Plasma-Ionized Magnesium in Hospitalized Horses with Gastrointestinal Disorders and Systemic Inflammatory Response Syndrome
Sanmartí, Julia ![ORCID Identifier](/img/uab/orcid.ico)
(Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Armengou Ruiz, Lara ![ORCID Identifier](/img/uab/orcid.ico)
(Universitat Autònoma de Barcelona. Fundació Hospital Clínic Veterinari)
Troya-Portillo, Lucas ![ORCID Identifier](/img/uab/orcid.ico)
(Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Robles-Guirado, José-Ángel ![ORCID Identifier](/img/uab/orcid.ico)
(Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Bassols Teixidó, Anna Maria ![ORCID Identifier](/img/uab/orcid.ico)
(Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Ríos, José ![ORCID Identifier](/img/uab/orcid.ico)
(Universitat Autònoma de Barcelona. Departament de Medicina)
José Cunilleras, Eduard
(Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Date: |
2022 |
Abstract: |
Magnesium disorders in horses with gastrointestinal disorders or systemic inflammatory response syndrome (SIRS) are scarcely characterized. The purpose of the study was to explore the association of magnesium disorders with diagnosis, SIRS and mortality in horses admitted to a referral equine hospital. In total, 75 sick horses were included in an observational prospective study and classified as: obstructive (n = 17), inflammatory (n = 10) and ischemic gastrointestinal disorders (n = 12), and other non-gastrointestinal systemic disorders (n = 36). All sick horses were also divided according to the presence (n = 26) or absence of SIRS, and survival to discharge from hospital (survivors (n = 61) and non-survivors (n = 14). In addition, 26 horses were included as controls. On admission, mean (iMg) (95% confidence interval (CI)) in the SIRS group (0. 47 (0. 43-0. 50 mmol/L)) was within the normal range (0. 4-0. 6 mmol/L). The obstructive group had lower (iMg) compared to the control group (0. 44 (0. 38-0. 51 mmol/L) vs. 0. 56 (0. 50-0. 61 mmol/L); p = 0. 001). In total, 8 out of 17 (47%) horses with obstructive lesions presented with hypomagnesemia compared to controls (4% (1/26)) (p = 0. 001). In conclusion, hypomagnesemia was more prevalent on admission in horses in the obstructive group, and to a lesser extent, in the inflammatory and ischemic groups. In contrast to human ICU patients, the proportion of hospitalized horses with hypomagnesemia was not associated with mortality. |
Note: |
Altres ajuts: Nova Biomedical Corporation |
Rights: |
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Language: |
Anglès |
Document: |
Article ; recerca ; Versió publicada |
Subject: |
Hypomagnesemia ;
Hypocalcemia ;
Gastrointestinal disorders ;
Electrolytes ;
Equine |
Published in: |
Animals, Vol. 12 Núm. 12 (6-2 2022) , p. 1479, ISSN 2076-2615 |
DOI: 10.3390/ani12121479
PMID: 35739816
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Record created 2022-06-22, last modified 2023-04-19