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14 p, 1.0 MB |
Pharmacological treatments and medication-related problems in nursing homes in Catalonia : a multidisciplinary approach
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Anderssen-Nordahl, Emilie (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez-Arcilla Rosanas, Margarita (Hospital Universitari Vall d'Hebron) ;
Bosch Ferrer, Montserrat (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Sabaté Gallego, Mònica (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Fernández-Liz, Eladio (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
San-José, Antonio (Hospital Universitari Vall d'Hebron) ;
Barceló-Colomer, Maria Estrella (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Background: Aging correlates with increased frailty, multi-morbidity, and chronic diseases. Furthermore, treating the aged often entails polypharmacy to achieve optimal disease management, augmenting medication-related problems (MRPs). [...]
2024 -  10.3389/fphar.2024.1320490
Frontiers in Pharmacology, Vol. 15 (march 2024) ,
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12 p, 1.3 MB |
The Need for the Closer Monitoring of Novel Drugs in MS : A Siponimod Retrospective Cohort Study (Realhes Study)
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Sancho-López, Arantxa (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Ruiz-Antorán, Belén (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Iglesias Hernangómez, Teresa (Hospital Universitario Clínico San Carlos (Madrid)) ;
Ramírez-García, Almudena (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Gómez-Estévez, Irene (Universidad Complutense de Madrid) ;
Sanabria-Cabrera, Judith (Plataforma ISCIII de Investigación Clínica) ;
Llop Rius, Roser (Hospital Universitari de Bellvitge) ;
Pedrós, Consuelo (Hospital General Universitario de Valencia) ;
Campodonico, Diana (Hospital Universitario de la Princesa (Madrid)) ;
Jiménez-Jorge, Silvia (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
García Luque, Amelia (University of Alcalá (IRYCIS)) ;
Costa-Frossard, Lucienne (Hospital Universitario Ramón y Cajal (Madrid)) ;
Montané Esteva, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Aldea-Perona, Ana (Hospital del Mar (Barcelona, Catalunya)) ;
Téllez Lara, Nieves (Hospital Clínico Universitario de Valladolid) ;
Bosch Ferrer, Montserrat (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez Jiménez, Consuelo (Complejo Hospitalario Universitario e Canarias) ;
Bonilla-Toyos, Elvira (Plataforma ISCIII de Investigación Clínica) ;
Sabín Muñoz, Julia (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Avendaño Sola, Cristina (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Blasco Quilez, María Rosario (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Universitat Autònoma de Barcelona
Severe cases of lymphopenia have been reported during siponimod clinical trials, which may negatively impact its benefit/risk profile. We aimed to evaluate the incidence of lymphopenia following the initiation of siponimod treatment in clinical practice. [...]
2023 - 10.3390/jcm12206471
Journal of clinical medicine, Vol. 12 (october 2023)
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50 p, 7.5 MB |
Pseudomonas fitomaticsae sp. nov., isolated at Marimurtra Botanical Garden in Blanes, Catalonia, Spain
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Atanasov, Kostadin E. (Centre de Recerca en Agrigenòmica) ;
Miñana-Galbis, David (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Cornadó, Deborah (Leitat Technological Center (Terrassa)) ;
Serpico, Annabel (Leitat Technological Center (Terrassa)) ;
Sánchez, Guiomar (Leitat Technological Center (Terrassa)) ;
Bosch, Montserrat (Leitat Technological Center (Terrassa)) ;
Ferrer, Albert (Centre de Recerca en Agrigenòmica) ;
Altabella Artigas, Teresa (Centre de Recerca en Agrigenòmica)
In the framework of the research project called fitomatics, we have isolated and characterized a bacterial plant-endophyte from the rhizomes of Iris germanica, hereafter referred to as strain FIT81. The bacterium is Gram negative, rod-shaped with lophotrichous flagella, and catalase-and oxidase-positive. [...]
2022 - 10.1099/IJSEM.0.005557
International Journal of Systematic and Evolutionary Microbiology, Vol. 72, Issue 10 (October 2022) , art. 5557
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11 p, 274.2 KB |
Safety of Drugs Used during the First Wave of COVID-19 : A Hospital-Registry-Based Study
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Aguilera, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Danés Carreras, Immaculada (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Guillén, Elena (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Vimes, Alba (Hospital Universitari Vall d'Hebron) ;
Bosch Ferrer, Montserrat (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cereza García, Gloria (Hospital Universitari Vall d'Hebron) ;
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Campos Varela, Isabel (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Miarons, Marta (Hospital Universitari Vall d'Hebron) ;
Mestre Torres, Jaume (Hospital Universitari Vall d'Hebron) ;
Agustí Escasany, M. Antònia (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The emergency of the coronavirus disease 2019 (COVID-19) pandemic led to the off-label use of drugs without data on their toxicity profiles in patients with COVID-19, or on their concomitant use. Patients included in the COVID-19 Patient Registry of a tertiary hospital during the first wave were analyzed to evaluate the adverse drug reactions (ADRs) with the selected treatments. [...]
2022 - 10.3390/diagnostics12071612
Diagnostics, Vol. 12 Núm. 7 (july 2022) , p. 1612
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30 p, 2.6 MB |
Pseudomonas germanica sp. nov., isolated from Iris germanica rhizomes
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Atanasov, Kostadin E. (Centre de Recerca en Agrigenòmica) ;
Miñana-Galbis, David (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Gallego, Julia (LEITAT Technological Center (Barcelona)) ;
Serpico, Annabel (LEITAT Technological Center (Barcelona)) ;
Bosch, Montserrat (LEITAT Technological Center (Barcelona)) ;
Altabella Artigas, Teresa (Centre de Recerca en Agrigenòmica) ;
Ferrer, Albert (Centre de Recerca en Agrigenòmica)
Through bacterial plant-endophyte extraction from rhizomes of Iris germanica plant, a Gram-stain-negative, aerobic, catalase- and oxidase-positive gammaproteobacterial strain, referred to as FIT28T, was isolated. [...]
2022 - 10.1099/ijsem.0.005268
International Journal of Systematic and Evolutionary Microbiology, Vol. 72, Issue 3 (March 2022)
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164 p, 1.8 MB |
Identificació de reaccions adverses greus a nous medicaments
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Bosch Ferrer, Montserrat ;
Laporte Rosselló, Joan-Ramón, dir. ;
Universitat Autònoma de Barcelona.
Departament de Farmacologia, de Terapèutica i de Toxicologia
Des dels anys seixanta, la farmacovigilància s'ha basat en la notificació de casos. Des dels vuitanta, els estudis observacionals han identificat nous efectes adversos de medicaments amb fort impacte de salut pública, i n'han quantificat el risc. [...]
In the 1960's, pharmacovigilance was mainly based on case reports. Since the 1980's, observational studies helped to identify new adverse drug reactions which have a big impact on public health, and they have also quantified their risk. [...]
[Barcelona] : Universitat Autònoma de Barcelona, 2016
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12 p, 769.2 KB |
Assessing the role of tandem repeats in shaping the genomic architecture of great apes
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Farré, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Bosch i Gallego, Montserrat (Institut de Recerca i Tecnologia Agroalimentàries) ;
López Giráldez, Francesc (Yale University. Department of Ecology and Evolutionary Biology) ;
Ponsà i Fontanals, Montserrat (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Background: Ancestral reconstructions of mammalian genomes have revealed that evolutionary breakpoint regions are clustered in regions that are more prone to break and reorganize. What is still unclear to evolutionary biologists is whether these regions are physically unstable due solely to sequence composition and/or genome organization, or do they represent genomic areas where the selection against breakpoints is minimal. [...]
2011 - 10.1371/journal.pone.0027239
PloS one, Vol. 6, Issue 11 (November 2011) , p. e27239
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