Diversity of pyrrolizidine alkaloids in native and invasive Senecio pterophorus (Asteraceae) : Implications for toxicity
Castells, Eva (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Mulder, Patrick P. J.
Pérez-Trujillo, Míriam (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear)

Data:	2014
Resum:	Changes in plant chemical defenses after invasion could have consequences on the invaded ecosystems by modifying the interactions between plants and herbivores and facilitating invasion success. However, no comprehensive biogeographical studies have yet determined the phenotypic levels of plant chemical defenses, as consumed by local herbivores, covering large distributional areas of a species. Senecio ptero-phorus is a perennial shrub native to Eastern South Africa, expanded into Western South Africa and introduced into Australia and Europe. As other Asteraceae, S. pterophorus contains pyrrolizidine alkaloids (PAs) toxic to vertebrate and invertebrate herbivores. Here we analyzed S. pterophorus PAs by LC-MS/MS on foliage sampled across its entire distributional range, including the native and all non-native areas. PA concentrations and diversity was very high: we found 57 compounds belonging to 6 distinct necine base-types, including the highly toxic 1,2-unsaturated PAs (retronecine and otonecines) and the less toxic 1,2-saturated PAs (platynecine and rosmarinecines). Plants from different origins diverged in their PA absolute and relative concentrations. Rosmarinine was the most abundant compound in Australia and South Africa, but it was nearly absent in Europe. We characterized three plant chemotypes: retrorsine-senkirkine chemotype in Eastern South Africa, rosmarinine chemotype in Australia and Western South Africa, and acetylseneciphylline chemotype in Europe. PA absolute concentrations were highest in Australia. The increased absolute and relative concentrations of retronecine PAs from Australia and Europe, respectively, indicate that S. pterophorus is potentially more toxic in the invasive range than in the native range.
Ajuts:	Ministerio de Ciencia e Innovación GCL2008-02421/BOS Ministerio de Ciencia e Innovación GCL2011-29205 Agència de Gestió d'Ajuts Universitaris i de Recerca 2009/SGR-1058
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Llengua:	Català
Document:	Article ; recerca ; Versió publicada
Matèria:	Senecio pterophorus ; Asteraceae ; Geographical diversity ; Pyrrolizidine alkaloids ; Chemotypes ; Invasive species ; Toxicity ; LC-MS/MSParaules clau fora catàleg
Publicat a:	Phytochemistry, Vol. 108 (Dec 2014) , p. 137-146, ISSN 0031-9422
Obra relacionada:	Castells Caballe, Eva, 2014. Pyrrolizidine alkaloids in Senecio pterophorus from the native and invasive range, CORA.Repositori de Dades de Recerca, V1 https://doi.org/10.34810/data1397

DOI: 10.1016/j.phytochem.2014.09.006

36 p, 229.4 KB

10 p, 493.6 KB

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