Is exposure to pollen a risk factor for moderate and severe asthma exacerbations?
Annesi-Maesano, Isabella (University Hospital of Montpellier (França))
Cecchi, Lorenzo (USL Toscana Centro)
Biagioni, Benedetta (San Giovanni di Dio Hospital)
Chung, Kian Fan (Imperial College London)
Clot, Bernard (Federal Office of Meteorology and Climatology MeteoSwiss)
Collaud Coen, Martine (Federal Office of Meteorology and Climatology MeteoSwiss)
D'Amato, Gennaro (Hospital Cardarelli)
Damialis, Athanasios (Aristotle University of Thessaloniki)
Dominguez-Ortega, Javier (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
Galàn, Carmen (University of Cordoba)
Gilles-Stein, Stefanie (University of Augsburg)
Holgate, Stephen (University of Southampton)
Jeebhay, Mohamed (University of Cape Town)
Kazadzis, Stelios (Physikalisch-Meteorologisches Observatorium Davos)
Papadopoulos, Nikolaos G. (University of Manchester)
Quirce, Santiago (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
Sastre, Joaquin (Instituto de Salud Carlos III)
Tummon, Fiona (Federal Office of Meteorology and Climatology MeteoSwiss)
Traidl-Hoffmann, Claudia (Christine Kühne Center for Allergy Research and Education)
Walusiak-Skorupa, Jolanta (Nofer Institute of Occupational Medicine)
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau)
Canelo Aybar, Carlos Gilberto (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Cantero-Fortiz, Yahveth (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Rigau, David (Institut d'Investigació Biomèdica Sant Pau)
Salazar, Juliana (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Verdugo-Paiva, Francisca (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Jutel, Marek (Wrocław Medical University)
Akdis, Cezmi A (University Zurich)
Agache, Ioana (Transylvania University)
Universitat Autònoma de Barcelona

Data:	2023
Resum:	Limited number of studies have focused on the impact of pollen exposure on asthma. As a part of the EAACI Guidelines on Environment Science, this first systematic review on the relationship of pollen exposure to asthma exacerbations aimed to bridge this knowledge gap in view of implementing recommendations of prevention. We searched electronic iPubMed, Embase, and Web of Science databases using a set of MeSH terms and related synonyms and identified 73 eligible studies that were included for systemic review. When possible, meta-analyses were conducted. Overall meta-analysis suggests that outdoor pollen exposure may have an effect on asthma exacerbation, but caution is needed due to the low number of studies and their heterogeneity. The strongest associations were found between asthma attacks, asthma-related ED admissions or hospitalizations, and an increase in grass pollen concentration in the previous 2-day overall in children aged less than 18 years of age. Tree pollen may increase asthma-related ED visits or admissions lagged up to 7-day overall in individuals younger than 18 years. Rare data show that among subjects under 18 years of age, an exposure to grass pollen lagged up to 3 days may lower lung function. Further research considering effect modifiers of pollen sensitization, hay fever, asthma, air pollution, green spaces, and pre-existing medications is urgently warranted to better evaluate the impacts of pollen on asthma exacerbation. Preventive measures in relation to pollen exposure should be integrated in asthma control as pollen increase continues due to climate change.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Matèria:	Aerobiology ; Asthma ; Pollen
Publicat a:	Allergy, Vol. 78 Núm. 8 (august 2023) , p. 2121-2147, ISSN 1398-9995

DOI: 10.1111/all.15724
PMID: 36961370

27 p, 1.7 MB

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