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1.
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11 p, 1.2 MB |
Repair of Aortic Regurgitation in Young Adults : Sooner Rather Than Later
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Barradas-Pires, Ana (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Merás, Pablo (Hospital Universitario La Paz (Madrid)) ;
Constantine, Andrew (Imperial College London) ;
Costola, Giulia (Guy's and St Thomas' NHS Foundation Trust) ;
de la Cal, Teresa Segura (Hospital 12 de Octubre (Madrid)) ;
Rafiq, Isma (Guy's and St Thomas' NHS Foundation Trust) ;
Kempny, Aleksander (Imperial College London) ;
Li, Wei (Imperial College London) ;
Babu-Narayan, Sonya V. (Imperial College London) ;
Hoschtitzky, J. Andreas (Guy's and St Thomas' NHS Foundation Trust) ;
Gatzoulis, Michael A. (Imperial College London) ;
Rubio, Antonio Martinez (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Dimopoulos, Konstantinos (Imperial College London)
Establishing surgical criteria for aortic valve replacement (AVR) in severe aortic regurgitation in young adults is challenging due to the lack of evidence-based recommendations. We studied indications for AVR in young adults with severe aortic regurgitation and their outcomes, as well as the relationship between presurgical echocardiographic parameters and postoperative left ventricular (LV) size, function, clinical events, and valve-related complications. [...]
2023 -  10.1161/JAHA.122.029251
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 12 (september 2023)
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2.
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7 p, 467.1 KB |
Quality of care assessment and improvement in aortic stenosis - rationale and design of a multicentre registry (IMPULSE)
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Frey, Norbert (University of Kiel) ;
Steeds, Richard P. (University of Birmingham) ;
Serra, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Schulz, Eberhard (University Clinic Mainz) ;
Baldus, Stephan (Heart Center of the University Clinic Cologne) ;
Lutz, Matthias (University of Kiel) ;
Pohlmann, Christiane (Institute for Pharmacology and Preventive Medicine) ;
Kurucova, Jana (Edwards Lifesciences) ;
Bramlage, Peter (Institute for Pharmacology and Preventive Medicine) ;
Messika-Zeitoun, David (Bichat Hospital) ;
Universitat Autònoma de Barcelona
Severe aortic stenosis (AS) is a common, serious valve disease in which no effective medical therapy is available and, if not treated by intervention, has a 5-year survival of only 40-60%. Despite the availability of guidelines supporting the effective use of surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) to treat the majority of these patients, adherence to these guidelines in clinical practice is still unsatisfactory. [...]
2017 - 10.1186/s12872-016-0439-4
BMC Cardiovascular disorders, Vol. 17 Núm. 1 (may 2017) , p. 5
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3.
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16 p, 1.5 MB |
Facilitated Data Relay and Effects on Treatment of Severe Aortic Stenosis in Europe
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Steeds, Richard P. (University of Birmingham) ;
Lutz, Matthias (University of Kiel) ;
Thambyrajah, Jeetendra (James Cook Hospital) ;
Serra Peñaranda, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Schulz, Eberhard (University Clinic Mainz) ;
Maly, Jiri (Charles University) ;
Aiello, Marco (Foundation IRCCS Policlinico S.Matteo) ;
Rudolph, Tanja K. (University of Cologne Heart Center) ;
Lloyd, Guy (St Bartholomew's Hospital) ;
Bortone, Alessandro Santo (University of Bari) ;
Hauptmann, Karl Eugen (Krankenhaus der Barmherzigen Brüder Trier) ;
Clerici, Alberto (University of Turin) ;
Delle-Karth, Georg (Hietzing Hospital) ;
Rieber, Johannes (University of Munich) ;
Indolfi, Ciro (University Magna Graecia) ;
Mancone, Massimo (Sapienza University of Rome) ;
Belle, Loic (Centre Hospital d'Annecy) ;
Lauten, Alexander (University Heart Center & Charité) ;
Arnold, Martin (University Hospital) ;
Bouma, Berto J. (University of Amsterdam) ;
Deutsch, Cornelia (Institute for Pharmacology and Preventive Medicine) ;
Kurucova, Jana (Edwards Lifesciences) ;
Thoenes, Martin (Edwards Lifesciences) ;
Bramlage, Peter (Institute for Pharmacology and Preventive Medicine) ;
Frey, Norbert (University of Kiel) ;
Messika-Zeitoun, David (University of Ottawa Heart Institute) ;
Universitat Autònoma de Barcelona
Many patients with severe aortic stenosis are referred late with advanced symptoms or inappropriately denied intervention. The objective was to investigate whether a structured communication to referring physicians (facilitated data relay) might improve the rate and timeliness of intervention. [...]
2019 - 10.1161/JAHA.119.013160
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 8 Núm. 19 (january 2019) , p. e013160
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4.
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11 p, 1.3 MB |
Assessment of Platelet REACtivity After Transcatheter Aortic Valve Replacement : The REAC-TAVI Trial
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Jimenez Diaz, Victor Alfonso (Hospital Álvaro Cunqueiro (Vigo)) ;
Tello-Montoliu, Antonio (Centro de Investigación en Red de Enfermedades Cardiovasculares) ;
Moreno, Raul (Hospital Universitario La Paz (Madrid)) ;
Cruz Gonzalez, Ignacio (Hospital Universitario de Salamanca) ;
Baz Alonso, Jose Antonio (Hospital Álvaro Cunqueiro (Vigo)) ;
Romaguera, Rafael (Hospital Universitari de Bellvitge) ;
Molina Navarro, Eduardo (Hospital Universitario Virgen de las Nieves (Granada)) ;
Juan Salvadores, Pablo (Fundación Biomédica Galicia Sur) ;
Paredes Galan, Emilio (Hospital Álvaro Cunqueiro (Vigo)) ;
De Miguel-Castro, Antonio (Hospital Álvaro Cunqueiro (Vigo)) ;
Bastos Fernandez, Guillermo (Hospital Álvaro Cunqueiro (Vigo)) ;
Ortiz Saez, Alberto (Hospital Álvaro Cunqueiro (Vigo)) ;
Fernandez Barbeira, Saleta (Hospital Álvaro Cunqueiro (Vigo)) ;
Raposeiras Roubin, Sergio (Hospital Álvaro Cunqueiro (Vigo)) ;
Ocampo Miguez, Juan (Hospital Álvaro Cunqueiro (Vigo)) ;
Serra Peñaranda, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Valdes Chavarri, Mariano (Centro de Investigación en Red de Enfermedades Cardiovasculares) ;
Cequier, Ángel (Hospital Universitari de Bellvitge) ;
Calvo Iglesias, Francisco (Hospital Álvaro Cunqueiro (Vigo)) ;
Iñiguez Romo, Andrés (Centro de Investigación en Red de Enfermedades Cardiovasculares) ;
Universitat Autònoma de Barcelona
The REAC-TAVI (Assessment of platelet REACtivity after Transcatheter Aortic Valve Implantation) trial enrolled patients with aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) pre-treated with aspirin + clopidogrel, aimed to compare the efficacy of clopidogrel and ticagrelor in suppressing high platelet reactivity (HPR) after TAVI. [...]
2019 - 10.1016/j.jcin.2018.10.005
JACC: Cardiovascular Interventions, Vol. 12 Núm. 1 (14 2019) , p. 22-32
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5.
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7 p, 610.3 KB |
Impact of selected comorbidities on the presentation and management of aortic stenosis
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Rudolph, Tanka K. (Ruhr-University of Bochum) ;
Messika-Zeitoun, David (University of Ottawa Heart Institute) ;
Frey, Norbert (University of Kiel) ;
Thambyrajah, Jeetendra (James Cook University Hospital) ;
Serra, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Schulz, Eberhard (AKH Celle) ;
Maly, Jiri (Charles University) ;
Aiello, Marco (Foundation IRCCS Policlinico S.Matteo) ;
Lloyd, Guy (St Bartholomew's Hospital) ;
Bortone, Alessandro Santo (University of Bari) ;
Clerici, Alberto (University of Turin) ;
Delle-Karth, Georg (Hietzing Hospital) ;
Rieber, Johannes (University of Munich) ;
Indolfi, Ciro (Magna Graecia University) ;
Mancone, Massimo (Sapienza University of Rome) ;
Belle, Loic (Centre Hospital d'Annecy) ;
Lauten, Alexander (University Heart Center and Charité) ;
Arnold, Martin (University of Erlangen) ;
Bouma, Berto J. (University of Amsterdam) ;
Lutz, Matthias (University of Kiel) ;
Deutsch, Cornelia (Institute for Pharmacology and Preventive Medicine) ;
Kurucova, Jana (Edwards Lifesciences) ;
Thoenes, Martin (Edwards Lifesciences) ;
Bramlage, Peter (Institute for Pharmacology and Preventive Medicine) ;
Steeds, Richard (University of Birmingham) ;
Universitat Autònoma de Barcelona
Contemporary data regarding the impact of comorbidities on the clinical presentation and management of patients with severe aortic stenosis (AS) are scarce. Prospective registry of severe patients with AS across 23 centres in nine European countries. [...]
2020 - 10.1136/openhrt-2020-001271
Open Heart, Vol. 7 Núm. 2 (23 2020) , p. e001271
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9 p, 1.2 MB |
Importance of Tricuspid Regurgitation Velocity Threshold in Risk Assessment of Pulmonary Hypertension-Long-Term Outcome of Patients Submitted to Aortic Valve Replacement
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Garcia-Ribas, Cora (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ble, Mireia (Hospital del Mar (Barcelona, Catalunya)) ;
Gómez, Miquel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Mas-Stachurska, Aleksandra (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Cladellas Capdevila, Mercè (Universitat Autònoma de Barcelona. Departament de Medicina)
Background: The upper physiological threshold for tricuspid regurgitation velocity (TRV) of 2. 8 m/s proposed by the Pulmonary Hypertension (PH) guidelines had been questioned. The aim of this study was to evaluate the prognostic significance of preoperative PH in patients with aortic stenosis, long-term after valve replacement, using two different TRV thresholds (2. [...]
2021 - 10.3389/fcvm.2021.720643
Frontiers in Cardiovascular Medicine, Vol. 8 (november 2021)
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5 p, 1.0 MB |
Aortic Sinus Contrast Retention During TAVR : A Warning Sign Preceding a Potential Thrombotic Complication
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Asmarats, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Li, Chi Hion (Institut d'Investigació Biomèdica Sant Pau) ;
Millán, Xavier (Institut d'Investigació Biomèdica Sant Pau) ;
Menduiña, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Fernández-Peregrina, Esefanía (Institut d'Investigació Biomèdica Sant Pau) ;
Gutiérrez-Alonso, Lola (Institut d'Investigació Biomèdica Sant Pau) ;
Torres, Mario (Institut d'Investigació Biomèdica Sant Pau) ;
Serra, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Arzamendi, Dabit (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Sinus contrast material retention after transcatheter aortic valve replacement (TAVR) is a rare phenomenon that may reflect an increased risk for thrombotic complications. We present 3 cases of persistent contrast agent retention in the sinus of Valsalva during the TAVR procedure that portend the occurrence of embolic stroke or bioprosthetic valve thrombosis. [...]
2022 - 10.1016/j.jaccas.2022.03.031
JACC Case Reports, Vol. 4 Núm. 11 (january 2022) , p. 666-670
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9.
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10 p, 623.8 KB |
Clinical outcomes after implantation of a sutureless aortic bioprosthesis with concomitant mitral valve surgery : the SURE-AVR registry
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Baghai, M. ;
Glauber, M. (U.O. Cardiochirurgia Mininvasiva. Istituto Clinico Sant'Ambrogio) ;
Fontaine, R. (Chirurgie Cardiaque CHR Namur) ;
Castillo, J.C. (Cirugía Cardiaca. Hospital Juan Canalejo) ;
Walker, A.H. (Cardiothoracic Surgery. Blackpool Teaching Hospitals NHS Foundation Trust) ;
Livi, U. (Cardiochirurgia. Az. Osp. Univ. S. Maria della Misericordia) ;
Montiel, José (Institut d'Investigació Biomèdica Sant Pau) ;
Royse, A. (Cardiovascular department. The University of Melbourne) ;
Bisleri, G. (Division of Cardiac Surgery. University of Toronto) ;
Pacini, D. (Cardiochiurgia. Policlinico Sant'Orsola) ;
Argano, V. (U.O.C. Cardiochirurgia. AOU Policlinico "Paolo Giaccone") ;
Roumy, A. (Service de chirurgie cardio-vasculaire. Centre Hospitalier Universitaire Vaudois) ;
Asimakopoulos, G. (Heart Surgery. Royal Brompton Hospital) ;
Solinas, M. (U.O.C Cardiochirurgia Adulti. Ospedale del Cuore G. Pasquinucci. Fondazione Toscana Fabriele Monasterio) ;
Baghai, M. ;
Padró Fernández, José María
Background: Early treatment of aortic valve stenosis is recommended in eligible symptomatic patients with severe aortic valve stenosis who would otherwise have a poor prognosis. The sutureless aortic valve bioprosthesis offers an alternative to standard aortic valve replacement with a sutured valve, but limited data are available in patients who have undergone multiple valve procedures involving the new, sutureless technology. [...]
2021 - 10.1186/s13019-021-01523-w
Journal of Cardiothoracic Surgery, Vol. 16 Núm. 1 (december 2021) , p. 154
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21 p, 5.9 MB |
Oxidative Stress in Structural Valve Deterioration : A Longitudinal Clinical Study
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Galiñanes, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Casós, Kelly (Hospital Universitari de Bellvitge) ;
Blasco-Lucas, Arnau (Hospital Universitari de Bellvitge) ;
Permanyer, Eduard (Centro Médico Teknon) ;
Máñez, Rafael (Hospital Universitari de Bellvitge) ;
Le Tourneau, Thierry (Université de Nantes) ;
Barquinero, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Schwartz, Simon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bottio, Tomaso (University Hospital of Padova (Pàdua, Itàlia)) ;
Roussel, Jean Christian (CHU de Nantes) ;
Fellah-Hebia, Imen (CHU de Nantes) ;
Sénage, Thomas (Université de Nantes) ;
Evangelista Masip, Arturo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Badano, Luigi P. (San Luca Hospital(Itàlia)) ;
Ruiz-Majoral, Alejandro (Hospital Universitari de Bellvitge) ;
Galli, Cesare (Avantea and Fondazione Avantea Onlus (Itàlia)) ;
Padler-Karavani, Vered (Tel Aviv University) ;
Soulillou, Jean-Paul (Centre Hospitalier Universitaire de Nantes) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Cozzi, Emanuele (University Hospital of Padova (Pàdua, Itàlia)) ;
Costa, Cristina (Hospital Universitari de Bellvitge) ;
Universitat Autònoma de Barcelona
The cause of structural valve deterioration (SVD) is unclear. Therefore, we investigated oxidative stress markers in sera from patients with bioprosthetic heart valves (BHVs) and their association with SVD. [...]
2022 - 10.3390/biom12111606
Biomolecules, Vol. 12 (october 2022)
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