Lifestyle trajectories in middle-aged adults and their relationship with health indicators
Roca-Ventura, Alba (Institut Germans Trias i Pujol. Institut Guttmann)
Solana-Sánchez, Javier (Universitat Autònoma de Barcelona. Departament de Medicina)
Cattaneo, Gabriele (Universitat Autònoma de Barcelona. Departament de Medicina)
Tormos-Muñoz, Josep M. (Institut Germans Trias i Pujol)
Pascual Leone, Álvaro (Harvard Medical School)
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann)

Date:	2024
Abstract:	Understanding the impact of different lifestyle trajectories on health preservation and disease risk is crucial for effective interventions. This study analyzed lifestyle engagement over five years in 3,013 healthy adults aged 40-70 from the Barcelona Brain Health Initiative using K-means clustering. Nine modifiable risk factors were considered, including cognitive, physical, and social activity, vital plan, diet, obesity, smoking, alcohol consumption, and sleep. Self-reported diagnoses of new diseases at different time-points after baseline allowed to explore the association between these five profiles and health outcomes. The data-driven analysis classified subjects into five lifestyle profiles, revealing associations with health behaviors and risk factors. Those exhibiting high scores in health-promoting behaviors and low-risk behaviors, demonstrate a reduced likelihood of developing diseases (p < 0. 001). In contrast, profiles with risky habits showed distinct risks for psychiatric, neurological, and cardiovascular diseases. Participant's lifestyle trajectories remained relatively stable over time. Our findings have identified risk for distinct diseases associated to specific lifestyle patterns. These results could help in the personalization of interventions based on data-driven observation of behavioral patterns and policies that promote a healthy lifestyle and can lead to better health outcomes for people in an aging society.
Grants:	"la Caixa" Foundation LCF/PR/PR16/11110004 Ministerio de Ciencia e Innovación PID2022-137234OB-100 Agencia Estatal de Investigación PID-2022-139298OA-C22
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Health ; Lifestyles ; Clustering ; Joint trajectories ; K-means ; Multiple health behaviors ; Ageing ; Brain health
Published in:	Frontiers in Public Health, Vol. 12 (june 2024) , ISSN 2296-2565

DOI: 10.3389/fpubh.2024.1412547
PMID: 38903574

9 p, 2.4 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles