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7 p, 407.0 KB |
Description of stroke mimics after complete neurovascular assessment Estudio descriptivo de los stroke mimics después de un estudio neurovascular completo
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Avellaneda-Gómez, C. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodríguez Campello, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giralt Steinhauer, Eva. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gómez González, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Serra Martínez, M. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
de Ceballos Cerrajería, P. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Zabalza de Torres, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ois, Angel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Jiménez-Conde, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Roquer, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
Introduction: A considerable percentage of events initially diagnosed as ischaemic stroke have non-cerebrovascular causes; these are called stroke mimics (SM). Currently available evidence about these events is heterogeneous and comes from studies with small samples. [...]
2019 -  10.1016/j.nrl.2016.10.006
Neurología, Vol. 34 Núm. 1 (enero 2019) , p. 7-13
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8 p, 373.5 KB |
Subtype Specificity of Genetic Loci Associated With Stroke in 16 664 Cases and 32 792 Controls
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Traylor, M. (University of Cambridge) ;
Anderson, C. D. (Massachusetts General Hospital (Boston)) ;
Rutten-Jacobs, L. C. A. (Deutsche Zentrum für Neurodegenerative Erkrankungen) ;
Falcone, G. J. (Yale School of Medicine) ;
Comeau, Mary E. (Wake Forest University) ;
Ay, H. (Massachusetts General Hospital (Boston)) ;
Sudlow, C. L. M. (University of Edinburgh) ;
Xu, H. (University of Maryland School of Medicine) ;
Mitchell, B. D. (University of Maryland School of Medicine) ;
Cole, John W. (University of Maryland School of Medicine) ;
Rexrode, K. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Schmidt, Reinhold (Medizinische Universität Graz) ;
Grewal, R. P. (Seton Hall University) ;
Sacco, Ralph L. (Miller School of Medicine) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rundek, T. (Miller School of Medicine) ;
Rosand, J. (Massachusetts General Hospital (Boston)) ;
Dichgans, Martin. (Ludwig-Maximilians-Universität München) ;
Lee, J. M. (Washington University School of Medicine) ;
Langefeld, Carl D (Wake Forest University) ;
Kittner, S. J. (University of Maryland School of Medicine) ;
Markus, H. S. (University of Cambridge) ;
Woo, D. (University of Cincinnati) ;
Malik, R. (Ludwig-Maximilians-Universität München) ;
Universitat Autònoma de Barcelona
Background: Genome-wide association studies have identified multiple loci associated with stroke. However, the specific stroke subtypes affected, and whether loci influence both ischemic and hemorrhagic stroke, remains unknown. [...]
2019 - 10.1161/CIRCGEN.118.002338
Circulation. Genomic and precision medicine, Vol. 12 Núm. 7 (january 2019) , p. 307-314
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13 p, 1.4 MB |
Genome-wide association meta-analysis of functional outcome after ischemic stroke
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Söderholm, Martin (Skåne University Hospital (Suècia)) ;
Pedersen, Annie (Department of Clinical Neuroscience. Institute of Neuroscience and Physiology. Sahlgrenska Academy. University of Gothenburg) ;
Lorentzen, Erik (Sahlgrenska University Hospital (Suècia)) ;
Stanne, Tara M. (Institute of Biomedicine) ;
Bevan, Steve (Bioinformatics Core Facility. University of Gothenburg) ;
Olsson, Maja (Institute of Biomedicine) ;
Cole, John W. ;
Fernandez-Cadenas, Israel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Hankey, Graeme J. (Medical School. The University of Western Australia, Perth; Department of Neurology) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Jood, Katarina (Department of Clinical Genetics and Genomics) ;
Lee, Jin-Moo (Department of Neurology. Washington University School of Medicine, St. Louis, MO) ;
Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ;
Levi, Christopher R (School of Medicine and Public Health) ;
Mitchell, Braxton D. (Priority Research Centre for Stroke and Traumatic Brain Injury. University of Newcastle) ;
Norrving, Bo (Skåne University Hospital (Suècia)) ;
Rannikmäe, Kristiina (University of Maryland. Department of Medicine) ;
Rost, Natalia S. (Geriatric Research. Education. and Clinical Center. Veterans Affairs Medical Center) ;
Rosand, Jonathan (Massachusetts General Hospital (Boston)) ;
Rothwell, Peter M. (Broad Institute of MIT and Harvard) ;
Scott, Rodney (University of Virginia. Departments of Neurology and Health Evaluation Sciences) ;
Strbian, Daniel (Massachusetts General Hospital (Boston)) ;
Sturm, Jonathan W. (VIB. Center for Brain and Disease Research) ;
Sudlow, Cathie (University of Maryland. Department of Medicine) ;
Traylor, Matthew (University of Oxford. Nuffield Department of Clinical Neurosciences.) ;
Thijs, Vincent (University of Cambridge. Department of ClinicalNeurosciences) ;
Tatlisumak, Turgut (Stroke Division. Florey Institute for Neuroscience and Mental Health. University of Melbourne) ;
Woo, Daniel (Austin Health. Department of Neurology) ;
Worrall, Bradford B. (University of Cincinnati. Department of Neurology and Rehabilitation) ;
Maguire, Jane M. (HunterMedical Research Centre. PRC Stroke and Brain Injury) ;
Lindgren, Arne (Skåne University Hospital (Suècia)) ;
Jern, Christina (University of Lincoln. School of Life Sciences) ;
Universitat Autònoma de Barcelona
ObjectiveTo discover common genetic variants associated with poststroke outcomes using a genome-wide association (GWA) study. MethodsThe study comprised 6,165 patients with ischemic stroke from 12 studies in Europe, the United States, and Australia included in the GISCOME (Genetics of Ischaemic Stroke Functional Outcome) network. [...]
2019 - 10.1212/WNL.0000000000007138
Neurology, Vol. 92 Núm. 12 (19 2019) , p. E1271-E1283
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12 p, 544.9 KB |
Association of Apolipoprotein e with Intracerebral Hemorrhage Risk by Race/Ethnicity : A Meta-analysis
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Marini, Sandro (Massachusetts General Hospital (Boston)) ;
Crawford, Katherine (Massachusetts General Hospital (Boston)) ;
Morotti, A. (Fondazione Mondino IRCCS, Pavia) ;
Lee, M. J. (Massachusetts General Hospital (Boston)) ;
Pezzini, Alessandro (Università degli Studi di Brescia) ;
Moomaw, C. J. (University of Cincinnati) ;
Flaherty, M. L. (University of Cincinnati) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Roquer González, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Jimenez Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Soriano Tarraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Slowik, A. (Jagiellonian University Medical College, Kraków) ;
Jagiella, Jeremiasz M (Jagiellonian University Medical College, Kraków) ;
Pera, J. (Jagiellonian University Medical College, Kraków) ;
Urbanik, Andrzej (Jagiellonian University Medical College, Kraków) ;
Pichler, A. (Jagiellonian University Medical College, Kraków) ;
Hansen, Björn M (Lund University) ;
McCauley, J. L. (John P. Hussman Institute for Human Genomics, Miami) ;
Tirschwell, D. L. (University of Washington) ;
Selim, Magdy (Beth Israel Deaconess Medical Center, Boston) ;
Brown, D. L. (University of Michigan) ;
Silliman, Scott L. (University of Florida College of Medicine) ;
Worrall, B. B. (University of Virginia Health System) ;
Meschia, J. F. (Mayo Clinic, Jacksonville, Florida) ;
Kidwell, C. S. (University of Arizona) ;
Testai, F. D. (University of Illinois) ;
Kittner, S. J. (University of Maryland School of Medicine) ;
Schmidt, H. (Medical University of Graz) ;
Enzinger, C. (Medical University of Graz) ;
Deary, Ian J. (University of Edinburgh) ;
Rannikmae, K. (University of Edinburgh) ;
Samarasekera, N. (University of Edinburgh) ;
Salman, R. A. S. (University of Edinburgh) ;
Sudlow, C. L. (University of Edinburgh) ;
Klijn, C. J. M. (UMC Utrecht Brain Center Rudolf Magnus) ;
Van Nieuwenhuizen, K. M. (UMC Utrecht Brain Center Rudolf Magnus) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Norrving, B. (Lund University) ;
Lindgren, A. (Lund University) ;
Goldstein, J. N. (Massachusetts General Hospital (Boston)) ;
Viswanathan, Anand (Massachusetts General Hospital (Boston)) ;
Greenberg, S. M. (Massachusetts General Hospital (Boston)) ;
Falcone, G. J. (Yale University) ;
Biffi, Alessandro (Massachusetts General Hospital (Boston)) ;
Langefeld, Carl D (Wake Forest University, Winston-Salem, North Carolina) ;
Woo, D. (University of Cincinnati College of Medicine) ;
Rosand, J. (Massachusetts General Hospital (Boston)) ;
Anderson, C. D. (Massachusetts General Hospital (Boston)) ;
Universitat Autònoma de Barcelona
Importance: Genetic studies of intracerebral hemorrhage (ICH) have focused mainly on white participants, but genetic risk may vary or could be concealed by differing nongenetic coexposures in nonwhite populations. [...]
2019 - 10.1001/jamaneurol.2018.4519
JAMA Neurology, Vol. 76 Núm. 4 (april 2019) , p. 480-491
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11 p, 168.8 KB |
Genetic variants in CETP increase risk of intracerebral hemorrhage
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Anderson, Christopher D. (Broad Institute of MIT and Harvard) ;
Falcone, Guido J. (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ;
Phuah, Chia-Ling (Broad Institute of MIT and Harvard) ;
Radmanesh, Farid (Broad Institute of MIT and Harvard) ;
Brouwers, H. Bart (Broad Institute of MIT and Harvard) ;
Battey, Thomas W. K. (Broad Institute of MIT and Harvard) ;
Biffi, Alessandro (Division of Psychiatry, Department of Psychiatry, MGH) ;
Peloso, Gina M. (Broad Institute of MIT and Harvard) ;
Liu, Dajiang J. (Institute of Personalized Medicine, Penn State College of Medicine) ;
Ayres, Alison M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ;
Goldstein, Joshua N. (Department of Emergency Medicine, MGH) ;
Viswanathan, Anand (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ;
Greenberg, Steven M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ;
Selim, Magdy (Beth Israel Deaconess Medical Center) ;
Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ;
Brown, Devin L. (University of Michigan Health System) ;
Worrall, Bradford B. (University of Virginia Health System) ;
Silliman, Scott L. (University of Florida College of Medicine) ;
Tirschwell, David L. (University of Washington) ;
Flaherty, Matthew L. (University of Cincinnati College of Medicine) ;
Kraft, Peter (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ;
Jagiella, Jeremiasz M. (Jagiellonian University Medical College) ;
Schmidt, Helena (Medical University Graz) ;
Hansen, Björn M. (Skåne University Hospital (Suècia)) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Soriano Tàrraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ;
van Nieuwenhuizen, Koen M. (University Medical Center Utrecht) ;
Klijn, Catharina J. M. (Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center) ;
Rannikmae, Kristiina (University of Edinburgh) ;
Samarasekera, Neshika (University of Edinburgh) ;
Salman, Rustam Al-Shahi (University of Edinburgh) ;
Sudlow, Catherine L. (University of Edinburgh) ;
Deary, Ian J. (University of Edinburgh) ;
Morotti, Andrea (Neurology Clinic, University of Brescia) ;
Pezzini, Alessandro (Neurology Clinic, University of Brescia) ;
Pera, Joanna (Jagiellonian University Medical College) ;
Urbanik, Andrzej (Jagiellonian University Medical College) ;
Pichler, Alexander (Medical University of Graz) ;
Enzinger, Christian (Medical University of Graz) ;
Norrving, Bo (Skåne University Hospital (Suècia)) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Roquer González, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lindgren, Arne (Skåne University Hospital (Suècia)) ;
Slowik, Agnieszka (Jagiellonian University Medical College) ;
Schmidt, Reinhold (Medical University of Graz) ;
Kidwell, Chelsea S. (University of Arizona) ;
Kittner, Steven J. (Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine) ;
Waddy, Salina P. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ;
Langefeld, Carl D. (Wake Forest University) ;
Abecasis, Goncalo (University of Michigan School of Public Health) ;
Willer, Cristen J. (University of Michigan Medical School) ;
Kathiresan, Sekar (Cardiovascular Disease Prevention Center, MGH) ;
Woo, Daniel (University of Cincinnati College of Medicine) ;
Rosand, Jonathan (Broad Institute of MIT and Harvard) ;
Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)
In observational epidemiologic studies, higher plasma high-density lipoprotein cholesterol (HDL-C) has been associated with increased risk of intracerebral hemorrhage (ICH). DNA sequence variants that decrease cholesteryl ester transfer protein (CETP) gene activity increase plasma HDL-C; as such, medicines that inhibit CETP and raise HDL-C are in clinical development. [...]
2016 - 10.1002/ana.24780
Annals of neurology, Vol. 80 (october 2016) , p. 730-740
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