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1.
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21 p, 2.2 MB |
Self-Management Interventions for Adults Living with Type II Diabetes to Improve Patient-Important Outcomes : An Evidence Map
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Song, Yang (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Beltran, Jessica (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Medina-Aedo, Melixa (Institut d'Investigació Biomèdica Sant Pau) ;
Canelo Aybar, Carlos Gilberto (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Valli, Claudia (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ballester, Marta (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Rocha, Claudio (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
León-García, Montserrat (Institut d'Investigació Biomèdica Sant Pau) ;
Salas-Gama, Karla (Hospital Universitari Vall d'Hebron) ;
Kaloteraki, Chrysoula (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Santero, Marilina (Institut d'Investigació Biomèdica Sant Pau) ;
Niño de Guzmán, Ena Pery (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Spoiala, Cristina (Netherlands Institute for Health Services Research) ;
Gurung, Pema (Netherlands Institute for Health Services Research) ;
Willemen, Fabienne (Netherlands Institute for Health Services Research) ;
Cools, Iza (Netherlands Institute for Health Services Research) ;
Bleeker, Julia (Netherlands Institute for Health Services Research) ;
Poortvliet, Rune (Netherlands Institute for Health Services Research) ;
Laure, Tajda (Netherlands Institute for Health Services Research) ;
Van der Gaag, Marieke (Netherlands Institute for Health Services Research) ;
Pacheco-Barrios, Kevin (Avedis Donabedian Research Institute) ;
Zafra-Tanaka, Jessica (Avedis Donabedian Research Institute) ;
Mavridis, Dimitris (University of Ioannina) ;
Angeliki Veroniki, Areti (University of Toronto) ;
Zevgiti, Stella (University of Ioannina) ;
Seitidis, Georgios (University of Ioannina) ;
Alonso-Coello, Pablo (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Groene, Oliver (University of Witten/Herdecke) ;
González González, Ana Isabel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Suñol Sala, Rosa (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Orrego, Carola (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Heijmans, Monique (Netherlands Institute for Health Services Research)
Self-management interventions (SMIs) may be promising in the treatment of Diabetes Mellitus Type 2 (T2DM). However, accurate comparisons of their relative effectiveness are challenging, partly due to a lack of clarity and detail regarding the intervention content being evaluated. [...]
2023 -  10.3390/healthcare11243156
Healthcare, Vol. 11 (december 2023)
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2.
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14 p, 1.6 MB |
Effectiveness and Cost-Effectiveness of Self-Management Interventions for Adults Living with Heart Failure to Improve Patient-Important Outcomes : An Evidence Map of Randomized Controlled Trials
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Santero, Marilina (Institut de Recerca Sant Pau) ;
Song, Yang (Institut de Recerca Sant Pau) ;
Beltran, Jessica (Institut de Recerca Sant Pau) ;
Medina-Aedo, Melixa (Institut de Recerca Sant Pau) ;
Canelo Aybar, Carlos Gilberto (Institut de Recerca Sant Pau) ;
Valli, Claudia (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Rocha, Claudio (Institut de Recerca Sant Pau) ;
León-García, Montserrat (Institut de Recerca Sant Pau) ;
Salas-Gama, Karla (Hospital Universitari Vall d'Hebron) ;
Kaloteraki, Chrysoula (Institut de Recerca Sant Pau) ;
Niño de Guzmán, Ena Pery (Institut de Recerca Sant Pau) ;
Ballester, Marta (Red de Investigación en Cronicidad, Atención Primaria y Promoción de la Salud (RICAPPS)) ;
González González, Ana Isabel (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Poortvliet, Rune (Netherlands Institute for Health Services Research (NIVEL)) ;
Van der Gaag, Marieke (Netherlands Institute for Health Services Research (NIVEL)) ;
Spoiala, Cristina (Netherlands Institute for Health Services Research (NIVEL)) ;
Gurung, Pema (Netherlands Institute for Health Services Research (NIVEL)) ;
Willemen, Fabienne (Netherlands Institute for Health Services Research (NIVEL)) ;
Cools, Iza (Netherlands Institute for Health Services Research (NIVEL)) ;
Bleeker, Julia (Netherlands Institute for Health Services Research (NIVEL)) ;
Kancheva, Angelina (Netherlands Institute for Health Services Research (NIVEL)) ;
Ertl, Julia (Netherlands Institute for Health Services Research (NIVEL)) ;
Laure, Tajda (Netherlands Institute for Health Services Research (NIVEL)) ;
Kancheva, Ivana (Netherlands Institute for Health Services Research (NIVEL)) ;
Pacheco-Barrios, Kevin (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Zafra-Tanaka, Jessica (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Tsokani, Sofia (University of Ioannina) ;
Veroniki, Areti Angeliki (University of Toronto) ;
Seitidis, Georgios (University of Ioannina) ;
Christogiannis, Christos (University of Ioannina) ;
Kontouli, Katerina Maria (University of Ioannina) ;
Groene, Oliver (University of Witten/Herdecke) ;
Suñol Sala, Rosa (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Orrego, Carola (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Heijmans, Monique (Netherlands Institute for Health Services Research (NIVEL)) ;
Alonso-Coello, Pablo (Institut de Recerca Sant Pau)
Self-management interventions (SMIs) may enhance heart failure (HF) outcomes and address challenges associated with disease management. This study aims to review randomized evidence and identify knowledge gaps in SMIs for adult HF patients. [...]
2024 - 10.3390/healthcare12030302
Healthcare, Vol. 12 (january 2024)
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3.
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19 p, 294.4 KB |
COMPAR-EU Recommendations on Self-Management Interventions in Type 2 Diabetes Mellitus
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Beltran, Jessica (Institut de Recerca Sant Pau) ;
Valli, Claudia (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Medina-Aedo, Melixa (Institut de Recerca Sant Pau) ;
Canelo Aybar, Carlos Gilberto (Institut de Recerca Sant Pau) ;
Niño de Guzmán, Ena Pery (Institut de Recerca Sant Pau) ;
Song, Yang (Institut de Recerca Sant Pau) ;
Orrego, Carola (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Ballester, Marta (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Suñol Sala, Rosa (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Noordman, Janneke (Netherlands Institute for Health Services Research (NIVEL)) ;
Heijmans, Monique (Netherlands Institute for Health Services Research (NIVEL)) ;
Seitidis, Georgios (University of Ioannina) ;
Tsokani, Sofia (University of Ioannina) ;
Kontouli, Katerina Maria (University of Ioannina) ;
Christogiannis, Christos (University of Ioannina) ;
Mavridis, Dimitris (University of Ioannina) ;
de Graaf, Gimon (Erasmus University Rotterdam) ;
Groene, Oliver (OptiMedis) ;
Grammatikopoulou, Maria G. (University of Thessaly) ;
Camalleres-Guillem, Francisco (Centro de Salud Infanta Mercedes) ;
Perestelo-Pérez, Lilisbeth (Servicio Canario de la Salud) ;
McGloin, Helen (ATU St Angelas) ;
Winkley, Kirsty (King's College London) ;
Mueller, Beate Sigrid (University of Cologne) ;
Saz-Parkinson, Zuleika (European Research Executive Agency) ;
Corcoy i Pla, Rosa (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Alonso-Coello, Pablo (Institut de Recerca Sant Pau)
Self-management interventions (SMIs) offer a promising approach to actively engage patients in the management of their chronic diseases. Within the scope of the COMPAR-EU project, our goal is to provide evidence-based recommendations for the utilisation and implementation of SMIs in the care of adult individuals with type 2 diabetes mellitus (T2DM). [...]
2024 - 10.3390/healthcare12040483
Healthcare, Vol. 12 (february 2024)
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4.
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7 p, 998.5 KB |
Assessing the electrochemical CO2 reduction reaction performance requires more than reporting coulombic efficiency
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Izadi, Paniz (Helmholtz Centre for Environmental Research (Leipzig, Alemanya)) ;
Song,Jia (Vlaamse Instelling voor Technologisch Onderzoek) ;
Singh,Chandani (Vlaamse Instelling voor Technologisch Onderzoek) ;
Pant, Deepak (Vlaamse Instelling voor Technologisch Onderzoek) ;
Harnisch, Falk (Helmholtz Centre for Environmental Research (Leipzig, Alemanya))
Reporting coulombic efficiency (CE) is the common way to assess the performance of electrochemical carbon dioxide (CO2) reduction reaction (eCO2RR) in literature, whereas its carbon conversion efficiency (CCE) is frequently neglected. [...]
2024 - 10.1002/aesr.202400031
Advanced Energy & Sustainability research, (February 2024) , art. 2400031
2 documentos
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5.
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8 p, 313.2 KB |
Delphi survey of intercontinental experts to identify areas of consensus on the use of indocyanine green angiography for tissue perfusion assessment during plastic and reconstructive surgery
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Schols, Rutger M. (Maastricht University Medical Center) ;
Dip, Fernando (Hospital de Clínicas José de San Martín) ;
Lo Menzo, Emanuele (Cleveland Clinic Florida) ;
Haddock, Nicholas T. (University of Texas Southwestern Medical Center) ;
Landin, Luis (Hospital Universitario La Paz (Madrid)) ;
Lee, Bernard T. (Harvard Medical School) ;
Malagón, Paloma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Masià, Jaume (Institut d'Investigació Biomèdica Sant Pau) ;
Mathes, David W. (University of Colorado) ;
Nahabedian, Maurice Y. (Center for Plastic Surgery) ;
Neligan, Peter C. (University of Washington) ;
Newman, Martin I. (Cleveland Clinic Florida) ;
Phillips, Brett T. (Duke University Hospital) ;
Pons, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Pruimboom, Tim (Maastricht University Medical Center) ;
Qiu, Shan Shan (Maastricht University Medical Center) ;
Ritschl, Lucas M. (Klinikum rechts der Isar) ;
Rozen, Warren M. (Monash University. Peninsula Campus) ;
Saint-Cyr, Michael (MD Anderson Cancer Center) ;
Song, Seung Yong (Yonsei University College of Medicine) ;
van der Hulst, René R.W.J. (Maastricht University Medical Center) ;
Venturi, Mark L. (VCU School of Medicine INOVA) ;
Wongkietkachorn, Apinut (Mae Fah Luang University) ;
Yamamoto, Takumi (National Center for Global Health and Medicine) ;
White, K.P. (ScienceRight Research Consulting Services) ;
Rosenthal, Raul J. (Cleveland Clinic Florida) ;
Universitat Autònoma de Barcelona
In recent years, indocyanine green angiography (ICG-A) has been used increasingly to assist tissue perfusion assessments during plastic and reconstructive surgery procedures, but no guidelines exist regarding its use. [...]
2022 - 10.1016/j.surg.2022.04.015
Surgery (United States), Vol. 172 Núm. 6 (december 2022) , p. S46-S53
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6.
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13 p, 1.7 MB |
Consensus goals and standards for specialist cough clinics : the NEUROCOUGH international Delphi study
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Song, Woo-Jung (University of Ulsan College of Medicine) ;
Dupont, Lieven (University Hospitals Leuven (Bèlgica)) ;
Birring, Surinder S. (King's College London) ;
Chung, Kian Fan (Imperial College London) ;
Dąbrowska, Marta (Medical University of Warsaw) ;
Dicpinigaitis, Peter (Albert Einstein College of Medicine and Montefiore Medical Center) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fontana, Giovanni (University of Florence) ;
Gibson, Peter G. (University of Newcastle) ;
Guilleminault, Laurent (Hôpital Larrey and Center for Pathophysiology Toulouse Purpan) ;
Hull, James H. (Royal Brompton Hospital (Londres)) ;
Idzko, Marco (Medical University of Vienna) ;
Kardos, Peter (Maingau Clinic of the Red Cross) ;
Kim, Hyun Jung (Korea University College of Medicine) ;
Lai, Kefang (Guangzhou Institute of Respiratory Health) ;
Lavorini, Federico (University of Florence) ;
Millqvist, Eva (University of Gothenburg) ;
Morice, Alyn H. (University of Hull) ;
Niimi, Akio (Nagoya City University) ;
Parker, Sean M. (North Tyneside General Hospital) ;
Satia, Imran (McMaster University (Canadà)) ;
Smith, Jaclyn A. (University of Manchester) ;
van den Berg, Jan Willem (Isala Hospital) ;
McGarvey, Lorcan P. (Queen's University Belfast) ;
Universitat Autònoma de Barcelona
Current guidelines on the management of chronic cough do not provide recommendations for the operation of specialist cough clinics. The objective of the present study was to develop expert consensus on goals and standard procedures for specialist cough clinics. [...]
2023 - 10.1183/23120541.00618-2023
ERJ Open Research, Vol. 9 (november 2023)
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7.
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15 p, 1.6 MB |
A trans-omics assessment of gene-gene interaction in early-stage NSCLC
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Chen, Jiajin (Nanjing Medical University) ;
Song, Yunjie (Department of Biostatistics. Nanjing Medical University) ;
Li, Yi (Department of Biostatistics. University of Michigan) ;
Wei, Yongyue (Nanjing Medical University) ;
Shen, Sipeng (Department of Biostatistics. Nanjing Medical University) ;
Zhao, Yang (Department of Biostatistics. Nanjing Medical University) ;
You, Dongfang (Department of Biostatistics. Nanjing Medical University) ;
Su, Li (Harvard Medical School) ;
Bjaanæs, Maria Moksnes (Department of Cancer Genetics Oslo University Hospital) ;
Karlsson, Anna (Department of Clinical Sciences. Lund University) ;
Planck, Maria (Department of Clinical Sciences. Lund University) ;
Staaf, Johan (Department of Clinical Sciences. Lund University) ;
Helland, Åslaug (Institute of Clinical Medicine. University of Oslo) ;
Esteller, M (Universitat de Barcelona) ;
Shen, Hongbing (Nanjing Medical University) ;
Christiani, David C. (Harvard Medical School) ;
Zhang, Ruyang (Nanjing Medical University) ;
Chen, Feng (State Key Laboratory of Reproductive Medicine. Nanjing Medical University)
Epigenome-wide gene-gene (G × G) interactions associated with non-small-cell lung cancer (NSCLC) survival may provide insights into molecular mechanisms and therapeutic targets. Hence, we proposed a three-step analytic strategy to identify significant and robust G × G interactions that are relevant to NSCLC survival. [...]
2023 - 10.1002/1878-0261.13345
Molecular Oncology, Vol. 17 Núm. 1 (january 2023) , p. 173-187
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8.
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37 p, 20.5 MB |
Epigenetic regulation during cancer transitions across 11 tumour types
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Terekhanova, Nadezhda V. (Washington University in St Louis) ;
Karpova, Alla (Washington University in St Louis) ;
Liang, Wen Wei (Washington University in St Louis) ;
Strzalkowski, Alexander (Department of Computer Science. Princeton University) ;
Chen, Siqi (Washington University in St Louis) ;
Li, Yize (Washington University in St Louis) ;
Southard-Smith, Austin N. (Washington University in St Louis) ;
Iglesia, Michael D. (Washington University in St Louis) ;
Wendl, Michael C. (Washington University in St Louis) ;
Jayasinghe, Reyka G. (Washington University in St Louis) ;
Liu, Jingxian (Washington University in St Louis) ;
Song, Yizhe (Washington University in St Louis) ;
Cao, Song (Washington University in St Louis) ;
Houston, Andrew (Washington University in St Louis) ;
Liu, Xiuting (Department of Medicine. Washington University in St Louis) ;
Wyczalkowski, Michael A. (Washington University in St Louis) ;
Lu, Rita Jui-Hsien (Washington University in St Louis) ;
Caravan, Wagma (Washington University in St Louis) ;
Shinkle, Andrew (Department of Medicine. Washington University in St Louis) ;
Naser Al Deen, Nataly (Washington University in St Louis) ;
Herndon, John M. (Washington University in St Louis) ;
Mudd, Jacqueline (Department of Surgery. Washington University in St Louis) ;
Ma, Cong (Department of Computer Science. Princeton University) ;
Sarkar, Hirak (Department of Computer Science. Princeton University) ;
Sato, Kazuhito (Washington University in St Louis) ;
Ibrahim, Omar.M. (Washington University in St Louis) ;
Mo, Chia-Kuei (Washington University in St Louis) ;
Chasnoff, Sara E. (Washington University in St Louis) ;
Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Held, Jasson M. (Washington University in St Louis) ;
Pachynski, Russell (Washington University in St Louis) ;
Schwarz, Julie K. (Department of Radiation Oncology. Washington University in St Louis) ;
Gillanders, William E. (Washington University in St Louis) ;
Kim, Albert H. (Department of Neurological Surgery. Washington University in St Louis) ;
Vij, Ravi (Washington University in St Louis) ;
DiPersio, John.F. (Washington University in St Louis) ;
Puram, Sidharth V. (Department of Otolaryngology-Head & Neck Surgery. Washington University in St Louis) ;
Chheda, Milan G. (Washington University in St Louis) ;
Fuh, Katherine C. (Department of Obstetrics and Gynecology. Washington University in St Louis) ;
DeNardo, David G. (Washington University in St Louis) ;
Fields, Ryan C. (Washington University in St Louis) ;
Chen, Feng (Washington University in St Louis) ;
Raphael, Benjamin J. (Department of Computer Science. Princeton University) ;
Ding, Li (Department of Genetics. Washington University in St Louis)
Chromatin accessibility is essential in regulating gene expression and cellular identity, and alterations in accessibility have been implicated in driving cancer initiation, progression and metastasis. [...]
2023 - 10.1038/s41586-023-06682-5
Nature, Vol. 623 Núm. 7986 (september 2023) , p. 432-441
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9.
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50 p, 28.5 MB |
Pan-cancer proteogenomics connects oncogenic drivers to functional states
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Li, Yize (Washington University in St. Louis) ;
Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Tokheim, Collin (Harvard T.H. Chan School of Public Health) ;
Bailey, Matthew H. (Brigham Young University) ;
Yaron, Tomer (Weill Cornell Medicine) ;
Stathias, Vasileios (University of Miami Miller School of Medicine) ;
Geffen, Yifat (Massachusetts General Hospital) ;
Imbach, Kathleen (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Cao, Song (McDonnell Genome Institute) ;
Anand, Shankara (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Akiyama, Yo (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Liu, Wenke (NYU Grossman School of Medicine) ;
Wyczalkowski, Matthew A. (McDonnell Genome Institute) ;
Song, Yizhe (McDonnell Genome Institute) ;
Storrs, Erik P. (McDonnell Genome Institute) ;
Wendl, Michael C. (Washington University in St. Louis) ;
Zhang, Wubing (Dana-Farber Cancer Institute (Boston, Estats Units)) ;
Sibai, Mustafa (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ruiz-Serra, Victoria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Liang, Wen-Wei (McDonnell Genome Institute) ;
Terekhanova, Nadezhda V. (McDonnell Genome Institute) ;
Martins Rodrigues, Fernanda (McDonnell Genome Institute) ;
Clauser, Karl R. (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Heiman, David I. (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Zhang, Qing (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Aguet, Francois (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Calinawan, Anna Pamela (Icahn School of Medicine at Mount Sinai) ;
Dhanasekaran, Saravana Mohan (University of Michigan) ;
Birger, Chet (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Satpathy, Shankha (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Zhou, Daniel Cui (McDonnell Genome Institute) ;
Wang, Liang-Bo (McDonnell Genome Institute) ;
Baral, Jessika (McDonnell Genome Institute) ;
Johnson, Jared L. (Weill Cornell Medicine) ;
Huntsman, Emily M. (Weill Cornell Medicine) ;
Pugliese, Pietro (University of Sannio (Benevento, Itàlia)) ;
Colaprico, Antonio (University of Miami Miller School of Medicine) ;
Iavarone, Antonio (University of Miami Miller School of Medicine) ;
Chheda, Milan G. (Washington University in St. Louis) ;
Ricketts, Christopher J. (National Institutes of Health) ;
Fenyö, David (NYU Grossman School of Medicine) ;
Payne, Samuel H. (Brigham Young University) ;
Rodriguez, Henry (Office of Cancer Clinical Proteomics Research) ;
Robles, Ana I. (Office of Cancer Clinical Proteomics Research) ;
Gillette, Michael A. (Harvard Medical School) ;
Kumar-Sinha, Chandan (University of Michigan) ;
Lazar, Alexander (The University of Texas MD Anderson Cancer Center) ;
Cantley, Lewis (Weill Cornell Medicine) ;
Getz, Gad A. (Harvard Medical School) ;
Ding, Li (Siteman Cancer Center) ;
An, Eunkyung ;
Anurag, Meenakshi ;
Bavarva, Jasmin ;
Birrer, Michael J. ;
Ceccarelli, Michele ;
Chan, Daniel W. ;
Chinnaiyan, Arul M. ;
Cho, Hanbyul ;
Chowdhury, Shrabanti ;
Cieslik, Marcin P. ;
da Veiga Leprevost, Felipe ;
Day, Corbin ;
Domagalski, Marcin J. ;
Dou, Yongchao ;
Druker, Brian J. ;
Edwards, Nathan ;
Ellis, Matthew J. ;
Selvan, Myvizhi Esai ;
Foltz, Steven M. ;
Francis, Alicia ;
Gonzalez Robles, Tania J. ;
Gosline, Sara J. C. ;
Gümüş, Zeynep H. ;
Hiltke, Tara ;
Hong, Runyu ;
Hostetter, Galen ;
Hu, Yingwei ;
Huang, Chen ;
Huntsman, Emily ;
Jaehnig, Eric J. ;
Jewel, Scott D. ;
Ji, Jiayi ;
Jiang, Wen ;
Katsnelson, Lizabeth ;
Ketchum, Karen A. ;
Kolodziejczak, Iga ;
Lei, Jonathan T. ;
Liao, Yuxing ;
Lindgren, Caleb M. ;
Liu, Tao ;
Ma, Weiping ;
McKerrow, Wilson ;
Nesvizhskii, Alexey I. ;
Newton, Chelsea ;
Oldroyd, Robert ;
Omenn, Gilbert S. ;
Paulovich, Amanda G. ;
Petralia, Francesca ;
Reva, Boris ;
Rodland, Karin D. ;
Ruggles, Kelly V. ;
Rykunov, Dmitry ;
Savage, Sara R. ;
Schadt, Eric E. ;
Schnaubelt, Michael ;
Schraink, Tobias ;
Shi, Zhiao ;
Smith, Richard D. ;
Song, Xiaoyu ;
Tan, Jimin ;
Thangudu, Ratna R. ;
Tignor, Nicole ;
Wang, Joshua M. ;
Wang, Pei ;
Wang, Ying Cindy ;
Wen, Bo ;
Wiznerowicz, Maciej ;
Yi, Xinpei ;
Zhang, Bing ;
Zhang, Hui ;
Zhang, Xu ;
Zhang, Zhen ;
Universitat Autònoma de Barcelona
Cancer driver events refer to key genetic aberrations that drive oncogenesis; however, their exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan-cancer analysis uncovers insights into the impacts of cancer drivers by identifying their significant cis-effects and distal trans-effects quantified at the RNA, protein, and phosphoprotein levels. [...]
2023 - 10.1016/j.cell.2023.07.014
Cell, Vol. 186 Núm. 18 (31 2023) , p. 3921-3944.e25
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10.
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27 p, 8.1 MB |
Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin
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Liang, Wen-Wei (Washington University in St. Louis) ;
Lu, Rita Jui-Hsien Lu (Washington University in St. Louis) ;
Jayasinghe, Reyka G. (Washington University in St. Louis) ;
Foltz, Steven M. (Washington University in St. Louis) ;
Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Geffen, Yifat (Massachusetts General Hospital) ;
Wendl, Michael C. (Department of Mathematics. Washington University in St. Louis) ;
Lazcano, Rossana (Departments of Pathology & Genomic Medicine. The University of Texas MD Anderson Cancer Center) ;
Kolodziejczak, Iga (Medical University of Warsaw) ;
Song, Yizhe (Washington University in St. Louis) ;
Govindan, Akshay (Washington University in St. Louis) ;
Demicco, Elisabeth G. (University of Toronto) ;
Li, Xiang (Washington University in St. Louis) ;
Li, Yize (Washington University in St. Louis) ;
Sethuraman, Sunantha (Washington University in St. Louis) ;
Payne, Samuel H. (Department of Biology. Brigham Young University) ;
Fenyö, David (Department of Biochemistry and Molecular Pharmacology. NYU Grossman School of Medicine) ;
Rodriguez, Henry (Office of Cancer Clinical Proteomics Research. National Cancer Institute) ;
Wiznerowicz, Maciej (Poznań University of Medical Sciences) ;
Shen, Hui (Van Andel Research Institute) ;
Mani, D.R. (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Rodland, Karin D. (Developmental. and Cancer Biology. Oregon Health & Science University) ;
Lazar, Alexander J. (Departments of Pathology & Genomic Medicine. The University of Texas MD Anderson Cancer Center) ;
Robles, Ana I. (Office of Cancer Clinical Proteomics Research) ;
Ding, Li (Washington University in St. Louis) ;
Universitat Autònoma de Barcelona
DNA methylation plays a critical role in establishing and maintaining cellular identity. However, it is frequently dysregulated during tumor development and is closely intertwined with other genetic alterations. [...]
2023 - 10.1016/j.ccell.2023.07.013
Cancer Cell, Vol. 41 Núm. 9 (november 2023) , p. 1567-1585.e7
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