Resultados globales: 25 registros encontrados en 0.02 segundos.
Artículos, Encontrados 20 registros
Documentos de investigación, Encontrados 5 registros
Artículos Encontrados 20 registros  1 - 10siguiente  ir al registro:
1.
6 p, 557.9 KB Interferon-γ-Inducible Protein 10 (IP-10) as a Screening Tool to Optimize Human Immunodeficiency Virus RNA Monitoring in Resource-Limited Settings / Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Casellas, Aina (Institut de Salut Global de Barcelona) ; Rupérez, María (Centro de Investigação em Saúde da Manhiça) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Maculuve, Sonia (Centro de Investigação em Saúde da Manhiça) ; Jairoce, Chenjerai (Centro de Investigação em Saúde da Manhiça) ; Paredes, Roger (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Naniche, Denise (Centro de Investigação em Saúde da Manhiça) ; Universitat Autònoma de Barcelona
Interferon-γ-inducible protein-10 is an affordable and easily quantifiable biomarker that can be used to accurately screen individuals on antiretroviral treatment (ART) for detectable viremia, optimizing the use of costly viral load determinations required to monitor ART in low-income countries. [...]
2017 - 10.1093/cid/cix600
Clinical Infectious Diseases, Vol. 65 (july 2017) , p. 1670-1675  
2.
12 p, 653.9 KB HIV-1 Gag mutations alone are sufficient to reduce darunavir susceptibility during virological failure to boosted PI therapy / Blanch Lombarte, Oscar (Institut Germans Trias i Pujol) ; Santos, José Ramón (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Peña, Ruth (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Jiménez Moyano, Esther (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Prado, Julia G. (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Virological failure (VF) to boosted PIs with a high genetic barrier is not usually linked to the development of resistance-associated mutations in the protease gene. From a cohort of 520 HIV-infected subjects treated with lopinavir/ritonavir or darunavir/ritonavir monotherapy, we retrospectively identified nine patients with VF. [...]
2020 - 10.1093/jac/dkaa228
Journal of Antimicrobial Chemotherapy, Vol. 75 (june 2020) , p. 2535-2546  
3.
12 p, 401.2 KB Balances : a New Perspective for Microbiome Analysis / Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Egozcue, J. J. (Universitat Politècnica de Catalunya) ; Pawlowsky-Glahn, Vera (Universitat de Girona) ; Paredes, Roger (Universitat Autònoma de Barcelona. Departament de Medicina) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Calle, M. Luz (Universitat de Vic - Universitat Central de Catalunya)
We propose a new algorithm for the identification of microbial signatures. These microbial signatures can be used for diagnosis, prognosis, or prediction of therapeutic response based on an individual's specific microbiota. [...]
2018 - 10.1128/mSystems.00053-18
mSystems, Vol. 3 (july 2018)  
4.
17 p, 6.0 MB Evolution of the gut microbiome following acute HIV-1 infection / Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pastor, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guillén Montalbán, Yolanda (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Langhorst, Jost (University of Duisburg-Essen. Chair for Integrative Medicine and translationale Gastroenterology, Klinikum Bamberg) ; Parera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Calle, Maria Luz (Universitat de Vic - Universitat Central de Catalunya) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Naniche, Denise (Centro de Investigação em Saúde da Manhiça (CISM)) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
In rhesus macaques, simian immunodeficiency virus infection is followed by expansion of enteric viruses but has a limited impact on the gut bacteriome. To understand the longitudinal effects of HIV-1 infection on the human gut microbiota, we prospectively followed 49 Mozambican subjects diagnosed with recent HIV-1 infection (RHI) and 54 HIV-1-negative controls for 9-18 months and compared them with 98 chronically HIV-1-infected subjects treated with antiretrovirals (n = 27) or not (n = 71). [...]
2019 - 10.1186/s40168-019-0687-5
Microbiome, Vol. 7 (may 2019)  
5.
15 p, 3.9 MB Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection / Guillén Montalbán, Yolanda. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Zevin, Alexander (University of Washington) ; Rocafort, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Parera, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez, C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Arumí, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Estany Quera, Carla (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Coll, J. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bravo, I. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Herrero, C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Saz, J. (BCN Checkpoint) ; Sirera, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Torrella Domingo, Adriana (Hospital Universitari Vall d'Hebron) ; Navarro Mercadé, Jordi (Hospital Universitari Vall d'Hebron) ; Crespo, M. (Infectious Diseases Unit. Internal Medicine Department. Complexo Hospitalario Universitario. Vigo. IIS Galicia Sur) ; Negredo Puigmal, Eugènia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Brander, Christian. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Calle, M.L. (Universitat de Vic - Universitat Central de Catalunya) ; Klatt, N.R. (University of Washington) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Human immunodeficiency virus (HIV)-1 infection causes severe gut and systemic immune damage, but its effects on the gut microbiome remain unclear. Previous shotgun metagenomic studies in HIV-negative subjects linked low-microbial gene counts (LGC) to gut dysbiosis in diseases featuring intestinal inflammation. [...]
2019 - 10.1038/s41385-018-0083-7
Mucosal Immunology, Vol. 12 Núm. 1 (january 2019) , p. 232-246  
6.
13 p, 4.9 MB Earlier initiation of antiretroviral treatment coincides with an initial control of the HIV-1 sub-subtype F1 outbreak among men-having-sex-with-men in Flanders, Belgium / Vinken, L. (Laboratory of Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Rega Institute for Medical Research. KU Leuven) ; Fransen, K. (Institute of Tropical Medicine Antwerp (Bèlgica)) ; Cuypers, L. (Laboratory of Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Rega Institute for Medical Research. KU Leuven) ; Alexiev, I. (National Reference Confirmatory Laboratory of HIV. National Center of Infectious and Parasitic Diseases) ; Balotta, C. (Infectious Diseases and Immunopathology Section. 'L. Sacco' Department of Biomedical and Clinical Sciences. 'L. Sacco' Hospital. University of Milan) ; Debaisieux, L. (AIDS Reference Laboratory. CUB-Hopital Erasme. Université Libre de Bruxelles) ; Seguin-Devaux, C. (Laboratory of Retrovirology. Department of Infection and Immunity. Luxembourg Institute of Health) ; Ribas, S.G. (Institute of Tropical Medicine Antwerp (Bèlgica)) ; Gomes, P. (Centro de Investigação Interdisciplinar Egas Moniz. Instituto Universitário Egas Moniz) ; Incardona, F. (EuResist Network GEIE) ; Kaiser, R. (Institute of Virology. University of Cologne) ; Ruelle, J. (Unit of Medical Microbiology. Institute of Experimental and Clinical Research. Université Catholique de Louvain) ; Sayan, M. (Research Center of Experimental Health Sciences. Near East University) ; Paraschiv, S. (Molecular Diagnostics Laboratory. National Institute for Infectious Diseases 'Matei Bals') ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Peeters, M. (UMI 233 TransVIHMI/INSERM1175. Institut de Recherche pour le Développement. University of Montpellier) ; Sönnerborg, A. (Division of Clinical Microbiology. Department of Laboratory Medicine. Karolinska Institutet) ; Vancutsem, E. (AIDS Reference Laboratory. Department of Microbiology and Infection Control. Universitair Ziekenhuis Brussel) ; Vandamme, A.M. (Unidade de Microbiologia. Center for Global Health and Tropical Medicine. Instituto de Higiene e Medicina Tropical. Universidade Nova de Lisboa) ; Van den Wijngaert, S. (AIDS Reference Laboratory. Department of Microbiology. Saint-Pierre University Hospital) ; Van Ranst, M. (AIDS Reference Laboratory. University Hospitals Leuven) ; Verhofstede, C. (AIDS Reference Laboratory. Department of Clinical Chemistry. Microbiology and Immunology. Ghent University) ; Stadler, T. (Swiss Institute of Bioinformatics) ; Lemey, P. (Laboratory of Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Rega Institute for Medical Research. KU Leuven) ; Van Laethem, K. (AIDS Reference Laboratory. University Hospitals Leuven) ; Universitat Autònoma de Barcelona
Human immunodeficiency virus type 1 (HIV-1) non-B subtype infections occurred in Belgium since the 1980s, mainly amongst migrants and heterosexuals, whereas subtype B predominated in men-having-sex-with-men (MSM). [...]
2019 - 10.3389/fmicb.2019.00613
Frontiers in microbiology, Vol. 10 (march 2019) , p. 613  
7.
15 p, 676.0 KB Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers / Rosás Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Llano, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz-Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fernández, Marco A. (Institut Germans Trias i Pujol) ; Cobarsi, Patricia (Institut Germans Trias i Pujol) ; Crespo, Manel (Complexo Hospitalario Universitario de Vigo) ; Dorrell, Lucy (Nuffield Department of Medicine, University of Oxford) ; del Romero, Jorge (Centro Sanitario Sandoval, Madrid) ; Alcami, Jose (Instituto de Salud Carlos III) ; Paredes, Roger (Universitat Autònoma de Barcelona. Departament de Medicina) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
A few individuals can control HIV infection without the need for antiretroviral treatment and are referred to as HIV controllers. We have studied HIV controllers who suddenly lose this ability and present with high in vivo viral replication and decays in their CD4 + T-cell counts to identify potential immune and virological factors that were responsible for initial virus control. [...]
2019 - 10.1128/JVI.01436-18
Journal of Virology, Vol. 93 (february 2019)  
8.
14 p, 954.2 KB Plasma HIV-1 Tropism and the Risk of Short- Term Clinical Progression to AIDS or Death / Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cozzi-Lepri, Alessandro (Royal Free Hospital, London) ; Phillips, Andrew (Royal Free Hospital, London) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bickel, Markus (Goethe University) ; Sedlacek, Dalibor (Charles University Hospital, Plzen, Česka ́Republika) ; Zilmer, Kai (West-Tallinn Central Hospital, Tallinn) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Lundgren, Jens D. (University of Copenhagen) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; EuroSIDA in EuroCOORD ; Universitat Autònoma de Barcelona
Objective. To investigate if plasma HIV-1 tropism testing could identify subjects at higher risk for clinical progression and death in routine clinical management. Design. Nested case-control study within the EuroSIDA cohort. [...]
2017 - 10.1371/journal.pone.0166613
PloS one, 2017, p. 1-14  
9.
1 p, 41.2 KB A21 HIV-1 sub-subtype F1 outbreak among MSM in Belgium / Vinken, L. ; Fransen, K. ; Pineda-Peña, A.C. ; Alexiev, I. ; Balotta, C. ; Debaisieux, L. ; Devaux, C. ; García Ribas, S. ; Gomes, P. ; Incardona, F. ; Kaiser, R ; Ruelle, J. ; Sayan, M. ; Paraschiv, S. ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Peeters, M. ; Sonnerborg, A. ; Vancutsem, E. ; Van den Wijngaert, S. ; Van Ranst, M. ; Verhofstede, C. ; Vandamme, A.-M. ; Lemey, P. ; Van Laethem, K. ; Universitat Autònoma de Barcelona
2017 - 10.1093/ve/vew036.020
Virus Evolution, Vol. 3 (march 2017)  
10.
9 p, 820.3 KB Oral microbiome in HIV-associated periodontitis / Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Guillén Montalbán, Yolanda (Universitat Autònoma de Barcelona) ; Peterson, Jessica (Emory University. School of Medicine. Division of Infectious Diseases) ; Reznik, David (Emory University. School of Medicine. Division of Infectious Diseases) ; Harris, Erica V. (Emory University. Department of Biology) ; Joseph, Sandeep J. (Emory University. School of Medicine. Division of Infectious Diseases) ; Rivera, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kannanganat Sidharthan, Sunil (Emory University. School of Medicine. Division of Infectious Diseases) ; Amara, Rama (Emory University. School of Medicine. Division of Infectious Diseases) ; Nguyen, Minh Ly (Emory University. School of Medicine. Division of Infectious Diseases) ; Mutembo, Simon (Zàmbia. Ministry of Health) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Read, Timothy D. (Emory University. School of Medicine. Division of Infectious Diseases) ; Marconi, Vincent C. (Emory University. School of Medicine. Division of Infectious Diseases)
Supplemental Digital Content is available in the text HIV-associated periodontal diseases (PD) could serve as a source of chronic inflammation. Here, we sought to characterize the oral microbial signatures of HIV+ and HIV- individuals at different levels of PD severity. [...]
2017 - 10.1097/MD.0000000000005821
Medicine, Vol. 96, issue 12 (March 2017) , e5821  

Artículos : Encontrados 20 registros   1 - 10siguiente  ir al registro:
Documentos de investigación Encontrados 5 registros  
1.
135 p, 4.5 MB Gut microbiome in HIV-1 infection / Rocafort Juncà, Muntsa ; Paredes i Deiros, Roger, dir. ; Noguera i Julian, Marc, dir. ; Coll Figa, Pedro, dir. ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Una vegada el Virus de la Immunodeficiència Humana tipus 1 (en anglès HIV-1) infecta l'organisme hoste es produeix una ràpida i severa destrucció del teixit limfoide associat a tracte gastrointestinal que inclou, entre d'altres, significants pèrdues cel·lulars del sistema immunitari i epitelial de l'hoste. [...]
Soon after Human Immunodeficiency Virus type 1 (HIV-1) infection, a severe and rapid depletion of the gut-associated lymphoid tissue occurs, including significant loss of both, immune and epithelial host cells. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  
2.
164 p, 2.3 MB Next-Generation Virus Genotyping for HIV-1 Surveillance and Clinical Management / Casadellà Fontdevila, Maria ; Paredes i Deiros, Roger, dir. ; Farrés i Vicén, Jaume, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Tot i que la infecció pel virus de la immunodeficiència humana de tipus 1 (VIH-1) roman sense cura, la teràpia antiretroviral és capaç de bloquejar de manera persistent la replicació viral, limitant el dany al sistema immunitari. [...]
Although HIV-1 infection cannot be cured, antiretroviral therapy is able to persistently block virus replication, limiting the damage on the immune system. This can prevent and/or revert immune deterioration in most subjects, prolonging life expectancy and increasing its quality. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016
2 documentos
3.
173 p, 2.2 MB Clinical impact of HIV-1 resistance against nonnucleoside analogue reverse transcriptase Inhibitors / Llibre Codina, Josep Maria ; Paredes i Deiros, Roger, dir. ; Clotet, Bonaventura, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
Els inhibidors de la transcriptassa inversa no anàlegs de nucleòsids (ITINAN) s'utilitzen sovint en el tractament antiretroviral (TAR) per la seva eficàcia i simplicitat. La resistència està causada per mutacions específiques a posicions de resistència. [...]
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are popular components of antiretroviral therapy due to their efficacy and simplicity. Resistance is caused only by specific mutations at drug-resistance positions. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2015  
4.
256 p, 3.4 MB Clinical value of massive Parallel HIV-1 sequencing in antiretroviral treatment-experienced subjects / Pou Gonzàlez, Christian ; Paredes i Deiros, Roger, dir. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Farrés i Vicén, Jaume, tut. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Els test de resistència al antiretrovirals són utilitzats en la pràctica clínica per la personalització del tractament antiretroviral (TARV) de les persones infectades pel VIH-1. La seqüenciació poblacional (SP) és la tècnica més emprada pel genotipat del VIH-1 obtenint una bona correlació amb la resposta clínica dels pacients. [...]
Los ensayos de resistencia a los antiretrovirales son utilizados en la práctica clínica para la personalización del tratamiento antirretroviral (TARV) de las personas infectadas por el VIH-1. La secuenciación poblacional (SP) es la técnica más utilizada para el genotipado del VIH-1 obteniendo una buena correlación con la respuesta clínica de los pacientes. [...]
Drug resistance testing is utilized in the clinical routine to personalize ART of HIV-1 infected people. Population sequencing is employed for HIV-1 genotyping obtaining good correlations with clinical outcomes. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
5.
301 p, 3.1 MB Clinical implications of minority HIV-1 resistant variants / Paredes i Deiros, Roger ; Kuritzkes, Daniel R., dir. (Harvard Medical School) ; Clotet, Bonaventura, dir. (Universitat Autònoma de Barcelona. Departament de Medicina)
Aquesta tesi doctoral per compendi de publicacions avalua la importància clínica de les variants del VIH-1 minoritàries que alberguen mutacions de resistència. La primera publicació presenta una avaluació sistemàtica de la PCR específica d'al·lel (ASPCR) com a eina per detectar variants víriques minoritàries que amb mutacions de resistència a la transcriptasa inversa (M184V, M184I) i proteasa (regions de D30N), així com a la envolta (V38A). [...]
Bellaterra : Universitat Autònoma de Barcelona, 2009  

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