Home > Search Results: Pacin-Ruiz, Beatriz
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Results overview: Found 5 records in 0.02 seconds.
Articles, 4 records found
Research literature, 1 records found
Articles 4 records found  
1.
16 p, 1.9 MB Cross-sectional evaluation of circulating hepatitis B virus RNA and DNA : Different quasispecies? / García-García, Selene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tabernero, David (Instituto de Salud Carlos II) ; Gregori i Font, Josep (Instituto de Salud Carlos II) ; Vila, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pacín Ruiz, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Quer, Josep 1963- (Instituto de Salud Carlos II) ; Casillas, Rosario (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castillo-Ribelles, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferrer Costa, Roser (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ; Trejo-Zahínos, Jesús (Hospital Universitari Vall d'Hebron) ; Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ; Casis-Saez, Ernesto (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteban, Rafael (Instituto de Salud Carlos II) ; Riveiro Barciela, Mar (Instituto de Salud Carlos II) ; Buti, Maria (Instituto de Salud Carlos II) ; Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Different forms of pregenomic and other hepatitis B virus (HBV) RNA have been detected in patients' sera. These circulating HBV-RNAs may be useful for monitoring covalently closed circular DNA activity, and predicting hepatitis B e-antigen seroconversion or viral rebound after nucleos(t)ide analog cessation. [...]
2021 - 10.3748/wjg.v27.i41.7144
World Journal of Gastroenterology, Vol. 27 (november 2021) , p. 7144-7158  
Detailed record - Creative Commons
2.
18 p, 1.0 MB Hepatitis B Virus Variants with Multiple Insertions and/or Deletions in the X Open Reading Frame 3' End : Common Members of Viral Quasispecies in Chronic Hepatitis B Patients / García-García, Selene (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Caballero, Andrea (Hospital Universitari Vall d'Hebron) ; Tabernero, David (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Cortese, Maria Francesca (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Gregori i Font, Josep (Hospital Universitari Vall d'Hebron) ; Rodriguez-Algarra, Francisco (Queen Mary University of London) ; Quer, Josep 1963- (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron) ; Homs, Maria (Institut Català de la Salut) ; Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ; Pacín Ruiz, Beatriz (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Vila, Marta (Hospital Universitari Vall d'Hebron) ; Ferrer Costa, Roser (Hospital Universitari Vall d'Hebron) ; Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ; Buti, Maria (Hospital Universitari Vall d'Hebron) ; Rodríguez Frías, Francisco (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Deletions in the 3' end region of the hepatitis B virus (HBV) X open reading frame (HBX) may affect the core promoter (Cp) and have been frequently associated with hepatocellular carcinoma (HCC). The aim of this study was to investigate the presence of variants with deletions and/or insertions (Indels) in this region in the quasispecies of 50 chronic hepatitis B (CHB) patients without HCC. [...]
2022 - 10.3390/biomedicines10051194
Biomedicines, Vol. 10, Issue 5 (May 2022) , art. 1194  
Detailed record - Creative Commons
3.
13 p, 1.5 MB Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1 : Conservation and Variability / Pacín Ruiz, Beatriz (Hospital Universitari Vall d'Hebron) ; Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron) ; Tabernero, David (Hospital Universitari Vall d'Hebron) ; Sopena, Sara (Hospital Universitari Vall d'Hebron) ; Gregori i Font, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-García, Selene (Hospital Universitari Vall d'Hebron) ; Casillas, Rosario (Hospital Universitari Vall d'Hebron) ; Najarro-Centeno, Adrián (Hospital Universitari Vall d'Hebron) ; Aldama, Unai (Hospital Universitari Vall d'Hebron) ; Palom, Adriana (Hospital Universitari Vall d'Hebron) ; Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ; Galán, Anna (Hospital Universitari Vall d'Hebron) ; Vila, Marta (Hospital Universitari Vall d'Hebron) ; Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron) ; Quer, Josep 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Aseguinolaza, Gloria (Univerdad de Pamplona) ; Buti, Maria (Hospital Universitari Vall d'Hebron) ; Rodríguez Frías, Francisco (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The hepatitis delta virus (HDV) genome has an autocatalytic region called the ribozyme, which is essential for viral replication. The aim of this study was to use next-generation sequencing (NGS) to analyze the ribozyme quasispecies (QS) in order to study its evolution and identify highly conserved regions potentially suitable for a gene-silencing strategy. [...]
2022 - 10.3390/v14020215
Viruses, Vol. 14 (january 2022)  
Detailed record - Creative Commons
4.
11 p, 1.1 MB Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients / Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron) ; González, Carolina (Hospital Universitari Vall d'Hebron) ; Gregori i Font, Josep (Roche Diagnostics (Sant Cugat)) ; Casillas, Rosario (Hospital Universitari Vall d'Hebron) ; Carioti, Luca (University of Rome Tor Vergata) ; Guerrero Murillo, Mercedes (Hospital Universitari Vall d'Hebron) ; Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Godoy, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sopena, Sara (Hospital Universitari Vall d'Hebron) ; Yll, Marçal (Hospital Universitari Vall d'Hebron) ; Quer, Josep 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ; Lopez-Martinez, Rosa (Hospital Universitari Vall d'Hebron) ; Pacín Ruiz, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-García, Selene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteban, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tabernero, David (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Buti, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Patients with HBeAg-negative chronic infection (CI) have not been extensively studied because of low viremia. The HBx protein, encoded by HBX, has a key role in viral replication. Here, we analyzed the viral quasispecies at the 5' end of HBX in CI patients and compared it with that of patients in other clinical stages. [...]
2021 - 10.1038/s41598-021-83762-4
Scientific reports, Vol. 11 (february 2021)  
Detailed record - Creative Commons

Research literature 1 records found  
1.
Studying Hepatitis B and Hepatitis Delta viruses quasispecies by Next-generation sequencing : Conservation, variability, and interaction / Pacín Ruiz, Beatriz ; Cortese, Maria Francesca, dir. ; Rodríguez Frías, Francisco, dir.
El virus de l'hepatitis B (VHB) afecta uns 296 milions de persones arreu del món, més del 5% coinfectades amb el virus de l'hepatitis delta (VHD), causant l'hepatitis vírica més greu. El VHD presenta un domini d'ARN auto-catalític, la ribozima, i una regió que codifica per l'única proteïna viral, l'antigen delta (HDAg). [...]
El virus de la hepatitis B (VHB) afecta a unos 296 millones de personas, más del 5% coinfectadas con el virus de la hepatitis delta (VHD), causando la hepatitis vírica más grave. El VHD presenta un dominio de RNA auto-catalítico, la ribozima, y una región que codifica para la única proteína viral, denominada antígeno delta (HDAg). [...]
The Hepatitis B virus (HBV) affects around 296 million people worldwide. Of them, more than 5% are coinfected with Hepatitis delta virus (HDV), causing the most severe viral hepatitis. HDV is a viroid-like virus since it presents a catalytically active RNA portion known as ribozyme, and a region encoding for the unique viral protein, called delta antigen (HDAg). [...]
2023  
Detailed record - Creative Commons

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