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16 p, 1.6 MB Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans / Sommerer, Yasmine (University of Lübeck) ; Dobricic, Valerija (University of Lübeck) ; Schilling, Marcel (University of Lübeck) ; Ohlei, Olena (University of Lübeck) ; Bartrés-Faz, David (Campus Clínic August Pi i Sunyer) ; Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ; Demuth, Ilja (Charité - Universitätsmedizin Berlin) ; Düzel, Sandra (Max Planck Institute for Human Development) ; Franzenburg, Sören (Christian-Albrechts-University of Kiel) ; Fuß, Janina (Christian-Albrechts-University of Kiel) ; Lindenberger, Ulman (Max Planck Institute for Human Development) ; Pascual Leone, Álvaro (Harvard Medical School) ; Sabet, Sanaz Sedghpour (Christian-Albrechts-University of Kiel) ; Solé-Padullés, Cristina (Campus Clínic August Pi i Sunyer) ; Tormos, Josep M. (Institut Germans Trias i Pujol. Institut Guttmann) ; Vetter, Valentin Max (Charité - Universitätsmedizin Berlin) ; Wesse, Tanja (Christian-Albrechts-University of Kiel) ; Franke, Andre (Christian-Albrechts-University of Kiel) ; Lill, Christina M. (Imperial College London) ; Bertram, Lars (University of Oslo) ; Universitat Autònoma de Barcelona
The decline in episodic memory (EM) performance is a hallmark of cognitive aging and an early clinical sign in Alzheimer's disease (AD). In this study, we conducted an epigenome-wide association study (EWAS) using DNA methylation (DNAm) profiles from buccal and blood samples for cross-sectional (n = 1019) and longitudinal changes in EM performance (n = 626; average follow-up time 5. [...]
2022 - 10.3390/biomedicines10112798
Biomedicines, Vol. 10 (november 2022)  
Detailed record - Creative Commons

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