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| Pàgina inicial > Articles > Articles publicats > De novo genome assembly, inversion detection, and worldwide adaptation on the invasive species Styela plicata |
(Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) (Senckenberg Forschungsinstitut und Naturmuseum) (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) (Centre d'Estudis Avançats de Blanes) (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística)| Data: | 2025 |
| Resum: | Biological invasions are a major threat to biodiversity. However, genomic resources of invasive species are scarce, compromising the study of their invasive success and our ability to mitigate their effects. Here, we assemble and annotate the reference chromosome-level genome of the invasive ascidian Styela plicata, and complement it with whole genome sequencing data from 24 individuals worldwide. We developed and validated the novel method "individual Detection of linkage by Genotyping" (iDlG), that allowed identifying four large chromosomal inversions and assigning karyotypes at the individual level. The four inversions are polymorphic throughout the species' distribution range and are enriched with genes that potentially influence fitness in estuarine and harbor environments, where Styela plicata thrives. It was only after we removed the inversions that we could detect clear population structuring, both between and within oceans, driven by several candidate adaptive genes involved in osmoregulation and other functions. Moreover, we recovered three major mitogenomic lineages, two of them globally sympatric and one specific to a single population. Interestingly, mitochondrial lineages show associations with nuclear genes likely involved in correct mitochondrion distribution during cell division. Our study highlights the importance of generating annotated reference genomes and combining them with whole genome sequencing data across whole distribution ranges to identify species' structural and sequence variation for understanding complex evolutionary processes. |
| Ajuts: | Agencia Estatal de Investigación PID2020-118550RB Agencia Estatal de Investigación PID2023-146307OB Agencia Estatal de Investigación PRE-2018-085227 Generalitat de Catalunya 2021/SGR-01271 Generalitat de Catalunya 2021/SGR-00405 |
| Drets: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.  |
| Llengua: | Anglès |
| Document: | Article ; recerca ; Versió publicada |
| Publicat a: | Scientific reports, Vol. 15 (November 2025) , art. 40328, ISSN 2045-2322 |
