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1.
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11 p, 3.4 MB |
An interventional nationwide surveillance program lowers postoperative infection rates in elective colorectal surgery. A cohort study (2008-2019)
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Arroyo-Garcia, Nares (Universitat Internacional de Catalunya) ;
Badia, Josep M (Universitat Internacional de Catalunya) ;
Vázquez Fariñas, Ana (Universitat Autònoma de Barcelona) ;
Pera, Miguel (Hospital del Mar (Barcelona, Catalunya)) ;
Parés, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Limón, Enric (Universitat de Barcelona) ;
Almendral, Alexander (VINCat Program) ;
Piriz, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Pomar, Virginia (Institut d'Investigació Biomèdica Sant Pau) ;
López-Contreras, Joaquín (Institut d'Investigació Biomèdica Sant Pau) ;
Díez-García, C (Institut d'Investigació Biomèdica Sant Pau) ;
Fraccalvieri, Domenico (Hospital Universitari de Bellvitge) ;
Pujol, Miquel (Hospital Universitari de Bellvitge)
Colorectal surgery is associated with the highest rate of surgical site infection (SSI). This study analyses the effectiveness of an interventional surveillance program on SSI rates after elective colorectal surgery. [...]
2022 -  10.1016/j.ijsu.2022.106611
International journal of surgery, Vol. 102 (june 2022) , p. 106611
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2.
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15 p, 767.1 KB |
Leveraging a nationwide infection surveillance program to implement a colorectal surgical site infection reduction bundle : a pragmatic, prospective, and multicenter cohort study
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Badia, Josep M. (Universitat Internacional de Catalunya) ;
Arroyo-Garcia, Nares (Universitat Internacional de Catalunya) ;
Vázquez Fariñas, Ana (Universitat Autònoma de Barcelona. Servei d'Estadística Aplicada) ;
Almendral, Alexander (VINCat (Programa)) ;
Gomila, Aina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fraccalvieri, Domenico (Hospital Universitari de Bellvitge) ;
Parés, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Abad-Torrent, Ana (Hospital Universitari Vall d'Hebron) ;
Pascual Damieta, Marta (Hospital del Mar (Barcelona, Catalunya)) ;
Solís-Peña, Alejandro (Hospital Universitari Vall d'Hebron) ;
Puig-Asensio, Mireia (Instituto de Salud Carlos III) ;
Pera, Miguel (Hospital del Mar (Barcelona, Catalunya)) ;
Gudiol, Francesc (VINCat (Programa)) ;
Limón, Enric (Universitat de Barcelona) ;
Pujol, Miquel (VINCat (Programa))
Pragmatic interventional study to analyze the implementation and outcomes of a colorectal surgery care bundle within a nationwide quality improvement program. The bundle consisted of antibiotic prophylaxis, oral antibiotic prophylaxis (OAP), mechanical bowel preparation, laparoscopy, normothermia, and a wound retractor. [...]
2023 - 10.1097/JS9.0000000000000277
International journal of surgery, Vol. 109 (march 2023) , p. 737-751
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3.
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18 p, 1.8 MB |
Serum DNA methylome of the colorectal cancer serrated pathway enables non-invasive detection
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Gallardo-Gómez, María (Universidade de Vigo) ;
Costas-Ríos, Lara (Universidade de Vigo) ;
García-Prieto, Carlos A (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Álvarez-Rodríguez, Lara (Universidade de Vigo) ;
Bujanda, Luis (Universidad del País Vasco) ;
Barrero, Maialen (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Castells, Antoni (Hospital Clínic i Provincial de Barcelona) ;
Balaguer, Francesc (Hospital Clínic i Provincial de Barcelona) ;
Jover, Rodrigo (Universidad Miguel Hernández, Alicante) ;
Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Tardío Baiges, Antoni (Instituto de Investigación Biomédica Galicia Sur) ;
González-Carreró Fojón, Joaquín (Instituto de Investigación Biomédica Galicia Sur) ;
Cubiella, Joaquín (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Ourense) ;
De Chiara, Loretta (Universidade de Vigo)
The clinical relevance of the colorectal cancer serrated pathway is evident, but the screening of serrated lesions remains challenging. We aimed to characterize the serum methylome of the serrated pathway and to evaluate circulating cell-free DNA (cfDNA) methylomes as a potential source of biomarkers for the non-invasive detection of serrated lesions. [...]
2023 - 10.1002/1878-0261.13573
Molecular Oncology, 2023
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4.
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17 p, 4.7 MB |
Serum methylation of GALNT9, UPF3A, WARS, and LDB2 as noninvasive biomarkers for the early detection of colorectal cancer and advanced adenomas
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Gallardo-Gómez, María (Universidade de Vigo) ;
Rodríguez-Girondo, Mar (Department of Medical Statistics and Bioinformatics. Leiden University Medical Centre) ;
Planell, Núria (Universidad Pública de Navarra) ;
Moran, Sebastián (Institut d'Investigació Biomèdica de Bellvitge) ;
Bujanda, Luis (Universidad del País Vasco. Instituto de Investigación Sanitaria Biodonostia) ;
Etxart, Ane (Department of Surgery. Hospital Universitario Donostia) ;
Castells, Antoni (Universitat de Barcelona) ;
Balaguer, Francesc (Universitat de Barcelona) ;
Jover, Rodrigo (Servicio de Medicina Digestiva. Universidad Miguel Hernández) ;
Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Cubiella, Joaquin (Department of Gastroenterology. Complexo Hospitalario Universitario de Ourense. Instituto de Investigación Biomédica Galicia Sur. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Gómez-Cabrero, David (Mucosal & Salivary Biology Division. King's College London Dental Institute) ;
De Chiara, Loretta (Galicia Sur Health Research Institute) ;
Universitat Autònoma de Barcelona
Background: Early detection has proven to be the most effective strategy to reduce the incidence and mortality of colorectal cancer (CRC). Nevertheless, most current screening programs suffer from low participation rates. [...]
2023 - 10.1186/s13148-023-01570-1
Clinical Epigenetics, Vol. 15 Núm. 1 (december 2023) , p. 157
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5.
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21 p, 9.8 MB |
Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors
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Mira, Alessia (Candiolo Cancer Institute) ;
Morello, Virginia (University of Torino Medical School) ;
Céspedes, María Virtudes (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Perera, Timothy (OCTIMET Oncology Ltd) ;
Comoglio, Paolo M. (Candiolo Cancer Institute) ;
Mangues, Ramon 1957- (Institut d'Investigació Biomèdica Sant Pau) ;
Michieli, Paolo (University of Torino Medical School) ;
Universitat Autònoma de Barcelona
The role of paracrine Hepatocyte Growth Factor (HGF) in the resistance to angiogenesis inhibitors (AIs) is hidden in xenograft models because mouse HGF fails to fully activate human MET. To uncover it, we compared the efficacy of AIs in wild-type and human HGF knock-in SCID mice bearing orthotopic human colorectal tumors. [...]
2017 - 10.18632/oncotarget.16942
Oncotarget, Vol. 8 Núm. 24 (2017) , p. 38193-38213
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6 p, 2.0 MB |
The colon does not reach! A technical note with tricks to avoid colorectal anastomoses under tension
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Dalmau, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Marti-Gallostra, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pellino, Gianluca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Espin-Basany, Eloy (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Armengol Carrasco, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona.
Departament de Cirurgia
Aim: We describe two options for colorectal anastomosis suitable in cases when the colon would reach the pelvis under tension. Method: Deloyers procedure and the retro-ileal colorectal anastomosis are presented, focusing on practical tips and tricks to perform them. [...]
2024 - 10.1111/codi.16865
Colorectal Disease, Vol. 26, Num. 3 (march 2024) , p. 564-569
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13 p, 1.8 MB |
Lymph Node Molecular Analysis with OSNA Enables the Identification of pT1 CRC Patients at Risk of Recurrence : A Multicentre Study
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Saez de Gordoa, Karmele (Hospital Clínic i Provincial de Barcelona) ;
Rodrigo-Calvo, Maria Teresa (Hospital Clínic i Provincial de Barcelona) ;
Archilla, Ivan (Hospital Clínic i Provincial de Barcelona) ;
Lopez-Prades, Sandra (Hospital Clínic i Provincial de Barcelona) ;
Díaz, Alba (Hospital Clínic i Provincial de Barcelona) ;
Tarragona, Jordi (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Machado, Isidro (Centro de Investigación Biomédica en Red en Cancer (CIBERONC)) ;
Ruiz Martín, Juan (Virgen de la Salud Hospital, Toledo) ;
Zaffalon, Diana (Consorci Sanitari de Terrassa) ;
Daca-Alvarez, Maria (Hospital Clínic i Provincial de Barcelona) ;
Pellisé, Maria (Hospital Clínic i Provincial de Barcelona) ;
Camps, Jordi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Cuatrecasas, Miriam (Hospital Clínic i Provincial de Barcelona)
Early-stage colorectal carcinoma (CRC)-pT1-is a therapeutic challenge and presents some histological features related to lymph node metastasis (LNM). A significant proportion of pT1 CRCs are treated surgically, resulting in a non-negligible surgical-associated mortality rate of 1. [...]
2023 - 10.3390/cancers15225481
Cancers, Vol. 15 (november 2023)
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9 p, 969.5 KB |
SEOM clinical guidelines for diagnosis and treatment of metastatic colorectal cancer (2018)
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Gómez-España, M.A. (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Gallego, J. (Hospital General Universitario de Elche) ;
González-Flores, E. (Hospital Universitario Virgen de las Nieves (Granada)) ;
Maurel, Joan (Hospital Clínic i Provincial de Barcelona) ;
Páez, David (Institut d'Investigació Biomèdica Sant Pau) ;
Sastre, J. (Hospital Clínico San Carlos (Madrid)) ;
Aparicio, J. (Hospital Universitari i Politècnic La Fe (València)) ;
Benavides Orgaz, Manuel (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Feliu, J. (Hospital Universitario La Paz (Madrid)) ;
Vera, R. (Complejo Hospitalario de Navarra) ;
Universitat Autònoma de Barcelona
Colorectal cancer (CRC) is the second cause of cancer death in Spain, the objective of this guide published by the Spanish Society of Medical Oncology is to develop a consensus for the diagnosis and management of metastatic disease. [...]
2019 - 10.1007/s12094-018-02002-w
Clinical & Translational Oncology, Vol. 21 Núm. 1 (25 2019) , p. 46-54
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11 p, 987.9 KB |
Participants' satisfaction with colorectal cancer screening programs : A systematic review
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Selva, A. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Mosconi, Giansanto (University of Pavia) ;
Cacitti, Stefano (Health Protection Agency of Pavia) ;
Odone, Anna (University of Pavia) ;
Pylkkanen, Liisa (University of Turku) ;
Solà, Ivan (Institut d'Investigació Biomèdica Sant Pau) ;
Torà, Núria (Althaia Xarxa Assistencial Universitària de Manresa) ;
Russo, Sara (University of Pavia) ;
Cadum, Ennio (Health Protection Agency of Pavia) ;
Deandrea, Silvia (Health Protection Agency of Pavia) ;
Universitat Autònoma de Barcelona
Since satisfaction with cancer screening experience can increase adherence to programs and contribute to reduce morbidity and mortality, its assessment is crucial for programs' effectiveness. Our aim was to conduct a systematic review about satisfaction of participants with organized colorectal cancer screening. [...]
2023 - 10.1016/j.ypmed.2023.107706
Preventive Medicine, Vol. 175 (october 2023) , p. 107706
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11 p, 1.2 MB |
Correlation of recist, computed tomography morphological response, and pathological regression in hepatic metastasis secondary to colorectal cancer : The avamet study
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Vera, Ruth (Instituto de investigaciones Sanitarias de Navarra (IdISNA)) ;
Gómez, María Luisa (Complejo Hospitalario de Navarra) ;
Ayuso Colella, Juan Ramón (Hospital Clínic i Provincial de Barcelona) ;
Figueras, Joan (Hospital Universitari de Girona Doctor Josep Trueta) ;
García-Alfonso, Pilar (Hospital General Universitario Gregorio Marañón) ;
Martínez, Virginia (Hospital Universitario La Paz (Madrid)) ;
Lacasta, Adelaida (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Ruiz-casado, Ana (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Safont, María José (Hospital General Universitario de Valencia) ;
Aparicio Urtasun, Jorge (Hospital Universitari i Politècnic La Fe (València)) ;
Campos, Juan Manuel (Hospital Arnau de Vilanova (València)) ;
Cámara, Juan Carlos (Hospital Universitario Fundación Alcorcón) ;
Martín-Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Montagut Viladot, Clara (Hospital del Mar (Barcelona, Catalunya)) ;
Pericay, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Vieitez, Jose María (Hospital Universitario Central de Asturias) ;
Falcó, Esther (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Jorge, Mónica (Hospital Xeral Cíes) ;
Marín, Miguel (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Salgado, Mercedes (Complejo Hospitalario de Ourense) ;
Viúdez, Antonio (Instituto de investigaciones Sanitarias de Navarra (IdISNA)) ;
Universitat Autònoma de Barcelona
The prospective phase IV AVAMET study was undertaken to correlate response evaluation criteria in solid tumors (RECIST)-defined response rates with computed tomography-based morphological criteria (CTMC) and pathological response after liver resection of colorectal cancer metastases. [...]
2020 - 10.3390/cancers12082259
Cancers, Vol. 12 Núm. 8 (august 2020) , p. 1-12
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