Severity Stages in Essential Tremor : A Long-Term Retrospective Study Using the Glass Scale
Gironell, Alexandre (Institut d'Investigació Biomèdica Sant Pau)
Ribosa-Nogué, Roser (Institut d'Investigació Biomèdica Sant Pau)
Gich, Ignasi (Institut d'Investigació Biomèdica Sant Pau)
Marin-Lahoz, Juan (Institut d'Investigació Biomèdica Sant Pau)
Pascual-Sedano, Berta María (Institut d'Investigació Biomèdica Sant Pau)
Universitat Autònoma de Barcelona. Departament de Medicina

Date:	2015
Abstract:	Few prospective studies have attempted to estimate the rate of decline of essential tremor (ET) and these were over a relatively short time period (less than 10 years). We performed a long-term study of severity stages in ET using the Glass Scale scoring system. Fifty consecutive patients with severe ET were included. We retrospectively obtained Glass Scale scores throughout the patient's life. Common milestone events were used to help recall changes in tremor severity. According to the Glass Scale, the age distributions were as follows: score I, 40±17 years, score II, 55±12 years, score III, 64±9 years, and score IV, 69±7 years. A significant negative correlation between age at first symptom and rate of progression was found (r = -0. 669, p 0. 001). The rate of progression was significantly different (p 0. 001) when the first symptom appeared at a younger age (under 40 years of age) compared with older age (40 years or older). Our results support the progressive nature of ET. Age at onset was a prognostic factor. The Glass Scale may be a useful tool to determine severity stages during the course of ET in a manner similar to the Hoehn and Yahr Scale for Parkinson's disease.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Essential tremor ; Glass Scale ; Essential tremor progression
Published in:	Tremor and Other Hyperkinetic Movements, Vol. 5 (march 2015) , ISSN 2160-8288

DOI: 10.7916/D8DV1HQC
PMID: 25793146

5 p, 916.8 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
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