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1.
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8 p, 4.5 MB |
Peptide-based biosensing approaches for targeting breast cancer-derived exosomes
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da Fonseca Alves, Rafael (Universitat Autònoma de Barcelona. Departament de Química) ;
Pallarès-Rusiñol, Arnau (Universitat Autònoma de Barcelona. Departament de Química) ;
Rossi, Rosanna (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Martí, Mercè (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Rezende Vaz, Emilia (Universidade Estadual Paulista) ;
Gonçalves de Araújo, Thaise (Universidade Federal de Uberlândia) ;
Sotomayor, Maria (Universidade Federal de Uberlândia) ;
Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
Exosomes are nanovesicles present in all the biological fluids, making them attractive as non-invasive biomarkers for diseases like cancer, among many others. However, exosomes are complex to separate and detect, requiring comprehensive molecular characterization for their routine use in diagnostics. [...]
2024 -  10.1016/j.bios.2024.116211
Biosensors & bioelectronics, Vol. 255 (July 2024) , art. 116211
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2.
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9 p, 4.2 MB |
Unleashing inkjet-printed nanostructured electrodes and battery-free potentiostat for the DNA-based multiplexed detection of SARS-CoV-2 genes
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Rossetti, Marianna (Institut Català de Nanociència i Nanotecnologia) ;
Srisomwat, Chawin (Chulalongkorn University. Department of Chemistry) ;
Urban, Massimo (Universitat Autònoma de Barcelona) ;
Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia) ;
Maroli, Gabriel (Institut Català de Nanociència i Nanotecnologia) ;
Yaman Akbay, Hatice Gödze (Institut Català de Nanociència i Nanotecnologia) ;
Chailapakul, Orawon (Chulalongkorn University. Department of Chemistry) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
Following the global COVID-19 pandemic triggered by SARS-CoV-2, the need for rapid, specific and cost-effective point-of-care diagnostic solutions remains paramount. Even though COVID-19 is no longer a public health emergency, the disease still poses a global threat leading to deaths, and it continues to change with the risk of new variants emerging causing a new surge in cases and deaths. [...]
2024 - 10.1016/j.bios.2024.116079
Biosensors & bioelectronics, Vol. 250 (April 2024) , art. 116079
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3.
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9 p, 4.8 MB |
Biomimetic nanoplasmonic sensor for rapid evaluation of neutralizing SARS-CoV-2 monoclonal antibodies as antiviral therapy
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Batool, Razia (Institut Català de Nanociència i Nanotecnologia) ;
Soler Aznar, Maria (Institut Català de Nanociència i Nanotecnologia) ;
Colavita, Francesca (National Institute for Infectious Disease "L. Spallanzani") ;
Fabeni, Lavinia (National Institute for Infectious Disease "L. Spallanzani") ;
Matusali, Giulia (National Institute for Infectious Disease "L. Spallanzani") ;
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Monoclonal antibody (mAb) therapy is one of the most promising immunotherapies that have shown the potential to prevent or neutralize the effects of COVID-19 in patients at very early stages, with a few formulations recently approved by the European and American medicine agencies. [...]
2023 - 10.1016/j.bios.2023.115137
Biosensors & bioelectronics, Vol. 226 (April 2023) , art. 115137
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4.
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13 p, 2.1 MB |
Magnetic Bead Handling Using a Paper-Based Device for Quantitative Point-of-Care Testing
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Arias-Alpízar, Kevin (Hospital Universitari Vall d'Hebron) ;
Sánchez-Cano, Ana (Hospital Universitari Vall d'Hebron) ;
Prat-Trunas, Judit (Hospital Universitari Vall d'Hebron) ;
Sulleiro Igual, Elena (Hospital Universitari Vall d'Hebron) ;
Bosch-Nicolau, Pau (Hospital Universitari Vall d'Hebron) ;
Salvador, Fernando (Hospital Universitari Vall d'Hebron) ;
Oliveira-Souto, Inés (Hospital Universitari Vall d'Hebron) ;
Molina Romero, Israel (Hospital Universitari Vall d'Hebron) ;
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron) ;
Baldrich Rubio, Eva (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Microfluidic paper-based analytical devices (μPADs) have been extensively proposed as ideal tools for point-of-care (POC) testing with minimal user training and technical requirements. However, most μPADs use dried bioreagents, which complicate production, reduce device reproducibility and stability, and require transport and storage under temperature and humidity-controlled conditions. [...]
2022 - 10.3390/bios12090680
Biosensors, Vol. 12 (august 2022)
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5.
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28 p, 1.2 MB |
Electrocatalytic tuning of biosensing response through electrostatic or hydrophobic enzyme-graphene oxide interactions
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Baptista Pires, Luis Miguel (Institut Català de Nanociència i Nanotecnologia) ;
Pérez-López, Briza (Leitat Technological Center (Terrassa)) ;
Mayorga-Martinez, Carmen C. (Institut Català de Nanociència i Nanotecnologia) ;
Morales-Narváez, Eden (Institut Català de Nanociència i Nanotecnologia) ;
Domingo Marimon, Neus (Institut Català de Nanociència i Nanotecnologia) ;
Esplandiu Egido, Maria José (Institut Català de Nanociència i Nanotecnologia) ;
Alzina, Francesc (Institut Català de Nanociència i Nanotecnologia) ;
Sotomayor Torres, Clivia M. (Institut Català de Nanociència i Nanotecnologia) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
The effect of graphene oxidative grades upon the conductivity and hydrophobicity and consequently the influence on an enzymatic biosensing response is presented. The electrochemical responses of reduced graphene oxide (rGO) have been compared with the responses obtained from the oxide form (oGO) and their performances have been accordingly discussed with various evidences obtained by optical techniques. [...]
2014 - 10.1016/j.bios.2014.05.028
Biosensors & bioelectronics, Vol. 61 (Nov. 2014) , p. 655-662
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6.
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25 p, 6.0 MB |
A self-powered skin-patch electrochromic biosensor
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Santiago, Sara (Universitat Autònoma de Barcelona) ;
Río-Colín, Diego (Universidad del País Vasco) ;
Azizkhani, Haniyeh (Universitat Autònoma de Barcelona) ;
Aller Pellitero, Miguel (Johns Hopkins University School of Medicine) ;
Guirado López, Gonzalo (Universitat Autònoma de Barcelona) ;
del Campo, F. Javier (Institut de Microelectrònica de Barcelona)
One of the limitations of many skin-patch wearable sensors today is their dependence on silicon-based electronics, increasing their complexity and unit cost. Self-powered sensors, in combination with electrochromic materials, allow simplifying the construction of these devices, leading to powerful analytical tools that remove the need for external detection systems. [...]
2021 - 10.1016/j.bios.2020.112879
Biosensors & bioelectronics, Vol. 175 (March 2021) , art. 112879
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7.
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24 p, 1.8 MB |
Wearable and fully printed microfluidic nanosensor for sweat rate, conductivity, and copper detection with healthcare applications
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Yang, Qiuyue (Institut Català de Nanociència i Nanotecnologia) ;
Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia) ;
Abarintos, Vernalyn (Institut Català de Nanociència i Nanotecnologia) ;
Aroca, Miguel A. (Universidad de Los Andes. Departamento de Ingeniería Eléctrica e Ingeniería Electrónica) ;
Osma, Johann F. (Universidad de Los Andes. Departamento de Ingeniería Eléctrica e Ingeniería Electrónica) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia) ;
Universitat Autònoma de Barcelona
Wearables are becoming pervasive in our society, but they are still mainly based on physical sensors with just few optical and electrochemical exceptions. Sweat, amongst other body fluids, is easily and non-invasively accessible, abundant, and relatively poor of interfering species. [...]
2022 - 10.1016/j.bios.2022.114005
Biosensors & bioelectronics, Vol. 202 (April 2022) , art. 114005
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8.
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23 p, 7.2 MB |
Comparing nucleic acid lateral flow and electrochemical genosensing for the simultaneous detection of foodborne pathogens
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Ben Aissa Soler, Alejandra (Universitat Autònoma de Barcelona. Departament de Química) ;
Jara, José Juan (Universitat Autònoma de Barcelona. Departament de Química) ;
Sebastián Pérez, Rosa Maria (Universitat Autònoma de Barcelona. Departament de Química) ;
Vallribera Massó, Adelina (Universitat Autònoma de Barcelona. Departament de Química) ;
Campoy Sánchez, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
Due to the increasing need of rapid tests for application in low resource settings, WHO summarized their ideal features under the acronym ASSURED (Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment-free, Delivered to those who need it). [...]
2017 - 10.1016/j.bios.2016.08.046
Biosensors & bioelectronics, Vol. 88 (February 2017) , p. 265-272
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9.
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29 p, 1.4 MB |
Label-free and reagentless electrochemical genosensor based on graphene acid for meat adulteration detection
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Flauzino, J. M. R. (Institut Català de Nanociència i Nanotecnologia) ;
Nguyen, Emily P. (Institut Català de Nanociència i Nanotecnologia) ;
Yang, Qiuyue (Institut Català de Nanociència i Nanotecnologia) ;
Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia) ;
Panáček, David (Institut Català de Nanociència i Nanotecnologia) ;
Brito-Madurro, Ana G. (Federal University of Uberlândia. Institute of Biotechnology (Brazil)) ;
Madurro, João M. (Federal University of Uberlândia. Institute of Chemistry (Brazil)) ;
Bakandritsos, Aristides (VŠB-Technical University of Ostrava. Centre of Energy and Environmental Technologies. Nanotechnology Centre (Czech Republic)) ;
Otyepka, Michal (VŠB-Technical University of Ostrava. IT4Innovations (Czech Republic)) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
With the increased demand for beef in emerging markets, the development of quality-control diagnostics that are fast, cheap and easy to handle is essential. Especially where beef must be free from pork residues, due to religious, cultural or allergic reasons, the availability of such diagnostic tools is crucial. [...]
2022 - 10.1016/j.bios.2021.113628
Biosensors & bioelectronics, Vol. 195 (January 2022) , art. 113628
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10.
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10 p, 4.6 MB |
A plug, print & play inkjet printing and impedance-based biosensing technology operating through a smartphone for clinical diagnostics
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Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia) ;
Urban, Massimo (University of Trieste. Department of Chemical and Pharmaceutical Sciences) ;
Zhao, Lei (Institut Català de Nanociència i Nanotecnologia) ;
Yang, Qiuyue (Institut Català de Nanociència i Nanotecnologia) ;
De Carvalho Castro Silva, Cecilia (Institut Català de Nanociència i Nanotecnologia) ;
Bonaldo, Stefano (University of Padova. Department of Information Engineering) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Nguyen, Emily P. (Institut Català de Nanociència i Nanotecnologia) ;
Ortega, Gabriel (University of California Santa Barbara. Department of Chemistry and Biochemistry) ;
Fornasiero, Paolo (University of Trieste. Department of Chemical and Pharmaceutical Sciences) ;
Paccagnella, Alessandro (University of Padova. Department of Information Engineering) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
Simplicity is one of the key feature for the spread of any successful technological product. Here, a method for rapid and low-cost fabrication of electrochemical biosensors is presented. This "plug, print & play" method involves inkjet-printing even in an office-like environment, without the need of highly specialized expertise or equipment, guaranteeing an ultra-fast idea to (scaled) prototype production time. [...]
2022 - 10.1016/j.bios.2021.113737
Biosensors & bioelectronics, Vol. 196 (January 2022) , art. 113737
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