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Pàgina inicial > Articles > Articles publicats > Shared and differential default-mode related patterns of activity in an autobiographical, a self-referential and an attentional task |
Data: | 2019 |
Resum: | The default-mode network (DMN) comprises a set of brain regions that show deactivations during performance of attentionally demanding tasks, but also activation during certain processes including recall of autobiographical memories and processing information about oneself, among others. However, the DMN is not activated in a homogeneous manner during performance of such tasks, so it is not clear to what extent its activation patterns correspond to deactivation patterns seen during attention-demanding tasks. In this fMRI study we compared patterns of activation in response to an autobiographical memory task to those observed in a self/other-reflection task, and compared both to deactivations observed during the n-back working memory task. Autobiographical recall and self-reflection activated several common DMN areas, which were also deactivated below baseline levels by the n-back task. Activation in the medial temporal lobe was seen during autobiographical recall but not the self/other task, and right angular gyrus activity was specifically linked to other-reflection. ROI analysis showed that most, but not all DMN regions were activated above baseline levels during the autobiographical memory and self-reflection tasks. Our results provide evidence for the usefulness of the autobiographical memory task to study DMN activity and support the notion of interacting subsystems within this network. |
Ajuts: | Agència de Gestió d'Ajuts Universitaris i de Recerca 2014-SGR-1573 Instituto de Salud Carlos III CPII13-00018 Instituto de Salud Carlos III MS10-00596 Instituto de Salud Carlos III CM15-00024 Instituto de Salud Carlos III FI16-00311 Instituto de Salud Carlos III PI14-01151 Instituto de Salud Carlos III PI14-01148 Instituto de Salud Carlos III PI14-01691 |
Drets: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. |
Llengua: | Anglès |
Document: | Article ; recerca ; Versió publicada |
Matèria: | Adolescent ; Adult ; Aged ; Attention ; Brain ; Brain Mapping ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Memory, Episodic ; Memory, Short-Term ; Mental Recall ; Middle Aged ; Nerve Net ; Neural Pathways ; Self-Assessment ; Task Performance and Analysis ; Young Adult |
Publicat a: | PloS one, Vol. 14 (january 2019) , ISSN 1932-6203 |
21 p, 1.8 MB |