Phytogenic Compounds Supplemented to Gestating Hyperprolific Sows Affects the Gut Health-Related Gene Expression and Histological Responses in Neonate Piglets
Reyes-Camacho, David (Universitat Autònoma de Barcelona. Servei de Nutrició i Benestar Animal)
Pérez Hernández, José Francisco (Universitat Autònoma de Barcelona)
Vinyeta, Ester (Delacon Biotechnik)
Aumiller, Tobias (Delacon Biotechnik)
Criado Mesas, Lourdes (Centre de Recerca en Agrigenòmica)
Folch, Josep M (Centre de Recerca en Agrigenòmica)
Van der Klis, Jan Dirk (Delacon Biotechnik)
Solà Oriol, David (Universitat Autònoma de Barcelona)
Universitat Autònoma de Barcelona. SGR-Grup de Recerca de Nutrició Maneig i Benestar Animal

Date:	2021
Abstract:	This research aims to determine whether a specific blend of phytogenic compounds (BPC) supplemented in gestating hyperprolific sow diets can promote prenatal maternal effects in terms of piglet gut function and morphology. Twenty-eight (Landrace × Yorkshire) gilts and sows (parity 0 to 7) were randomly distributed by parity number and body weight into two dietary treatments: unsupplemented Control (CON) (n = 14) or CON diet supplemented with 1 g/kg feed of BPC during gestation (n = 14). The BPC supplementation during gestation of sows downregulated the neonate piglets' jejunal genes involved in oxidation (SOD2) and nutrient transport (SLC16A1/MCT1, SLC11A2/DMT1, and SLC39A/ZIP4), while IFNG and CLDN4 related to immune response and barrier function, respectively, were upregulated (q < 0. 10). In addition, the jejunal villus height and the ratio of the villus height to crypt depth tended to increase (p < 0. 10), while goblet cell volume density was higher (p < 0. 05) in BPC compared to CON. In conclusion, dietary supplementation of BPC in gestating diets for hyperprolific sows influences neonatal histomorphology and expression of genes related to the intestinal function and health.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Hyperprolific sows ; Prenatal exposure ; Neonatal programming ; Phytogenic compounds ; Piglet gut health
Published in:	Frontiers in veterinary science, Vol. 8 (june 2021) , ISSN 2297-1769

Adreça alternativa: https://publons.com/publon/48276352/
DOI: 10.3389/fvets.2021.639719
PMID: 34195241

7 p, 201.6 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles