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Probiotics : A Potential Strategy for Preventing and Managing Cardiovascular Disease
López-Yerena, Anallely (Institut de Recerca Sant Pau)
de Santisteban, Victoria Marta (Institut de Recerca Sant Pau)
Badimon, Lina (Institut de Recerca Sant Pau)
Vilahur, Gemma (Institut de Recerca Sant Pau)
Padró, Teresa (Institut de Recerca Sant Pau)
Universitat Autònoma de Barcelona

Data: 2025
Resum: Probiotics are gaining recognition as a viable strategy for mitigating cardiovascular risk factors. Specifically, recent studies highlight their potential benefits in managing cholesterol levels, blood pressure, and inflammation, which are critical components in the prevention of cardiovascular diseases (CVD). This comprehensive review aims to elucidate the impact of probiotic consumption on major cardiovascular risk factors, including individuals with hypertension, type II diabetes mellitus, metabolic syndrome, hypercholesterolemia, and in secondary prevention in coronary artery disease. Scientific evidence based on human studies suggests that probiotic consumption is associated with positive effects on anthropometric measures, inflammation markers, blood pressure, glucose metabolism markers, lipid profiles, and endothelial function. However, these findings should be interpreted pragmatically and acknowledge the significant variability in results. This variability may be attributed to factors such as probiotic composition (single strain or multiple strains), the characteristics of the delivery matrix (food, capsules, and sachets), the duration of the intervention, the dosage regimen, and baseline health profiles of the participants. Incorporating probiotics as part of a comprehensive and healthy lifestyle approach can be considered a feasible strategy for both the prevention and management of CVD. However, further research is needed on factors influencing the effect of probiotics, such as: (i) optimal probiotic strain(s), (ii) appropriate dosage, (iii) duration of treatment, (iv) optimal delivery vehicle, and (v) sex-specific differences.
Ajuts: Agencia Estatal de Investigación PID2019-107160RB-I00
Agencia Estatal de Investigación PID2021-128891OB-I00
Drets: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Llengua: Anglès
Document: Article de revisió ; recerca ; Versió publicada
Matèria: Blood pressure ; Functional foods ; Inflammation ; Lipid profile
Publicat a: Nutrients, Vol. 17 Núm. 1 (january 2025) , p. 52, ISSN 2072-6643

DOI: 10.3390/nu17010052
PMID: 39796486


22 p, 1.2 MB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
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 Registre creat el 2025-10-01, darrera modificació el 2025-10-10



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