Longitudinal study for the early detection of autism in children with very preterm birth
Marín Soro, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències)
Gisbert-Gustemps, Laura (Hospital Universitari Vall d'Hebron)
Boix, Hector (Hospital Quirón (Barcelona, Catalunya))
Martínez-Maldonado, Sergi (Universitat Oberta de Catalunya)
Coronado Contreras, Ricard (Hospital General de Granollers)
Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal

Date:	2024
Abstract:	Introduction: Very preterm birth is an important risk factor for autism spectrum disorder (ASD). The aim of this study is the early detection of ASD risk, using a follow-up protocol, in children weighing less than 1500 g at birth or born before 32 weeks of gestation. Methods: This is a prospective longitudinal study in which a total of 133 very premature babies were monitored to the age of 2 years with the M-CHAT autism screening test and, in the event of a positive result, the Autism Diagnostic Observation Schedule (ADOS-2). Results: 53 cases (4 out of 10) screened positive, and the rest negative. Among the positives, the ADOS-2 was administered in 50 cases, of which 24 scored above the ASD cutoff point. The average age of detection was 25. 39 months. The results suggest an estimated prevalence of ASD in the very premature population of 18. 46 %. Conclusions: The application of the follow-up protocol in the very premature population is effective for early detection of ASD.
Note:	Altres ajuts: acords transformatius de la UAB
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Autism spectrum disorder ; Premature baby ; Low birth weight ; Early diagnosis ; Spanish follow-up protocol
Published in:	Brain & development (Amsterdam), Vol. 46, Núm. 10 (November 2024) , p. 368-372, ISSN 1872-7131
Related work:	Marín Soro, Marta, 2024, "Prematurity and Autism Spectrum Disorder", https://doi.org/10.34810/data1536, CORA.Repositori de Dades de Recerca, V1 https://doi.org/10.34810/data1536

DOI: 10.1016/j.braindev.2024.08.006

5 p, 676.9 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Neurociències (INc)
Articles > Research articles
Articles > Published articles