Clinical characteristics and predictors of complications and mortality in hospitalized octogenarian patients with COVID-19 : an ambispective study
Arroyo-Huidobro, Marta (Hospital Clínic i Provincial de Barcelona)
Pallares Fontanet, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Tebé, Cristian (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Simonetti, Antonella Francesca (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Pérez-López, Carlos (Consorci Sanitari Alt Pènedes i Garraf)
Abelenda-Alonso, Gabriela (Hospital Universitari de Bellvitge)
Rombauts, Alexander (Hospital Universitari de Bellvitge)
Oriol Bermúdez, Isabel (Consorci Sanitari Integral)
Izquierdo, Elisenda (Hospital de Viladecans)
Diaz-Brito, Vicens (Parc Sanitari Sant Joan de Déu)
Molist, Gemma (Hospital Universitari de Bellvitge)
Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya. BarcelonaTech)
Videla, Sebastián (Hospital Universitari de Bellvitge)
López Soto, Alfons (Hospital Clínic i Provincial de Barcelona)
Carratalà, Jordi (Hospital Universitari de Bellvitge)
Rodríguez Molinero, Alejandro (Consorci Sanitari Alt Penedes-Garraf)
Piulachs, Xavier
Pérez-Álvarez, Núria
Langohr, Klaus
Fernández Martínez, Daniel
Cortés, Jordi
Cobo, Erik
Besalú, Mireia
Hereu, Pilar
Garmendia, Leire
Videla, Sebastià
Serrano, Laura
Pérez, Andrea
Colom, Mireia
Cruz, Paula
González, Martha
Faura, Ana
Álvarez, María C.
Moreno, Encarna
Sanmartí, Montserrat
Aranda-Lobo, Judit
Gudiol, Carlota
Universitat Autònoma de Barcelona

Date:	2024
Abstract:	This the study describes the clinical presentation of COVID-19 and the risk factors for complications and death in octogenarian hospitalized patients across the different waves of the disease. The most frequently reported symptoms in hospitalized octogenarian patients were fever, cough, dyspnea, and asthenia with acute respiratory distress syndrome, renal failure, and delirium being the most frequent complications. Regarding complications, diabetes mellitus, heart failure, dyspnea, and higher baseline levels of creatinine were identified as risk factors, while a higher Barthel index and presence of cough were found to be protective. Age, dyspnea, abnormal bilateral chest x-ray, CRP, and sodium were identified as risk factors for death. These findings could be valuable for managing future pandemics by contributing to tailored interventions and strategies to reduce COVID-19 mortality and complications in this patient group.
Grants:	Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-01421
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Aged 80 and over ; COVID-19 ; Clinical complications ; Mortality ; Octogenarians ; Pandemic waves ; Risk factors
Published in:	European Geriatric Medicine, Vol. 15 Núm. 5 (october 2024) , p. 1477-1487, ISSN 1878-7657

DOI: 10.1007/s41999-024-01063-1
PMID: 39425809

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles