
BMC Medical Informatics and Decision Making, Vol. 22 (december 2022)
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6.
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22 p, 3.7 MB |
A 3D deep learning model to predict the diagnosis of dementia with Lewy bodies, Alzheimer's disease, and mild cognitive impairment using brain 18F-FDG PET
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Etminani, Kobra (Center for Applied Intelligent Systems Research (CAISR). Halmstad University) ;
Soliman, Amira (Center for Applied Intelligent Systems Research (CAISR). Halmstad University) ;
Davidsson, Anette (Department of Clinical Physiology. Department of Health. Medicine and Caring Sciences. Linköping University) ;
Chang, Jose R. (National Cheng Kung University in Tainan) ;
Martínez-Sanchis, Begoña (Hospital Universitari i Politècnic La Fe (València)) ;
Byttner, Stefan (Center for Applied Intelligent Systems Research (CAISR). Halmstad University) ;
Camacho, Valle (Institut d'Investigació Biomèdica Sant Pau) ;
Bauckneht, Matteo (Nuclear Medicine Unit. IRCCS Ospedale Policlinico San Martino) ;
Stegeran, Roxana (Department of Diagnostic Radiology. Linköping University Hospital) ;
Ressner, Marcus (Department of Medical Physics. Linköping University Hospital) ;
Agudelo-Cifuentes, Marc (Hospital Universitari i Politècnic La Fe (València)) ;
Chincarini, Andrea (National Institute of Nuclear Physics (INFN)) ;
Brendel, Matthias (Department of Nuclear Medicine. University Hospital. LMU Munich) ;
Rominger, Axel (Department of Nuclear Medicine. Inselspital. University Hospital Bern) ;
Bruffaerts, Rose (Biomedical Research Institute. Hasselt University) ;
Vandenberghe, Rik (Neurology Department. University Hospitals Leuven) ;
Kramberger, Milica G. (Department of Neurology. University Medical Centre) ;
Trost, Maja (Univerza V Ljubljani) ;
Nicastro, Nicolas (Department of Clinical Neurosciences. Geneva University Hospitals) ;
Frisoni, Giovanni B. (LANVIE (Laboratoire de Neuroimagerie du Vieillissement). Department of Psychiatry. University Hospitals) ;
Lemstra, Afina W. (Department of Neurology. Alzheimer Center) ;
van Berckel, Bart N.M. (Department of Radiology & Nuclear Medicine. Amsterdam UMC. location VUmc) ;
Pilotto, Andrea (Parkinson's Disease Rehabilitation Centre) ;
Padovani, Alessandro (Neurology Unit. Department of Clinical and Experimental Sciences. University of Brescia) ;
Morbelli, Silvia (Department of Health Sciences. University of Genoa) ;
Aarsland, Dag (Department of Old Age Psychiatry. Institute of Psychiatry. Psychology and Neuroscience. King's College London) ;
Nobili, Flavio (Clinical Neurology. IRCCS Ospedale Policlinico San Martino) ;
Garibotto, Valentina (Division of Nuclear Medicine and Molecular Imaging. University Hospitals of Geneva and NIMTLab. Faculty of Medicine. University of Geneva) ;
Ochoa-Figueroa, Miguel (Center for Medical Image Science and Visualization (CMIV). Linköping University) ;
Universitat Autònoma de Barcelona
Purpose: The purpose of this study is to develop and validate a 3D deep learning model that predicts the final clinical diagnosis of Alzheimer's disease (AD), dementia with Lewy bodies (DLB), mild cognitive impairment due to Alzheimer's disease (MCI-AD), and cognitively normal (CN) using fluorine 18 fluorodeoxyglucose PET (18F-FDG PET) and compare model's performance to that of multiple expert nuclear medicine physicians' readers. [...]
2022 - 10.1007/s00259-021-05483-0
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 49 Núm. 2 (january 2022) , p. 563-584
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7 p, 823.4 KB |
Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease
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Jost, Stefanie Theresa (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Visser-Vandewalle, Veerle (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Stereotaxy and Functional Neurosurgery) ;
Rizos, Alexandra Marianne (King's College London. Parkinson Foundation International Centre of Excellence) ;
Loehrer, Philipp Alexander (Department of Neurology. University Hospital Giessen and Marburg. Campus Marburg) ;
Silverdale, Monty (Department of Neurology and Neurosurgery. Salford Royal NHS Foundation Trust. Manchester Academic Health Science Centre. University of Manchester) ;
Evans, Julian (Department of Neurology and Neurosurgery. Salford Royal NHS Foundation Trust. Manchester Academic Health Science Centre. University of Manchester) ;
Samuel, Michael (King's College London. Parkinson Foundation International Centre of Excellence) ;
Petry-Schmelzer, Jan Niklas (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Sauerbier, Anna (Institute of Psychiatry. Psychology and Neuroscience. King's College London) ;
Gronostay, Alexandra (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Barbe, Michael T. (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Fink, Gereon R. (Cognitive Neuroscience. Institute of Neuroscience and Medicine (INM-3). Research Centre Jülich) ;
Ashkan, Keyoumars (King's College London. Parkinson Foundation International Centre of Excellence) ;
Antonini, Angelo (Padova University. Department of Neurosciences (DNS)) ;
Martinez-Martin, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Chaudhuri, Kallol Ray (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Timmermann, Lars (University Hospital Giessen and Marburg) ;
Dafsari, Haidar S. (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Bhidayasiri, Roongroj (Chulalongkorn Centre of Excellence for Parkinson's Disease & Related Disorders. Department of Medicine. Faculty of Medicine. Chulalongkorn University and King Chulalongkorn Memorial Hospital. Thai Red Cross Society) ;
Falup-Pecurariu, Cristian (Faculty of Medicine. Transilvania University of Brașov) ;
Jeon, Beomseok (Department of Neurology. Seoul National University College of Medicine) ;
Leta, Valentina (King's College London. Institute of Psychiatry. Psychology & Neuroscience) ;
Borghammer, Per (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Odin, Per (University of Lund. Faculty of Medicine) ;
Schrag, Anette (UCL Institute of Neurology (Regne Unit)) ;
Storch, Alexander (German Center for Neurodegenerative Diseases (DZNE). Research Site Dresden) ;
Rodríguez-Violante, Mayela (Movement Disorders Clinic. National Institute of Neurology and Neurosurgery) ;
Weintraub, Daniel (Parkinson's Disease and Mental Illness Research. Education and Clinical Centers. Philadelphia Veterans Affairs Medical Center) ;
Adler, Charles (The Parkinson's Disease and Movement Disorders Center. Department of Neurology. Mayo Clinic) ;
Barone, Paolo (Center for Neurodegenerative Diseases (CEMAND). Neuroscience Section. University of Salerno) ;
Brooks, David J. (Department of Nuclear Medicine and PET Centre. Aarhus University Hospital) ;
Brown, Richard (Department of Medicine. University of Birmingham Institute of Cardiovascular Sciences. City Hospital) ;
Cantillon, Marc (Reviva Pharmaceuticals. Inc) ;
Carroll, Camille (Faculty of Medicine and Dentistry. University of Plymouth) ;
Coelho, Miguel (FAS Center for Systems Biology. Harvard University) ;
Henriksen, Tove (Movement Disorder Clinic. University Hospital of Bispebjerg) ;
Hu, Michele (Nuffield Department of Clinical Neurosciences. University of Oxford) ;
Jenner, Peter (Neurodegenerative Diseases Research Group. Institute of Pharmaceutical Sciences. Faculty of Life Sciences and Medicine. King's College London) ;
Kramberger, Milica (Department of Neurology. University Medical Centre Ljubljana) ;
Kumar, Padma (Parkinson's Disease Service for the Older Person. Rankin Park Centre. John Hunter Hospital. HNELHD) ;
Kurtis, Monica M. (Functional Movement Disorders Unit. Movement Disorders Program. Neurology Department. Hospital Ruber Internacional) ;
Lewis, Simon (Brain and Mind Centre. University of Sydney) ;
Litvan, Irene (Department of Neurosciences Movement Disorders Center. University of California) ;
Lyons, Kelly (University of Kansas Medical Center) ;
Martino, Davide (Department of Clinical Neurosciences. University of Calgary & Hotchkiss Brain Institute) ;
Masellis, Mario (Hurvitz Brain Sciences Program. Sunnybrook Research Institute) ;
Mochizuki, Hideki (Department of Neurology. Osaka University Graduate School of Medicine) ;
Morley, James F. (Department of Neurology. University of Pennsylvania) ;
Nirenberg, Melissa (Department of Neurology. NYU School of Medicine) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Panicker, Jalesh (Neurology. National Hospital for Neurology & Neurosurgery) ;
Pavese, Nicola (Newcastle Magnetic Resonance Centre & Positron Emission Tomography Centre. Newcastle University. Campus for Ageing & Vitality) ;
Pekkonen, Eero (Department of Neurology. Helsinki University Hospital. and Department of Neurological Sciences (Neurology). University of Helsinki) ;
Postuma, Ron (Research Institute of McGill University Health Centre) ;
Rosales, Raimon L. (Center for Neurodiagnostic and Therapeutic Services. Metropolitan Medical Center) ;
Schapira, Anthony (Department of Clinical Neurosciences. University College London (UCL) Institute of Neurology. Royal Free Campus. Rowland Hill Street) ;
Simuni, Tanya (Department of Neurology. Northwestern University. Feinberg School of Medicine) ;
Stocchi, Fabrizio (University and Institute for Research and Medical Care. IRCCS San Raffaele) ;
Subramanian, Indu (UCLA/West LA VA) ;
Tagliati, Michele (Cedars-Sinai Medical Center) ;
Tinazzi, Michele (Department of Neuroscience. Biomedicine. and Movement. University of Verona) ;
Toledo, Jon (Department of Neurology. Houston Methodist Hospital) ;
Tsuboi, Yoshio (Department of Neurology. Fukuoka University) ;
Walker, Richard (Northumbria Healthcare NHS Foundation Trust. North Tyneside General Hospital. Rake Lane)
To identify predictors of 36-month follow-up quality of life (QoL) outcome after bilateral subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD). In this ongoing, prospective, multicenter international study (Cologne, Manchester, London) including 73 patients undergoing STN-DBS, we assessed the following scales preoperatively and at 6-month and 36-month follow-up: PD Questionnaire-8 (PDQ-8), NMSScale (NMSS), Scales for Outcomes in PD (SCOPA)-motor examination, -activities of daily living, and -complications, and levodopa equivalent daily dose (LEDD). [...]
2021 - 10.1038/s41531-021-00174-x
NPJ Parkinson's disease, Vol. 7 Núm. 1 (december 2021) , p. 48
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15 p, 570.6 KB |
C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts
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Costa, Beatrice ;
Manzoni, Claudia ;
Bernal-Quiros, Manuel ;
Kia, Demis A. ;
Aguilar Barberà, Miquel ;
Alvarez, Ignacio ;
Alvarez, Victoria ;
Andreassen, Ole A. ;
Anfossi, Maria ;
Bagnoli, Silvia ;
Benussi, Luisa ;
Bernardi, Livia ;
Binetti, Giuliano ;
Blackburn, Daniel ;
Boada, Mercè ;
Borroni, Barbara ;
Bowns, Lucy ;
Bråthen, Geir ;
Bruni, Amalia ;
Chiang, Huei-Hsin ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Colville, Shuna ;
Conidi, Maria E. ;
Cope, Tom E. ;
Cruchaga, Carlos ;
Cupidi, Chiara ;
Di Battista, Maria Elena ;
Diehl-Schmid, Janine ;
Diez-Fairen, Monica ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Durante, Elisabetta ;
Flisar, Dušan ;
Frangipane, Francesca ;
Galimberti, Daniela ;
Gallo, Maura ;
Gallucci, Maurizio ;
Ghidoni, Roberta ;
Graff, Caroline ;
Grafman, Jordan H. ;
Grossman, Murray ;
Hardy, John ;
Hernández, Isabel ;
Holloway, Guy J. T. ;
Huey, Edward D. ;
Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Karydas, Anna ;
Khoshnood, Behzad ;
Kramberger, Milica G. ;
Kristiansen, Mark ;
Lewis, Patrick ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Madhan, Gaganjit K. ;
Maletta, Raffaele ;
Maver, Aleš ;
Menendez-Gonzalez, Manuel ;
Milan, Graziella ;
Miller, Bruce L. ;
Mol, Merel O. ;
Momeni, Parastoo ;
Moreno-Grau, Sonia ;
Morris, Chris M. ;
Nacmias, Benedetta ;
Nilsson, Christer ;
Novelli, Valeria ;
Öijerstedt, Linn ;
Padovani, Alessandro ;
Pal, Suvankar ;
Panchbhaya, Yasmin ;
Pastor, Pau ;
Peterlin, Borut ;
Piaceri, Irene ;
Pickering-Brown, S. ;
Pijnenburg, Yolande ;
Puca, Annibale A. ;
Rainero, Innocenzo ;
Rendina, Antonella ;
Richardson, Anna M. T. ;
Rogaeva, Ekaterina ;
Rogelj, Boris ;
Rollinson, Sara ;
Rossi, Giacomina ;
Rossmeier, Carola ;
Rowe, James B. ;
Rubino, Elisa ;
Ruiz, Agustín ;
Sanchez-Valle, Raquel ;
Sando, Sigrid B. ;
Santillo, Alexander F. ;
Saxon, Jennifer ;
Scarpini, Elio ;
Serpente, Maria ;
Smirne, Nicoletta ;
Sorbi, Sandro ;
Suh, EunRan ;
Tagliavini, Fabrizio ;
Thompson, Jennifer C. ;
Trojanowski, John Q. ;
Van Deerlin, Vivianna M. ;
Van der Zee, Julie ;
Van Broeckhoven, Christine ;
van Rooij, Jeroen ;
Van Swieten, John C. ;
Veronesi, Arianna ;
Vitale, Emilia ;
Waldö, Maria L. ;
Woodward, Cathy ;
Yokoyama, Jennifer ;
Escott-Price, Valentina ;
Polke, James M. ;
Ferrari, Raffaele ;
Universitat Autònoma de Barcelona
We sought to characterize C9orf72 expansions in relation to genetic ancestry and age at onset (AAO) and to use these measures to discriminate the behavioral from the language variant syndrome in a large pan-European cohort of frontotemporal lobar degeneration (FTLD) cases. [...]
2020 - 10.1212/WNL.0000000000010914
Neurology, Vol. 95 (december 2020) , p. e3288-e3302
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9 p, 763.7 KB |
The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies
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Abdelnour, Carla (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ferreira, Daniel (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ;
Oppedal, Ketil (Department of Electrical Engineering and Computer Science, University of Stavanger, Stavanger, Norway) ;
Cavallin, Lena (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Bousiges, Olivier (Hôpitaux Universitaire de Strasbourg (Estrasburg, França)) ;
Wahlund, Lars-Olof (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ;
Hort, Jakub (Charles University (Praga, República Txeca)) ;
Nedelska, Zuzana (Charles University (Praga, República Txeca)) ;
Padovani, Alessandro (University of Brescia (Itàlia)) ;
Pilotto, Andrea (University of Brescia, Brescia (Itàlia)) ;
Bonanni, Laura (University G d'Annunzio of Chieti-Pescara (Chieti, Itàlia)) ;
Kramberger, Milica G. (University of Ljubljana (Eslovènia)) ;
Boada, Mercè (Institut Català de Neurociènces Aplicades) ;
Westman, Eric (King's College London) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Blanc, Frédéric (Hôpitaux Universitaire de Strasbourg) ;
Aarsland, Dag (King's College London. Institute of Psychiatry, Psychology & Neuroscience)
Alzheimer's disease (AD)-related pathology is frequently found in patients with dementia with Lewy bodies (DLB). However, it is unknown how amyloid-β and tau-related pathologies influence neurodegeneration in DLB. [...]
2020 - 10.1016/j.nicl.2020.102333
NeuroImage, Vol. 27 (july 2020)
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