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Articles, 14 registres trobats
Articles 14 registres trobats  1 - 10següent  anar al registre:
1.
19 p, 2.4 MB Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations / Temprano-Sagrera, Gerard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Sitlani, Collen M. (University of Washington) ; Bone, William P. (University of Pennsylvania) ; Martín Bórnez, Miguel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Voight, Benjamin F. (University of Pennsylvania Perelman School of Medicine) ; Morrison, Alanna C. ; Damrauer, Scott M. ; de Vries, Paul S. ; Smith, Nicholas L. ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Dehghan, Abbas ; Heath, Adam S. ; Reiner, Alex P. ; Johnson, Andrew ; Richmond, Anne ; Peters, Annette ; van Hylckama Vlieg, Astrid ; McKnight, Barbara ; Psaty, Bruce M. ; Hayward, Caroline ; Ward-Caviness, Cavin ; O'Donnell, Cristopher ; Chasman, Daniel ; Strachan, David P. ; Tregouet, David A. ; Mook-Kanamori, Dennis ; Gill, Dipender ; Thibord, Florian ; Asselbergs, Folkert W. ; Leebeek, Frank W. G. ; Rosendaal, Frits R. ; Davies, Gail ; Homuth, Georg ; Temprano, Gerard ; Campbell, Harry ; Taylor, Herman A. ; Bressler, Jan ; Huffman, Jennifer E. ; Rotter, Jerome I. ; Yao, Jie ; Wilson, James F. ; Bis, Joshua C. ; Hahn, Julie M. ; Desch, Karl C. ; Wiggins, Kerri L. ; Raffield, Laura M. ; Bielak, Lawrence F. ; Yanek, Lisa R. ; Kleber, Marcus E. ; Mueller, Martina ; Kavousi, Maryam ; Mangino, Massimo ; Liu, Melissa ; Brown, Michael R. ; Conomos, Matthew P. ; Jhun, Min-A. ; Chen, Ming-Huei ; de Maat, Moniek P. M. ; Pankratz, Nathan ; Smith, Nicholas L. ; Peyser, Patricia A. ; Elliot, Paul ; Wei, Peng ; Wild, Philipp S. ; Morange, Pierre E. ; van der Harst, Pim ; Yang, Qiong ; Le, Ngoc-Quynh ; Marioni, Riccardo ; Li, Ruifang ; Damrauer, Scott M. ; Cox, Simon R. ; Trompet, Stella ; Felix, Stephan B. ; Völker, Uwe ; Tang, Weihong ; Koenig, Wolfgang ; Jukema, J. Wouter ; Guo, Xiuqing ; Lindstrom, Sara ; Wang, Lu ; Smith, Erin N. ; Gordon, William ; van Hylckama Vlieg, Astrid ; de Andrade, Mariza ; Brody, Jennifer A. ; Pattee, Jack W. ; Haessler, Jeffrey ; Brumpton, Ben M. ; Suchon, Pierre ; Chen, Ming-Huei ; Turman, Constance ; Germain, Marine ; Wiggins, Kerri L. ; MacDonald, James ; Braekkan, Sigrid K. ; Armasu, Sebastian M. ; Pankratz, Nathan ; Jackson, Rabecca D. ; Nielsen, Jonas B. ; Giulianini, Franco ; Puurunen, Marja K. ; Ibrahim, Manal ; Heckbert, Susan R. ; Bammler, Theo K. ; Frazer, Kelly A. ; McCauley, Bryan M. ; Taylor, Kent ; Pankow, James S. ; Reiner, Alexander P. ; Gabrielsen, Maiken E. ; Deleuze, Jean-François ; O'Donnell, Chris J. ; Kim, Jihye ; McKnight, Barbara ; Kraft, Peter ; Hansen, John-Bjarne ; Rosendaal, Frits R. ; Heit, John A. ; Psaty, Bruce M. ; Tang, Weihong ; Kooperberg, Charles ; Hveem, Kristian ; Ridker, Paul M. ; Morange, Pierre-Emmanuel ; Johnson, Andrew D. ; Kabrhel, Christopher ; Trégouët, David-Alexandre ; Smith, Nicholas L. ; Malik, Rainer ; Chauhan, Ganesh ; Traylor, Matthew ; Sargurupremraj, Muralidharan ; Okada, Yukinori ; Mishra, Aniket ; Rutten-Jacobs, Loes ; Giese, Anne-Katrin ; van der Laan, Sander W. ; Gretarsdottir, Solveig ; Anderson, Christopher D. ; Chong, Michael ; Adams, Hieab HH. ; Ago, Tetsuro ; Almgren, Peter ; Amouyel, Philippe (Institut Pasteur de Lille) ; Ay, Hakan ; Bartz, Traci M. ; Benavente, Oscar R. ; Bevan, Steve ; Boncoraglio, Giorgio B. ; Brown, Robert D. ; Butterworth, Aadam S. ; Carrera, Caty ; Carty, Cara L. ; Chen, Wei-Min ; Cole, John W. ; Correa, Adolfo ; Cotlarciuc, Ioanna ; Cruchaga, Carlos ; Danesh, John ; de Bakker, Paul I. W. ; DeStefano, Anita L. ; den Hoed, Marcel ; Duan, Qing ; Engelter, Stefan T. ; Falcone, Guido J. ; Gottesman, Rebecca F. ; Grewal, Raji P. ; Gudnason, Vilmundur ; Gustafsson, Stefan ; Haessler, Jeffrey ; Harris, Tamara B. ; Hassan, Ahamad ; Havulinna, Aki S. ; Heckbert, Susan R. ; Holliday, Elizabeth G. ; Howard, George ; Hsu, Fang-Chi ; Hyacinth, Hyacinth I. ; Arfan Ikram, M. ; Ingelsson, Erik ; Irvin, Marguerite R. ; Jian, Xueqiu ; Jiménez-Conde, Jordi ; Johnson, Julie A. ; Jukema, J. Wouter ; Kanai, Masahiro ; Keene, Keith L. ; Kissela, Brett M. ; Kleindorfer, Dawn O. ; Kooperberg, Charles ; Kubo, Michiaki ; Lange, Leslie A. ; Langefeld, Carl D. ; Langenberg, Claudia ; Launer, Lenore J. ; Lee, Jin-Moo ; Lemmens, Robin ; Leys, Didier ; Lewis, Cathryn M. ; Lin, Wei-Yu ; Lindgren, Arne G. ; Lorentzen, Erik ; Magnusson, Patrik K. ; Maguire, Jane ; Manichaikul, Ani ; McArdle, Patrick F. ; Meschia, James F. ; Mitchell, Braxton D. ; Mosley, Thomas H. ; Nalls, Michael A. ; Ninomiya, Toshiharu ; O'Donnell, Martin J. ; Psaty, Bruce M. ; Pulit, Sara L. ; Rannikmäe, Kristiina ; Reiner, Alexander P. ; Rexrode, Kathryn M. ; Rice, Kenneth ; Rich, Stephen S. ; Ridker, Paul M. ; Rost, Natalia S. ; Rothwell, Peter M. ; Rotter, Jerome I. ; Rundek, Tatjana ; Sacco, Ralph L. ; Sakaue, Saori ; Sale, Michele M. ; Salomaa, Veikko ; Sapkota, Bishwa R. ; Schmidt, Reinhold ; Schmidt, Carsten O. ; Schminke, Ulf ; Sharma, Pankaj ; Slowik, Agnieszka ; Sudlow, Cathie L. M. ; Tanislav, Christian ; Tatlisumak, Turgut ; Taylor, Kent D. ; Thijs, Vincent N. S. ; Thorleifsson, Gudmar ; Thorsteinsdottir, Unnur ; Tiedt, Steffen ; Trompet, Stella ; Tzourio, Christophe ; van Duijn, Cornelia M. ; Walters, Matthew ; Wareham, Nicholas J. ; Wassertheil-Smoller, Sylvia ; Wilson, James G. ; Wiggins, Kerri L. ; Yang, Qiong ; Yusuf, Salim ; Amin, Najaf ; Aparicio, Hugo S. ; Arnett, Donna K. ; Attia, John ; Beiser, Alexa S. ; Berr, Claudine ; Buring, Julie E. ; Bustamante, Mariana ; Caso, Valeria ; Cheng, Yu-Ching ; Hoan Choi, Seung ; Chowhan, Ayesha ; Cullell, Natalia ; Dartigues, Jean-François ; Delavaran, Hossein ; Delgado, Pilar ; Dörr, Marcus ; Engström, Gunnar ; Ford, Ian ; Gurpreet, Wander S. ; Hamsten, Anders ; Heitsch, Laura ; Hozawa, Aatsushi ; Ibanez, Laura ; Ilinca, Andrea ; Ingelsson, Martin ; Iwasaki, Motoki ; Jackson, Rebecca D. ; Jood, Katarina ; Jousilahti, Pekka ; Kaffashian, Sara ; Kalra, Lalit ; Kamouchi, Masahiro ; Kitazono, Takanari ; Kjartansson, Olafur ; Kloss, Manja ; Koudstaal, Peter J. ; Krupinski, Jerzy ; Labovitz, Daniel L. ; Laurie, Cathy C. ; Levi, Christhoper R. ; Li, Linxin ; Lind, Lars ; Lindgren, Cecilia M. ; Lioutas, Vasileios ; Mei Liu, Yong ; Lopez, Oscar L. ; Makoto, Hirata ; Martinez-Majander, Nicolas ; Matsuda, Koichi ; Minegishi, Naoko ; Montaner, Joan ; Morris, Andrew P. ; Muiño, Elena ; Müller-Nurasyid, Martina ; Norrving, Bo ; Ogishima, Soichi ; Parati, Eugenio A. ; Reddy Peddareddygari, Leema ; Pedersen, Nancy L. ; Pera, Joanna ; Perola, Markus ; Pezzini, Alessandro ; Pileggi, Silvana ; Rabionet, Raquel ; Riba-Llena, Iolanda ; Ribasés, Marta ; Romero, Jose R. ; Roquer, Jaume ; Rudd, Anthony G. ; Sarin, Antti-Pekka ; Sarju, Ralhan ; Sarnowski, Chloe ; Sasaki, Makoto ; Satizabal, Claudia L. ; Satoh, Mamoru ; Sattar, Naveed ; Sawada, Norie ; Sibolt, Gerli ; Sigurdsson, Ásgeir ; Smith, Albert ; Sobue, Kenji ; Soriano-Tárraga, Carolina ; Stanne, Tara ; Colin Stine, O. ; Stott, David J. ; Strauch, Konstantin ; Takai, Takako ; Tanaka, Hideo ; Tanno, Kozo ; Teumer, Alexander ; Tomppo, Liisa ; Torres-Aguila, Nuria P. ; Touze, Emmanuel ; Tsugane, Shoichiro ; Uitterlinden, Aandre G. ; Valdimarsson, Einar M. ; van der Lee, Sven J. ; Völzke, Henry ; Wakai, Kenji ; Weir, David ; Williams, Stephen R. ; Wolfe, Charles D.A. ; Wong, Quenna ; Xu, Huichun ; Yamaji, Taiki ; Sanghera, Dharambir K. ; Melander, Olle ; Jern, Christina ; Strbian, Daniel ; Fernandez-Cadenas, Israel ; Longstreth, W.T. ; Rolfs, Arndt ; Hata, Jun ; Woo, Daniel ; Rosand, Jonathan ; Pare, Guillaume ; Hopewell, Jemma C. ; Saleheen, Danish ; Stefansson, Kari ; Worrall, BradfordB. ; Kittner, Steven J. ; Seshadri, Sudha ; Fornage, Myriam ; Markus, Hugh S. ; Howson, Joana M. M. ; Kamatani, Yoichiro ; Debette, Stephanie ; Dichgans, Martin ; Universitat Autònoma de Barcelona
Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. [...]
2022 - 10.1111/jth.15698
Journal of Thrombosis and Haemostasis, Vol. 20 Núm. 6 (01 2022) , p. 1331-1349  
2.
10 p, 556.3 KB Nomograms including the UBC® Rapid test to detect primary bladder cancer based on a multicentre dataset / Meisl, Christina J. (Department of Urology. Charité - Universitätsmedizin Berlin. Corporate Member of Freie Universität Berlin. Humbold-Universität zu Berlin. and Berlin Institute of Health) ; Karakiewicz, Pierre I. (University of Montreal. Department of Surgery) ; Einarsson, Roland (IDL Biotech) ; Koch, Stefan (Brandenburg Medical School Theodor Fontane) ; Hallmann, Steffen (HELIOS Hospital Bad Saarow. Department of Urology) ; Weiß, Sarah (HELIOS Hospital Bad Saarow. Department of Urology) ; Hemdan, Tammer (Uppsala University. Department of Surgical Sciences) ; Malmström, Per-Uno (Uppsala University. Department of Surgical Sciences) ; Styrke, Johan (Umeå University. Department of Surgical and Perioperative Sciences. Urology and Andrology) ; Sherif, Amir (Umeå University. Department of Surgical and Perioperative Sciences. Urology and Andrology) ; Hasan, Mudhar N. (Danderyd Hospital. Department of Urology) ; Pichler, Renate (Medical University Innsbruck. Department of Urology) ; Tulchiner, Gennadi (Medical University Innsbruck. Department of Urology) ; Palou, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Rodríguez Faba, Óscar (Institut d'Investigació Biomèdica Sant Pau) ; Hennenlotter, Jörg (University Hospital Tübingen. Department of Urology) ; Stenzl, Arnulf (University Hospital Tübingen. Department of Urology) ; Ritter, René (Diakonie-Klinikum Stuttgart. Department of Urology) ; Niegisch, Günter (Heinrich Heine University Düsseldorf. Department of Urology. Faculty of Medicine) ; Grunewald, Camilla M. (Heinrich Heine University Düsseldorf. Department of Urology. Faculty of Medicine) ; Schlomm, Thorsten (Department of Urology. Charité - Universitätsmedizin Berlin. Corporate Member of Freie Universität Berlin. Humbold-Universität zu Berlin. and Berlin Institute of Health) ; Friedersdorff, Frank (Evangelisches Krankenhaus Königin Elisabeth Herzberge. Department of Urology) ; Barski, Dimitri (Rheinland Klinikum Neuss. Department of Urology) ; Otto, Thomas (University of Duisburg-Essen. Medical Faculty) ; Gössl, Andreas (HELIOS Hospital Krefeld. Department of Urology) ; Arndt, Christian (HELIOS Hospital Krefeld. Department of Urology) ; Esuvaranathan, Kesavan (National University Hospital. Department of Urology) ; Kesavan, Nisha R. (National University Hospital. Department of Urology) ; Zhijiang, Zang (National University Hospital. Department of Urology) ; Kramer, Mario W. (University Hospital Schleswig-Holstein Campus Lübeck. Department of Urology) ; Hennig, Martin J.P. (University Hospital Schleswig-Holstein Campus Lübeck. Department of Urology) ; Ecke, Thorsten H. (HELIOS Hospital Bad Saarow. Department of Urology) ; Universitat Autònoma de Barcelona
Objectives: To evaluate the clinical utility of the urinary bladder cancer antigen test UBC Rapid for the diagnosis of bladder cancer (BC) and to develop and validate nomograms to identify patients at high risk of primary BC. [...]
2022 - 10.1111/bju.15677
BJU International, Vol. 130 Núm. 6 (december 2022) , p. 754-763  
3.
7 p, 885.1 KB Biomarker-guided implementation of the KDIGO guidelines to reduce the occurrence of acute kidney injury in patients after cardiac surgery (PrevAKI-multicentre) : protocol for a multicentre, observational study followed by randomised controlled feasibility trial / Küllmar, Mira (Universitatsklinikum Munster) ; Massoth, Christina (Universitatsklinikum Munster) ; Ostermann, Marlies (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ; Campos, Sara (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ; Grau Novellas, Neus (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ; Thomson, Gary (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ; Haffner, Michael (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ; Arndt, Christian (University Hospital of Giessen and Marburg (Alemanya)) ; Wulf, Hinnerk (Philipps-Universitat Marburg Fachbereich Medizin) ; Irqsusi, Marc (Philipps-Universitat Marburg Fachbereich Medizin) ; Monaco, Fabrizio (Scientific Institute San Raffaele) ; Di Prima, Ambra (Scientific Institute San Raffaele) ; García Álvarez, Mercedes (Institut d'Investigació Biomèdica Sant Pau) ; Italiano, Stefano (Institut d'Investigació Biomèdica Sant Pau) ; Cegarra Sanmartin, Virginia (Institut d'Investigació Biomèdica Sant Pau) ; Kunst, Gudrun (King's College London) ; Nair, Shrijit (King's College London) ; L'acqua, Camilla (Centro Cardiologico Monzino IRCCS) ; Hoste, Eric A J (Universiteit Gent) ; Vandenberghe, Wim (Universiteit Gent) ; Honore, Patrick M (CHU Brugmann) ; Kellum, John (University of Pittsburgh) ; Forni, Lui (Royal Surrey County Hospital NHS Trust) ; Grieshaber, Philippe (Justus Liebig Universität Giessen Fachbereich Medizin) ; Weiss, Raphael (University Hospital of Münster (Alemanya)) ; Gerss, Joachim (Westfälische Wilhelms-Universität Münster) ; Wempe, Carola (Universitatsklinikum Munster) ; Meersch, Melanie (Universitatsklinikum Munster) ; Zarbock, Alexander (Universitatsklinikum Munster) ; Universitat Autònoma de Barcelona
Acute kidney injury (AKI) is a frequent complication after cardiac surgery with adverse short-term and long-term outcomes. Although prevention of AKI (PrevAKI) is strongly recommended, the optimal strategy is uncertain. [...]
2020 - 10.1136/bmjopen-2019-034201
BMJ open, Vol. 10 Núm. 4 (june 2020) , p. e034201  
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11 p, 897.2 KB MRI Radiomic Signature of White Matter Hyperintensities Is Associated With Clinical Phenotypes / Bretzner, Martin (University of Lille) ; Bonkhoff, Anna K. (Massachusetts General Hospital) ; Schirmer, Markus D. (Massachusetts General Hospital) ; Hong, Sungmin (Massachusetts General Hospital) ; Dalca, Adrian V. (Massachusetts Institute of Technology) ; Donahue, Kathleen L. (Massachusetts General Hospital) ; Giese, Anne-Katrin (Massachusetts General Hospital) ; Etherton, Mark R. (Massachusetts General Hospital) ; Rist, Pamela M. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Nardin, Marco (Massachusetts General Hospital) ; Marinescu, Razvan (Massachusetts Institute of Technology) ; Wang, Clinton (Massachusetts Institute of Technology) ; Regenhardt, Robert W. (Massachusetts General Hospital) ; Leclerc, Xavier (University of Lille) ; Lopes, Renaud (Institut Pasteur de Lille) ; Benavente, Oscar R. (Department of Medicine, University of British Columbia) ; Cole, John W. (Department of Neurology, University of Maryland School of Medicine a) ; Donatti, Amanda (School of Medical Sciences, University of Campinas (Brasil)) ; Griessenauer, Christoph J. (Paracelsus Medical University) ; Heitsch, Laura (Department of Neurology, Washington University School of Medicine) ; Holmegaard, Lukas (Sahlgrenska Academy at University of Gothenburg) ; Jood, Katarina (University of Gothenburg) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Kittner, Steven J. (Department of Neurology, University of Maryland School of Medicine) ; Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ; Levi, Christopher R. (Department of Neurology, John Hunter Hospital) ; McArdle, Patrick F. (Department of Medicine, University of Maryland School of Medicine) ; McDonough, Caitrin W. (Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida) ; Meschia, James F. (Mayo Clinic (Estats Units d'Amèrica)) ; Phuah, Chia-Ling (Department of Neurology, Washington University School of Medicine) ; Rolfs, Arndt (Centogene (Alemanya)) ; Ropele, Stefan (Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz) ; Rosand, Jonathan (Massachusetts General Hospital) ; Roquer, Jaume (Department of Neurology, University of Miami) ; Rundek, Tatjana (Department of Neurology, University of Miami) ; Sacco, Ralph L. (Department of Neurology University of Miami) ; Schmidt, Reinhold (Department of Neurology, Medical University of Graz) ; Sharma, Pankaj (St. Peter's Hospitals (Regne Unit)) ; Slowik, Agnieszka (Department of Neurology, Jagiellonian University Medical College) ; Sousa, Alessandro (Department of Neurology, University of Maryland School of Medicine) ; Stanne, Tara M. (University of Gothenburg) ; Strbian, Daniel (Department of Neurology, Helsinki University Central Hospital) ; Tatlisumak, Turgut (Department of Neurology, Sahlgrenska University Hospital) ; Thijs, Vincent (Florey Institute of Neuroscience and Mental Health, Department of Neurology Austin Health) ; Vagal, Achala (Department of Radiology, University of Cincinnati College of Medicine) ; Wasselius, Johan (Skåne University Hospital (Suècia)) ; Woo, Daniel (Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine) ; Wu, Ona (Massachusetts General Hospital) ; Zand, Ramin (Department of Neurology, Geisinger) ; Worrall, Bradford B. (Department of Neurology and Public Health Sciences, University of Virginia) ; Maguire, Jane M. (University of Technology Sydney) ; Lindgren, Arne (Department of Clinical Sciences Lund, Lund University) ; Jern, Christina (Sahlgrenska Academy at University of Gothenburg) ; Golland, Polina (Massachusetts Institute of Technology) ; Kuchcinski, Grégory (University of Lille) ; Rost, Natalia S. (Massachusetts General Hospital) ; Universitat Autònoma de Barcelona
Neuroimaging measurements of brain structural integrity are thought to be surrogates for brain health, but precise assessments require dedicated advanced image acquisitions. By means of quantitatively describing conventional images, radiomic analyses hold potential for evaluating brain health. [...]
2021 - 10.3389/fnins.2021.691244
Frontiers in Neuroscience, Vol. 15 (july 2021)  
5.
10 p, 678.7 KB Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke / Hong, Sungmin (Massachusetts General Hospital) ; Giese, Anne-Katrin (University Medical Center Hamburg-Eppendorf) ; Schirmer, Markus D. (University Hospital Bonn) ; Bonkhoff, Anna K. (Massachusetts General Hospital) ; Bretzner, Martin (Université du Lille) ; Rist, Pamela (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Dalca, Adrian V. (Department of Radiology, Massachusetts General Hospital) ; Regenhardt, Robert W. (Massachusetts General Hospital) ; Etherton, Mark R. (Massachusetts General Hospital) ; Donahue, Kathleen L. (Massachusetts General Hospital) ; Nardin, Marco (Harvard Medical School) ; Mocking, Steven J. T. (Massachusetts General Hospital) ; McIntosh, Elissa C. (Massachusetts General Hospital) ; Attia, John (University of Newcastle) ; Benavente, Oscar R. (University of British Columbia) ; Cole, John W. (University of Maryland. School of Medicine) ; Donatti, Amanda (University of Campinas) ; Griessenauer, Christoph J. (Research Institute of Neurointervention, Paracelsus Medical University) ; Heitsch, Laura (Washington University School of Medicine) ; Holmegaard, Lukas (University of Gothenburg) ; Jood, Katarina (University of Gothenburg) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Kittner, Steven J. (University of Maryland School of Medicine) ; Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ; Levi, Christopher R. (John Hunter Hospital) ; McDonough, Caitrin W. (University of Florida) ; Meschia, James F. (Mayo Clinic (Estats Units d'Amèrica)) ; Phuah, Chia-Ling (Department of Neurology, Washington University School of Medicine & Barnes-Jewish Hospital) ; Rolfs, Arndt (Centogene AG (Alemanya)) ; Ropele, Stefan (Department of Neurology, Medical University Graz) ; Rosand, Jonathan (Massachusetts General Hospital) ; Rundek, Tatjana (Department of Neurology, University of Miami) ; Sacco, Ralph L. (Department of Neurology , University of Miami) ; Schmidt, Reinhold (Department of Neurology, Medical University Graz) ; Enzinger, Christian (Department of Neurology, Medical University Graz) ; Sharma, Pankaj (St. Peter's and Ashford Hospitals) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Sousa, Alessandro (University of Campinas) ; Stanne, Tara M. (University of Gothenburg) ; Strbian, Daniel (University of Helsinki) ; Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ; Thijs, Vincent (Austin Health (Austràlia)) ; Vagal, Achala (University of Cincinnati College of Medicine) ; Wasselius, Johan (Skåne University Hospital (Suècia)) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Zand, Ramin (Geisinger (Estats Units d'Amèrica)) ; McArdle, Patrick F. (University of Maryland School of Medicine) ; Worrall, Bradford B. (University of Virginia) ; Wu, Ona (Massachusetts General Hospital) ; Jern, Christina (Department of University of Gothenburg) ; Lindgren, Arne G. (Lund University. Department of Clinical Sciences) ; Maguire, Jane (University of Technology Sydney) ; Tomppo, Liisa (University of Helsinki) ; Golland, Polina (Massachusetts Institute of Technology) ; Rost, Natalia S. (Massachusetts General Hospital) ; Universitat Autònoma de Barcelona
Objective: To personalize the prognostication of post-stroke outcome using MRI-detected cerebrovascular pathology, we sought to investigate the association between the excessive white matter hyperintensity (WMH) burden unaccounted for by the traditional stroke risk profile of individual patients and their long-term functional outcomes after a stroke. [...]
2021 - 10.3389/fneur.2021.700616
Frontiers in neurology, Vol. 12 (september 2021)  
6.
12 p, 4.9 MB Limits to reproduction and seed size-number trade-offs that shape forest dominance and future recovery / Qiu, Tong (Duke University. Nicholas School of the Environment) ; Andrus, Robert (University of Colorado Boulder. Department of Geography) ; Aravena Acuña, Marie-Claire (Universidad de Chile) ; Ascoli, Davide (Università degli studi di Torino. Dipartimento di Scienze Agrarie, Forestali e Alimentari) ; Bergeron, Yves (University of Quebec in Abitibi-Temiscamingue. Forest Research Institute) ; Berretti, Roberta (University of Torino. Department of Agriculture, Forest and Food Sciences) ; Berveiller, Daniel (Universite Paris-Saclay) ; Bogdziewicz, Michał (Adam Mickiewicz University. Department of Systematic Zoology) ; Boivin, Thomas (Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Bonal, Raul (Complutense University of Madrid. Department of Biodiversity, Ecology and Evolution) ; Bragg, Don C. (USDA Forest Service. Southern Research Station) ; Caignard, Thomas (Universite Bordeaux. Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Calama, Rafael (Centro de Investigacion Forestal. Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria) ; Camarero, Jesús Julio (Instituto Pirenaico de Ecología) ; Chang-Yang, Chia-Hao (National Sun Yat-sen University. Department of Biological Sciences) ; Cleavitt, Natalie L. (Cornell University. Natural Resources) ; Courbaud, Benoit (Universite Grenoble Alpes. Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Courbet, Francois (Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Curt, Thomas (Aix Marseille universite. Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Das, Adrian J. (USGS Western Ecological Research Center) ; Daskalakou, Evangelia (Institute of Mediterranean and Forest Ecosystems) ; Davi, Hendrik (Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Delpierre, Nicolas (Universite Paris-Saclay. Centre national de la recherche scientifique) ; Delzon, Sylvain (Universite Bordeaux. Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Dietze, Michael (Boston University. Earth and Environment) ; Calderon, Sergio Donoso (Universidad de Chile) ; Dormont, Laurent (Centre d'Ecologie Fonctionnelle et Evolutive) ; Espelta Morral, Josep Maria (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Fahey, Timothy J. (Cornell University) ; Farfan-Rios, William (Washington University in Saint Louis) ; Gehring, Catherine A. (Northern Arizona University. Department of Biological Sciences) ; Gilbert, Gregory S. (University of California. Department of Environmental Studies) ; Gratzer, Georg (Institute of Forest Ecology) ; Greenberg, Cathryn H. (Bent Creek Experimental Forest) ; Guo, Qinfeng (Eastern Forest Environmental Threat Assessment Center) ; Hacket-Pain, Andrew (University of Liverpool. Department of Geography and Planning) ; Hampe, Arndt (Universite Bordeaux, Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Han, Qingmin (Department of Plant Ecology Forestry and Forest Products Research Institute) ; Hille Ris Lambers, Janneke (ETH Zurich. Department of Environmental Systems Science) ; Hoshizaki, Kazuhiko (Akita Prefectural University. Department of Biological Environment) ; Ibanez, Ines (University of Michigan. School for Environment and Sustainability) ; Johnstone, J. F (University of Alaska. Institute of Arctic Biology) ; Journé, Valentin (Universite Grenoble Alpes. Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Kabeya, Daisuke (Forest Products Research Institute. Department of Plant Ecology Forestry) ; Kilner, Christopher L. (Duke University. Nicholas School of the Environment) ; Kitzberger, Thomas (Universidad Nacional del Comahue. Department of Ecology) ; Knops, Johannes M. H. (Xian Jiaotong-Liverpool University. Health and Environmental Sciences Department) ; Kobe, Richard K. (Michigan State University. Department of Plant Biology, Program in Ecology, Evolutionary Biology, and Behavior) ; Kunstler, Georges (Universite Grenoble Alpes. Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Lageard, Jonathan G. A. (Manchester Metropolitan University. Department of Natural Sciences) ; LaMontagne, Jalene M. (DePaul University. Department of Biological Sciences) ; Ledwon, Mateusz (Polish Academy of Sciences. Institute of Systematics and Evolution of Animals) ; Lefevre, Francois (Institut National de Recherche pour Agriculture, Alimentation et Environnement) ; Leininger, Theodor (USDA, Forest Service, Southern Research Station) ; Limousin, Jean-Marc (Université Montpellier) ; Lutz, James A. (Utah State University. Department of Wildland Resources, and the Ecology Center) ; Macias, Diana (University of New Mexico. Department of Biology) ; McIntire, Eliot J. B. (Pacific Forestry Centre) ; Moore, Christopher M. (Colby College. Department of Biology) ; Moran, Emily (School of Natural Sciences) ; Motta, Renzo (University of Torino. Department of Agriculture, Forest and Food Sciences) ; Myers, Jonathan A. (Washington University in St. Louis. Department of Biology) ; Nagel, Thomas A. (University of Ljubljana. Department of forestry and renewable forest resources) ; Noguchi, Kyotaro (Forestry and Forest Products Research Institute. Tohoku Research Center) ; Ourcival, Jean-Marc (Université Montpellier) ; Parmenter, Robert (Valles Caldera National Preserve, National Park Service) ; Pearse, Ian S. (Fort Collins Science Center) ; Perez-Ramos, Ignacio M. (Consejo Superior de Investigaciones Cientificas) ; Piechnik, Lukasz (Polish Academy of Sciences. W Szafer Institute of Botany) ; Poulsen, John (Duke University. Nicholas School of the Environment) ; Poulton-Kamakura, Renata (Duke University. Nicholas School of the Environment) ; Redmond, Miranda D. (Colorado State University. Department of Forest and Rangeland Stewardship) ; Reid, Chantal D. (Duke University. Nicholas School of the Environment) ; Rodman, Kyle C. (University of Wisconsin-Madison. Department of Forest and Wildlife Ecology) ; Rodriguez-Sanchez, Francisco (Universidad de Sevilla. Departamento de Biología Vegetal y Ecología) ; Sanguinetti, Javier D. (Parque Nacional Lanin Elordi y Perito Moreno) ; Scher, C. Lane (Duke University. Nicholas School of the Environment) ; Schlesinger, William H. (Duke University. Nicholas School of the Environment) ; Schmidt Van Marle, Harald (Universidad de Chile) ; Seget, Barbara (Polish Academy of Sciences. W Szafer Institute of Botany) ; Sharma, Shubhi (Duke University. Nicholas School of the Environment) ; Silman, Miles (Wake Forest University. Department of Biology) ; Steele, Michael A. (Wilkes University. Department of Biology) ; Stephenson, Nathan L. (Western Ecological Research Center) ; Straub, Jacob N. (State University of New York-Brockport. Department of Environmental Science and Ecology) ; Sun, I-Fang (National Dong Hwa University. College of Environmental Studies) ; Sutton, Samantha (Duke University. Nicholas School of the Environment) ; Swenson, Jennifer J. (Duke University. Nicholas School of the Environment) ; Swift, Margaret (Duke University. Nicholas School of the Environment) ; Thomas, Peter A. (Keele University. School of Life Sciences) ; Uriarte, Maria (Columbia University. Department of Ecology, Evolution and Environmental Biology) ; Vacchiano, Giorgio (University of Milan. Department of Agricultural and Environmental Sciences) ; Veblen, Thomas T. (University of Colorado Boulder. Department of Geography) ; Whipple, Amy V. (Northern Arizona University. Department of Biological Sciences) ; Whitham, Thomas G. (Northern Arizona University. Department of Biological Sciences) ; Wion, Andreas P. (Colorado State University. Department of Forest and Rangeland Stewardship) ; Wright, Boyd (University of New England. School of Environmental and Rural Science) ; Wright, Stuart Joseph (Smithsonian Tropical Research Institute) ; Zhu, Kai (University of California. Department of Environmental Studies) ; Zimmerman, Jess K. (University of Puerto Rico. Department of Environmental Sciences) ; Zlotin, Roman (Geography Department and Russian and East European Institute) ; Zywiec, Magdalena (Polish Academy of Sciences. W Szafer Institute of Botany) ; Clark, James S. (Universite Grenoble Alpes. Institut National de Recherche pour Agriculture, Alimentation et Environnement)
The relationships that control seed production in trees are fundamental to understanding the evolution of forest species and their capacity to recover from increasing losses to drought, fire, and harvest. [...]
2022 - 10.1038/s41467-022-30037-9
Nature communications, Vol. 13 (May 2022) , art. 2381  
7.
12 p, 1.9 MB Sex-specific lesion pattern of functional outcomes after stroke / Bonkhoff, Anna K. (J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Harvard Medical School) ; Bretzner, Martin (Univ. Lille) ; Hong, Sungmin (Massachusetts General Hospital (Boston)) ; Schirmer, Markus D. (University Hospital Bonn (Bonn, Alemanya)) ; Cohen, Alexander (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ; Regenhardt, Robert W. (Massachusetts General Hospital (Boston)) ; Donahue, Kathleen L. (Massachusetts General Hospital (Boston)) ; Nardin, Marco J. (Massachusetts General Hospital (Boston)) ; Dalca, Adrian Vasile (Massachusetts General Hospital (Boston)) ; Giese, Anne-Katrin (University Medical Center Hamburg-Eppendorf) ; Etherton, Mark R. (Massachusetts General Hospital (Boston)) ; Hancock, Brandon L. (Massachusetts General Hospital (Boston)) ; Mocking, Steven J. T. (Massachusetts General Hospital (Boston)) ; McIntosh, Elissa C. (Massachusetts General Hospital (Boston)) ; Attia, John (University of Newcastle) ; Benavente, Oscar R. (University of British Columbia) ; Bevan, Stephen (University of Lincoln) ; Cole, John W. (University of Maryland School of Medicine) ; Donatti, Amanda (University of Campinas) ; Griessenauer, Christoph J. (Paracelsus Medical University) ; Heitsch, Laura (Washington University School) ; Holmegaard, Lukas (Sahlgrenska University Hospital (Suècia)) ; Jood, Katarina (Sahlgrenska University Hospital (Suècia)) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Kittner, Steven J. (University of Maryland) ; Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ; Levi, Christopher R. (John Hunter Hospital) ; McDonough, Caitrin W. (University of Florida) ; Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ; Phuah, Chia-Ling (Washington University School of Medicine) ; Rolfs, Arndt (Centogene AG) ; Ropele, Stefan (Medical University Graz) ; Rosand, Jonathan (Massachusetts General Hospital (Boston)) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rundek, Tatjana (University of Miami) ; Sacco, Ralph L. (University of Miami. Miller School of Medicine) ; Schmidt, Reinhold (Medical University Graz) ; Sharma, Pankaj (St Peter's and Ashford Hospital) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Söderholm, Martin (Skåne University Hospital (Suècia)) ; Sousa, Alessandro (University of Campinas) ; Stanne, Tara M. (University of Gothenburg) ; Strbian, Daniel (Helsinki University Hospital) ; Tatlisumak, Turgut (Sahlgrenska Academy at University of Gothenburg) ; Thijs, Vincent (Austin Health) ; Vagal, Achala (University of Cincinnati College of Medicine) ; Wasselius, Johan (Skåne University Hospital (Suècia)) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Zand, Ramin (Department of Neurology, Geisinger) ; McArdle, Patrick F. (University of Maryland School of Medicine) ; Worrall, Bradford B. (University of Virginia) ; Jern, Christina (Sahlgrenska University Hospital (Suècia)) ; Lindgren, Arne G. (Lund University) ; Maguire, Jane (University of Technology Sydney) ; Fox, Michael D. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Bzdok, Danilo (Mila-Quebec Artificial Intelligence Institute) ; Wu, Ona (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ; Rost, Natalia S. (Massachusetts General Hospital (Boston)) ; Universitat Autònoma de Barcelona
Stroke represents a considerable burden of disease for both men and women. However, a growing body of literature suggests clinically relevant sex differences in the underlying causes, presentations and outcomes of acute ischaemic stroke. [...]
2022 - 10.1093/braincomms/fcac020
Brain Communications, Vol. 4 (february 2022)  
8.
14 p, 3.0 MB Outcome after acute ischemic stroke is linked to sex-specific lesion patterns / Bonkhoff, Anna K. (Massachusetts General Hospital (Boston)) ; Schirmer, Markus D. (University Hospital Bonn (Bonn, Alemanya)) ; Bretzner, Martin (Univ. Lille) ; Hong, Sungmin (Massachusetts General Hospital (Boston)) ; Regenhardt, Robert W. (Massachusetts General Hospital (Boston)) ; Brudfors, Mikael (School of Biomedical Engineering & Imaging Sciences) ; Donahue, Kathleen L. (Massachusetts General Hospital (Boston)) ; Nardin, Marco J. (Massachusetts General Hospital (Boston)) ; Dalca, Adrian Vasile (Massachusetts General Hospital (Boston)) ; Giese, Anne-Katrin (University Medical Center Hamburg-Eppendorf) ; Etherton, Mark R. (Massachusetts General Hospital (Boston)) ; Hancock, Brandon L. (Massachusetts General Hospital (Boston)) ; Mocking, Steven J. T. (Massachusetts General Hospital (Boston)) ; McIntosh, Elissa C. (Massachusetts General Hospital (Boston)) ; Attia, John (School of Medicine and Public Health) ; Benavente, Oscar R. (University of British Columbia) ; Bevan, Stephen (University of Lincoln) ; Cole, John W. (University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System) ; Donatti, Amanda (Brazilian Institute of Neuroscience and Neurotechnology (BRAINN)) ; Griessenauer, Christoph J. (Research Institute of Neurointervention) ; Heitsch, Laura (Washington University School of Medicine & Barnes-Jewish Hospital) ; Holmegaard, Lukas (Sahlgrenska University Hospital (Suècia)) ; Jood, Katarina (Sahlgrenska University Hospital (Suècia)) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Kittner, Steven J. (University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System) ; Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ; Levi, Christopher R. (John Hunter Hospital) ; McDonough, Caitrin W. (University of Florida) ; Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ; Phuah, Chia-Ling (Washington University School of Medicine) ; Rolfs, Arndt (Centogene AG) ; Ropele, Stefan (Medical University Graz) ; Rosand, Jonathan (Massachusetts General Hospital (Boston)) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rundek, Tatjana (University of Miami) ; Sacco, Ralph L. (University of Miami) ; Schmidt, Reinhold (Medical University Graz) ; Sharma, Pankaj (St Peter's and Ashford Hospitals) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Söderholm, Martin (Skåne University Hospital (Suècia)) ; Sousa, Alessandro (Brazilian Institute of Neuroscience and Neurotechnology (BRAINN)) ; Stanne, Tara M. (the Sahlgrenska Academy at University of Gothenburg) ; Strbian, Daniel (Helsinki University Hospital (Finlàndia)) ; Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ; Thijs, Vincent (Austin Health) ; Vagal, Achala (University of Cincinnati College of Medicine) ; Wasselius, Johan (Skåne University Hospital (Suècia)) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Zand, Ramin (Geisinger) ; McArdle, Patrick F. (University of Maryland School of Medicine) ; Worrall, Bradford B. (University of Virginia) ; Jern, Christina (Sahlgrenska University Hospital (Suècia)) ; Lindgren, Arne G. (Lund University) ; Maguire, Jane (University of Technology Sydney) ; Bzdok, Danilo (Mila - Quebec Artificial Intelligence Institute) ; Wu, Ona (Massachusetts General Hospital (Boston)) ; Rost, Natalia S. (Massachusetts General Hospital (Boston)) ; Universitat Autònoma de Barcelona
Acute ischemic stroke affects men and women differently. In particular, women are often reported to experience higher acute stroke severity than men. We derived a low-dimensional representation of anatomical stroke lesions and designed a Bayesian hierarchical modeling framework tailored to estimate possible sex differences in lesion patterns linked to acute stroke severity (National Institute of Health Stroke Scale). [...]
2021 - 10.1038/s41467-021-23492-3
Nature communications, Vol. 12 (june 2021)  
9.
22 p, 1.6 MB Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus / Lawrenson, Kate (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Kar, Siddhartha (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; McCue, Karen (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Kuchenbaeker, Karoline (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Michailidou, Kyriaki (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Tyrer, Jonathan (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Beesley, Jonathan (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Ramus, Susan J. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Li, Qiyuan (Department of Medical Oncology, The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute) ; Delgado, Melissa K. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Lee, Janet M. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Aittomäki, Kristiina (Helsinki University Hospital (Finlàndia)) ; Andrulis, Irene L. (Department of Molecular Genetics, University of Toronto) ; Anton-Culver, Hoda (Department of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine) ; Arndt, Volker (Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)) ; Arun, Banu K. (University of Texas MD Anderson Cancer Center) ; Arver, Brita (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Bandera, Elisa V. (Cancer Prevention and Control, Rutgers Cancer Institute of New Jersey) ; Barile, Monica (Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia) ; Barkardottir, Rosa B. (Department of Pathology, Landspitali University Hospital and BMC (Biomedical Centre), Faculty of Medicine, University of Iceland) ; Barrowdale, Daniel (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Beckmann, Matthias W. (University Hospital Erlangen, Department of Gynecology and Obstetrics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN) ; Benitez, Javier (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Berchuck, Andrew (Department of Obstetrics and Gynecology, Duke University Medical Center) ; Bisogna, Maria (Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center) ; Bjorge, Line (Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen) ; Blomqvist, Carl (Helsinki University Hospital (Finlàndia)) ; Blot, William (International Epidemiology Institute) ; Bogdanova, Natalia (Gynaecology Research Unit, Hannover Medical School) ; Bojesen, Anders (Department of Clinical Genetics, Vejle Hospital) ; Bojesen, Stig E. (Copenhagen University Hospital) ; Bolla, Manjeet K. (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Bonanni, Bernardo (Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia) ; Børresen-Dale, Anne-Lise (K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo) ; Brauch, Hiltrud (German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ)) ; Brennan, Paul (International Agency for Research on Cancer) ; Brenner, Hermann (Division of Preventive Oncology, German Cancer Research Center (DKFZ)) ; Bruinsma, Fiona (Cancer Epidemiology Centre (Melbourne, Austràlia)) ; Brunet, Joan (Institut d'Investigació Biomèdica de Girona) ; Buhari, Shaik Ahmad (Department of Surgery, National University Health System) ; Burwinkel, Barbara (Department of Obstetrics and Gynecology, University of Heidelberg) ; Butzow, Ralf (Department of Pathology, Helsinki University Central Hospital) ; Buys, Saundra (Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine) ; Cai, Qiuyin (Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Campbell, Ian (Cancer Genetics Laboratory, Peter MacCallum Cancer Centre) ; Canniotto, Rikki (Cancer Pathology & Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute) ; Chang-Claude, Jenny (University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf) ; Chiquette, Jocelyne (Unité de recherche en santé des populations, Centre des maladies du sein Deschênes-Fabia, Centre de recherche FRSQ du Centre hospitalier affilié universitaire de Québec) ; Choi, Ji-Yeob (Department of Biomedical Sciences, Seoul National University College of Medicine) ; Claes, Kathleen (Center for Medical Genetics, Ghent University) ; Cook, Linda S. (Division of Epidemiology and Biostatistics, Department of Internal Medicine, University of New Mexico) ; Cox, Angela (Sheffield Cancer Research, Department of Oncology, University of Sheffield) ; Cramer, Daniel W. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Cross, Simon S. (Academic Unit of Pathology, Department of Neuroscience, University of Sheffield) ; Cybulski, Cezary (Department of Genetics and Pathology, Pomeranian Medical University) ; Czene, Kamila (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Daly, Mary B. (Department of Clinical Genetics, Fox Chase Cancer Center) ; Damiola, Francesca (INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon) ; Dansonka-Mieszkowska, Agnieszka (Department of Pathology and Laboratory Diagnostics the Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology) ; Darabi, Hatef (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Dennis, Joe (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Devilee, Peter (Department of Human Genetics, Leiden University Medical Center) ; Diez, Orland (Vall d'Hebron Institut d'Oncologia) ; Doherty, Jennifer A. (Department of Community and Family Medicine, Section of Biostatistics & Epidemiology, The Geisel School of Medicine at Dartmouth) ; Domchek, Susan M. (Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania) ; Dorfling, Cecilia M. (Department of Genetics, University of Pretoria) ; Dörk, Thilo (Gynaecology Research Unit, Hannover Medical School) ; Dumont, Martine (Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University) ; Ehrencrona, Hans (Department of Clinical Genetics, Lund University Hospital) ; Ejlertsen, Bent (Copenhagen University Hospital Rigshospitalet) ; Ellis, Steve (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Engel, Christoph (Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig) ; Lee, Eunjung (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Evans, Gareth (Genomic Medicine, Manchester Academic Health Sciences Centre, Institute of Human Development, Manchester University, Central Manchester University Hospitals NHS Foundation Trust) ; Fasching, Peter A. (University of California at Los Angeles, David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology) ; Feliubadalo, Lidia (Institut d'Investigació Biomèdica de Bellvitge) ; Figueroa, Jonine (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Flesch-Janys, Dieter (Department of Cancer Epidemiology, Clinical Cancer Registry, University Medical Center Hamburg-Eppendorf) ; Fletcher, Olivia (Division of Breast Cancer Research, The Institute of Cancer Research) ; Flyger, Henrik (Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital) ; Foretova, Lenka (Masaryk Memorial Cancer Institute and Medical Faculty MU) ; Fostira, Florentia (Molecular Diagnostics Laboratory, (INRASTES) Institute of Nuclear and Radiological Sciences and Technology, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ; Foulkes, William D. (Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal) ; Fridley, Brooke L. (Biostatistics and Informatics Shared Resource, University of Kansas Medical Center) ; Friedman, Eitan (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ; Frost, Debra (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Gambino, Gaetana (University Hospital of Pisa (Pisa, Itàlia)) ; Ganz, Patricia A. (UCLA Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Center) ; Garber, Judy (Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute) ; García-Closas, Montserrat (Division of Genetics and Epidemiology, The Institute of Cancer Research) ; Gentry-Maharaj, Aleksandra (Women's Cancer, UCL EGA Institute for Women's Health) ; Ghoussaini, Maya (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Giles, Graham G. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Glasspool, Rosalind (Cancer Research UK Clinical Trials Unit, The Beatson West of Scotland Cancer Centre) ; Godwin, Andrew K. (Department of Pathology and Laboratory Medicine, University of Kansas Medical Center) ; Goldberg, Mark S. (Department of Medicine, McGill University) ; Goldgar, David E. (Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine) ; González-Neira, Anna (Centro Nacional de Investigaciones Oncológicas) ; Goode, Ellen L. (Department of Health Sciences Research, Mayo Clinic) ; Goodman, Marc T. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Greene, Mark H. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ; Gronwald, Jacek (Department of Genetics and Pathology, Pomeranian Medical University) ; Guénel, Pascal (University Paris-Sud) ; Haiman, Christopher A. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Hall, Per (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Hallberg, Emily (Department of Health Sciences Research, Mayo Clinic) ; Hamann, Ute (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ; Hansen, Thomas V. O. (Copenhagen University Hospital Rigshospitalet) ; Harrington, Patricia A. (Department of Oncology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory) ; Hartman, Mikael (Saw Swee Hock School of Public Health, National University of Singapore) ; Hassan, Norhashimah (Cancer Research Initiatives Foundation, Subang Jaya) ; Healey, Sue (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Heitz, Florian (Department of Gynecology and Gynecologic Oncology, Dr Horst Schmidt Kliniken Wiesbaden) ; Herzog, Josef (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ; Høgdall, Estrid (Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center) ; Høgdall, Claus K. (Copenhagen University Hospital Rigshospitalet) ; Hogervorst, Frans B. L. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Hollestelle, Antoinette (Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute) ; Hopper, John L. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Hulick, Peter J. (Center for Medical Genetics, NorthShore University Health System) ; Huzarski, Tomasz (Department of Genetics and Pathology, Pomeranian Medical University) ; Imyanitov, Evgeny N. (N.N. Petrov Institute of Oncology) ; Isaacs, Claudine (Lombardi Comprehensive Cancer Center, Georgetown University) ; Ito, Hidemi (Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute) ; Jakubowska, Anna (Department of Genetics and Pathology, Pomeranian Medical University) ; Janavicius, Ramunas (State Research Institute Centre for Innovative Medicine) ; Jensen, Allan (Copenhagen University Hospital Rigshospitalet) ; John, Esther M. (Department of Epidemiology, Cancer Prevention Institute of California) ; Johnson, Nichola (Division of Breast Cancer Research, The Institute of Cancer Research) ; Kabisch, Maria (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ; Kang, Daehee (Department of Preventive Medicine, Seoul National University College of Medicine) ; Kapuscinski, Miroslav (Centre for Epidemiology and Biostatistics, University of Melbourne) ; Karlan, Beth Y. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Khan, Sofia (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ; Kiemeney, Lambertus A. (Radboud University Medical Centre, Radboud Institute for Health Sciences) ; Kjaer, Susanne Kruger (Copenhagen University Hospital Rigshospitalet) ; Knight, Julia A. (Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto) ; Konstantopoulou, Irene (Molecular Diagnostics Laboratory, (INRASTES) Institute of Nuclear and Radiological Sciences and Technology, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ; Kosma, Veli-Matti (Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ; Kristensen, Vessela (Oslo University Hospital (Oslo, Noruega)) ; Kupryjanczyk, Jolanta (Department of Pathology and Laboratory Diagnostics the Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology) ; Kwong, Ava (Department of Surgery, The University of Hong Kong) ; De la Hoya, Miguel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Laitman, Yael (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ; Lambrechts, Diether (Laboratory for Translational Genetics, Department of Oncology, University of Leuven) ; Le, Nhu (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; De Leeneer, Kim (Center for Medical Genetics, Ghent University) ; Lester, Jenny (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Levine, Douglas A. (Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center) ; Li, Jingmei (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Lindblom, Annika (Karolinska Institutet (Estocolm, Suècia). Department of Molecular Medicine and Surgery) ; Long, Jirong (Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Lophatananon, Artitaya (Division of Health Sciences, Warwick Medical School, Warwick University) ; Loud, Jennifer T. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ; Lu, Karen (Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center) ; Lubinski, Jan (Department of Genetics and Pathology, Pomeranian Medical University) ; Mannermaa, Arto (Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ; Manoukian, Siranoush (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT)) ; Le Marchand, Loic (University of Hawaii Cancer Center) ; Margolin, Sara (Department of Oncology - Pathology, Karolinska Institutet) ; Marme, Frederik (National Center for Tumour Diseases, University of Heidelberg) ; Massuger, Leon F. A. G. (Radboud University Medical Centre. Department of Gynaecology) ; Matsuo, Keitaro (Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences) ; Mazoyer, Sylvie (INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon) ; McGuffog, Lesley (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; McLean, Catriona (Anatomical Pathology, The Alfred Hospital) ; McNeish, Iain (Institute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Beatson Institute for Cancer Research) ; Meindl, Alfons (Technische Universität München) ; Menon, Usha (Women's Cancer, UCL EGA Institute for Women's Health) ; Mensenkamp, Arjen R. (Department of Human Genetics, Radboud University Medical Centre) ; Milne, Roger L. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Montagna, Marco (Immunology and Molecular Oncology Unit, Instituto Oncologico Veneto IOV, IRCCS) ; Moysich, Kirsten B. (Department of Cancer Prevention and Control, Roswell Park Cancer Institute) ; Muir, Kenneth (Institute of Population Health, University of Manchester) ; Mulligan, Anna Marie (Department of Laboratory Medicine and Pathobiology, University of Toronto) ; Nathanson, Katherine L. (Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania) ; Ness, Roberta B. (The University of Texas School of Public Health) ; Neuhausen, Susan L. (Department of Population Sciences, Beckman Research Institute of City of Hope) ; Nevanlinna, Heli (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ; Nord, Silje (K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo) ; Nussbaum, Robert L. (Department of Medicine and Genetics, University of California) ; Odunsi, Kunle (Department of Gynecological Oncology, Roswell Park Cancer Institute) ; Offit, Kenneth (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ; Olah, Edith (Department of Molecular Genetics, National Institute of Oncology) ; Olopade, Olufunmilayo I. (Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center) ; Olson, Janet E. (Department of Health Sciences Research, Mayo Clinic) ; Olswold, Curtis (Department of Health Sciences Research, Mayo Clinic) ; O'Malley, David (The Ohio State University and the James Cancer Center) ; Orlow, Irene (Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center) ; Orr, Nick (Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research) ; Osorio, Ana (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Park, Sue Kyung (Department of Surgery, Seoul National University College of Medicine) ; Pearce, Celeste L. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Pejovic, Tanja (Knight Cancer Institute, Oregon Health and Science University) ; Peterlongo, Paolo (IFOM, The FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology) ; Pfeiler, Georg (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ; Phelan, Catherine M. (Department of Cancer Epidemiology, Moffitt Cancer Center) ; Poole, Elizabeth M. (Department of Epidemiology, Harvard TH Chan School of Public Health) ; Pylkäs, Katri (Laboratory of Cancer Genetics and Tumour Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu) ; Radice, Paolo (Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT)) ; Rantala, Johanna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Rashid, Muhammad Usman (Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC)) ; Rennert, Gad (Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine) ; Rhenius, Valerie (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Rhiem, Kerstin (University Hospital of Cologne (Colònia, Alemanya). Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO)) ; Risch, Harvey A. (Department of Chronic Disease Epidemiology, Yale School of Public Health) ; Rodriguez, Gus (Division of Gynecologic Oncology, NorthShore University HealthSystem) ; Rossing, Mary Anne (Department of Epidemiology, University of Washington) ; Rudolph, Anja (Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)) ; Salvesen, Helga B. (Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen) ; Sangrajrang, Suleeporn (National Cancer Institute) ; Sawyer, Elinor J. (King's College London) ; Schildkraut, Joellen M. (Cancer Control and Population Sciences, Duke Cancer Institute) ; Schmidt, Marjanka K. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ; Schmutzler, Rita K. (Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne) ; Sellers, Thomas A. (Department of Cancer Epidemiology, Moffitt Cancer Center) ; Seynaeve, Caroline (Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute) ; Shah, Mitul (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Shen, Chen-Yang (School of Public Health, China Medical University) ; Shu, Xiao-Ou (Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Sieh, Weiva (Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine) ; Singer, Christian F. (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ; Sinilnikova, Olga M. (INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon) ; Slager, Susan (Department of Health Sciences Research, Mayo Clinic) ; Song, Honglin (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Soucy, Penny (Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University) ; Southey, Melissa C. (Department of Pathology, University of Melbourne) ; Stenmark-Askmalm, Marie (Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University) ; Stoppa-Lyonnet, Dominique (Université Paris Descartes) ; Sutter, Christian (Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg) ; Swerdlow, Anthony (Division of Genetics and Epidemiology, The Institute of Cancer Research) ; Tchatchou, Sandrine (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ; Teixeira, Manuel R. (Biomedical Sciences Institute (ICBAS), Porto University) ; Teo, Soo H. (Cancer Research Initiatives Foundation, Subang Jaya) ; Terry, Kathryn L. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Terry, Mary Beth (Department of Epidemiology, Mailman School of Public Health, Columbia University) ; Thomassen, Mads (Odense University Hospital (Dinamarca)) ; Tibiletti, Maria Grazia (UO Anatomia Patologica, Ospedale di Circolo-Università dell'Insubria) ; Tihomirova, Laima (Latvian Biomedical Research and Study Centre) ; Tognazzo, Silvia (Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico)) ; Toland, Amanda Ewart (Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University) ; Tomlinson, Ian (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Torres, Diana (Institute of Human Genetics, Pontificia Universidad Javeriana, Cra. 7 #40-62) ; Truong, Thérèse (University Paris-Sud) ; Tseng, Chiu-chen (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Tung, Nadine (Department of Medical Oncology, Beth Israel Deaconess Medical Center) ; Tworoger, Shelley S. (Department of Epidemiology, Harvard TH Chan School of Public Health) ; Vachon, Celine (Department of Health Sciences Research, Mayo Clinic) ; van den Ouweland, Ans M. W. (Department of Clinical Genetics, Erasmus University Medical Center) ; van Doorn, Helena C. (Department of Gynecology, Family Cancer Clinic, Erasmus MC Cancer Institute) ; van Rensburg, Elizabeth J. (Department of Genetics, University of Pretoria) ; Van't Veer, Laura J. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ; Vanderstichele, Adriaan (University Hospitals Leuven (Bèlgica)) ; Vergote, Ignace (University Hospitals Leuven (Bèlgica)) ; Vijai, Joseph (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ; Wang, Qin (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Wang-Gohrke, Shan (University Hospital Ulm, 89069 Ulm) ; Weitzel, Jeffrey N. (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ; Wentzensen, Nicolas (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Whittemore, Alice S. (Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine) ; Wildiers, Hans (University Hospitals Leuven (Bèlgica)) ; Winqvist, Robert (Laboratory of Cancer Genetics and Tumour Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu) ; Wu, Anna H. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Yannoukakos, Drakoulis (Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research 'Demokritos') ; Yoon, Sook-Yee (University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya) ; Yu, Jyh-Cherng (Department of Surgery, Tri-Service General Hospital, National Defense Medical Center) ; Zheng, Wei (Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Zheng, Ying (Shanghai Center for Disease Control and Prevention) ; Khanna, Kum Kum (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Simard, Jacques (Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University) ; Monteiro, Alvaro N. (Cancer Epidemiology Program, Division of Population Sciences, H. Lee Moffitt Cancer Center & Research Institute) ; French, Juliet D. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Couch, Fergus J. (Department of Laboratory Medicine and Pathology, Mayo Clinic) ; Freedman, Matthew L. (Department of Medical Oncology, The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute) ; Easton, Douglas F. (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Dunning, Alison M. (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Pharoah, Paul D. (Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Edwards, Stacey L. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Chenevix-Trench, Georgia (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Antoniou, Antonis C. (Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge) ; Gayther, Simon A. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Universitat Autònoma de Barcelona
A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P =9. [...]
2016 - 10.1038/ncomms12675
Nature communications, Vol. 7 (09 2016)  
10.
13 p, 1009.7 KB Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer / Couch, Fergus J. (Mayo Clinic) ; Kuchenbaecker, Karoline B. (University of Cambridge) ; Michailidou, Kyriaki (University of Cambridge) ; Mendoza-Fandino, Gustavo A. (H. Lee Moffitt Cancer Center and Research Institute) ; Nord, Silje (Oslo University Hospital (Oslo, Noruega)) ; Lilyquist, Janna (Mayo Clinic) ; Olswold, Curtis (Mayo Clinic) ; Hallberg, Emily (Mayo Clinic) ; Agata, Simona (Istituto Oncologico Veneto IOV-IRCCS) ; Ahsan, Habibul (The University of Chicago) ; Aittomäki, Kristiina (Helsinki University Central Hospital) ; Ambrosone, Christine B (Roswell Park Cancer Institute) ; Andrulis, Irene L. (University of Toronto) ; Anton-Culver, Hoda (University of California Irvine) ; Arndt, Volker (German Cancer Research Center) ; Arun, Banu K. (University of Texas MD Anderson Cancer Center) ; Arver, Brita (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Barile, Monica (Istituto Europeo di Oncologia) ; Barkardottir, Rosa B. (Landspitali University Hospital (Islàndia)) ; Barrowdale, Daniel (University of Cambridge) ; Beckmann, Lars (Institute for Quality and Efficiency in Health Care) ; Beckmann, Matthias W. (University Breast Center Franconia) ; Benitez, Javier (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Blank, Stephanie V. (New York University School of Medicine) ; Blomqvist, Carl (University of Helsinki and Helsinki University Central Hospital) ; Bogdanova, Natalia V. (Hannover Medical School) ; Bojesen, Stig E. (Copenhagen University Hospital) ; Bolla, Manjeet K. (University of Cambridge) ; Bonanni, Bernardo (Istituto Europeo di Oncologia) ; Brauch, Hiltrud (University of Tübingen) ; Brenner, Hermann (German Cancer Research Center and National Center for Tumor Diseases) ; Burwinkel, Barbara (University of Heidelberg) ; Buys, Saundra (University of Utah School of Medicine) ; Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Caligo, Maria (University Hospital of Pisa (Pisa, Itàlia)) ; Canzian, Federico (German Cancer Research Center) ; Carpenter, Jane (University of Sydney) ; Chang-Claude, Jenny (German Cancer Research Center) ; Chanock, Stephen (Centro Nacional de Investigaciones Oncológicas) ; Chung, Wendy (Columbia University) ; Claes, Kathleen (Ghent University) ; Cox, Angela (University of Sheffield) ; Cross, Simon S. (University of Sheffield) ; Cunningham, Julie M. (Mayo Clinic) ; Czene, Kamila (Karolinska Institutet (Estocolm, Suècia)) ; Daly, Mary B. (Fox Chase Cancer Center) ; Damiola, Francesca (Université Lyon) ; Darabi, Hatef (Karolinska Institutet (Estocolm, Suècia)) ; De la Hoya, Miguel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Devilee, Peter (Leiden University Medical Center) ; Diez, Orland (Vall d'Hebron Institut d'Oncologia) ; Ding, Yuan C. (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica)) ; Dolcetti, Riccardo (CRO Aviano National Cancer Institute) ; Domchek, Susan M. (University of Pennsylvania) ; Dorfling, Cecilia M. (University of Pretoria) ; dos-Santos-Silva, Isabel (London School of Hygiene and Tropical Medicine) ; Dumont, Martine (Laval University) ; Dunning, Alison M. (University of Cambridge) ; Eccles, Diana M. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ; Ehrencrona, Hans (Lund University Hospital) ; Ekici, Arif B. (Comprehensive Cancer Center -EMN) ; Eliassen, Heather (Harvard School of Public Health) ; Ellis, Steve (University of Cambridge) ; Fasching, Peter A. (University Breast Center Franconia) ; Figueroa, Jonine (National Cancer Institute) ; Flesch-Janys, Dieter (University Clinic Hamburg-Eppendorf) ; Försti, Asta (Lund University) ; Fostira, Florentia (Memokritos', Aghia Paraskevi Attikis) ; Foulkes, William D. (McGill University) ; Friebel, Tara (University of) ; Friedman, Eitan (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ; Frost, Debra (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Gabrielson, Marike (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Gammon, Marilie D. (Department of Epidemiology, University of) ; Ganz, Patricia A. (UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center) ; Gapstur, Susan M. (Epidemiology Research Program, American Cancer Society) ; Garber, Judy (Cancer Risk and Prevention Clinic, Dana Farber Cancer Institute) ; Gaudet, Mia M. (Epidemiology Research Program, American Cancer Society) ; Gayther, Simon A. (Department of Biomedical Sciences, Cedars Sinai Medical Center) ; Gerdes, Anne-Marie (Copenhagen University Hospital Rigshospitalet) ; Ghoussaini, Maya (University of Cambridge) ; Giles, Graham G. (Cancer Council Victoria) ; Glendon, Gord (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ; Godwin, Andrew K. (University of Kansas Medical Center) ; Goldberg, Mark S. (Royal Victoria Hospital) ; Goldgar, David E. (University of Utah School of Medicine) ; González-Neira, Anna (Centro Nacional de Investigaciones Oncológicas) ; Greene, Mark H. (Clinical Genetics Branch) ; Gronwald, Jacek (Pomeranian Medical University) ; Guénel, Pascal (Inserm (National Institute of Health and Medical Research)) ; Gunter, Marc (Imperial College London) ; Haeberle, Lothar (University Breast Center Franconia) ; Haiman, Christopher A. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Hamann, Ute (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ; Hansen, Thomas V. O. (Copenhagen University Hospital Rigshospitalet) ; Hart, Steven (Department of Health Sciences Research, Mayo Clinic) ; Healey, Sue (Department of Genetics, QIMR Berghofer Medical Research Institute) ; Heikkinen, Tuomas (Helsinki University Central Hospital) ; Henderson, Brian E. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Herzog, Josef (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ; Hogervorst, Frans B. L. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Hollestelle, Antoinette (Department of Medical Oncology, Erasmus MC Cancer Institute) ; Hooning, Maartje J. (Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center) ; Hoover, Robert (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Hopper, John L. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Humphreys, Keith (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Hunter, David J. (Program in Molecular and Genetic Epidemiology, Harvard School of Public Health) ; Huzarski, Tomasz (Department of Genetics and Pathology, Pomeranian Medical University) ; Imyanitov, Evgeny N. (N.N. Petrov Institute of Oncology) ; Isaacs, Claudine (Lombardi Comprehensive Cancer Center, Georgetown University) ; Jakubowska, Anna (Department of Genetics and Pathology, Pomeranian Medical University) ; James, Paul (Department of Oncology, The University of Melbourne) ; Janavicius, Ramunas (State Research Institute Centre for Innovative Medicine) ; Jensen, Uffe Birk (Aarhus University Hospital (Aarhus, Dinamarca)) ; John, Esther M. (Department of Epidemiology, Cancer Prevention Institute of California) ; Jones, Michael (Division of Genetics and Epidemiology, Institute of Cancer Research) ; Kabisch, Maria (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ; Kar, Siddhartha (Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge) ; Karlan, Beth Y. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Khan, Sofia (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ; Khaw, Kay-Tee (Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory) ; Kibriya, Muhammad G. (Department of Health Studies, The University of Chicago) ; Knight, Julia A. (Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ; Ko, Yon-Dschun (Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus) ; Konstantopoulou, Irene (Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ; Kosma, Veli-Matti (School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ; Kristensen, Vessela (Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet) ; Kwong, Ava (Department of Surgery, The University of Hong Kong) ; Laitman, Yael (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ; Lambrechts, Diether (Vesalius Research Center, VIB) ; Lazaro, Conxi (Institut Català d'Oncologia) ; Lee, Eunjung (Department of Preventive Medicine, University of Southern California) ; Le Marchand, Loic (Cancer Epidemiology Program, University of Cancer Center) ; Lester, Jenny (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Lindblom, Annika (Karolinska Institutet (Estocolm, Suècia). Department of Molecular Medicine and Surgery) ; Lindor, Noralane (Health Sciences Research, Mayo Clinic) ; Lindstrom, Sara (Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health) ; Liu, Jianjun (Human Genetics Division, Genome Institute of Singapore) ; Long, Jirong (Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Lubinski, Jan (Department of Genetics and Pathology, Pomeranian Medical University) ; Mai, Phuong L. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ; Makalic, Enes (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Malone, Kathleen E. (Department of Epidemiology, School of Public Health and Community Medicine, University of Washington) ; Mannermaa, Arto (School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ; Manoukian, Siranoush (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ; Margolin, Sara (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Marme, Frederik (Department of Obstetrics and Gynecology, University of Heidelberg) ; Martens, John W. M. (Department of Medical Oncology, Erasmus MC Cancer Institute) ; McGuffog, Lesley (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Meindl, Alfons (Department of Gynaecology and Obstetrics, Technical University of Munich) ; Miller, Austin (NRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute) ; Milne, Roger L. (Cancer Epidemiology Centre (Melbourne, Austràlia)) ; Miron, Penelope (Department of Genomics and Genome Sciences, Case Western Reserve University Medical School) ; Montagna, Marco (Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS) ; Mazoyer, Sylvie (INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon) ; Mulligan, Anna M. (Department of Laboratory Medicine and Pathobiology, University of Toronto) ; Muranen, Taru A. (Helsinki University Central Hospital) ; Nathanson, Katherine L. (Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania) ; Neuhausen, Susan L. (Department of Population Sciences, Beckman Research Institute of City of Hope) ; Nevanlinna, Heli (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ; Nordestgaard, Børge G. (Copenhagen University Hospital) ; Nussbaum, Robert L. (Invitae Corporation) ; Offit, Kenneth (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ; Olah, Edith (Department of Molecular Genetics, National Institute of Oncology) ; Olopade, Olufunmilayo I. (Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center) ; Olson, Janet E. (Department of Health Sciences Research, Mayo Clinic) ; Osorio, Ana (Centro Nacional de Investigaciones Oncológicas) ; Park, Sue K. (Department of Preventive Medicine and Biomedical Science, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University) ; Peeters, Petra H. (MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London) ; Peissel, Bernard (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ; Peterlongo, Paolo (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare) ; Peto, Julian (Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine) ; Phelan, Catherine M. (Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute) ; Pilarski, Robert (Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University) ; Poppe, Bruce (Center for Medical Genetics, Ghent University) ; Pylkäs, Katri (Oulu University Hospital (Finlàndia)) ; Radice, Paolo (Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ; Rahman, Nazneen (Section of Cancer Genetics, Institute of Cancer Research) ; Rantala, Johanna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Rappaport, Christine (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ; Rennert, Gad (Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine) ; Richardson, Andrea (Department of Pathology, Johns Hopkins University School of Medicine) ; Robson, Mark (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ; Romieu, Isabelle (International Agency for Research on Cancer) ; Rudolph, Anja (Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)) ; Rutgers, Emiel J. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ; Sanchez, Maria-Jose (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Santella, Regina M. (Department of Environmental Health Sciences, Columbia University) ; Sawyer, Elinor J. (Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital) ; Schmidt, Daniel F. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Schmidt, Marjanka K. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ; Schmutzler, Rita K. (Center for Molecular Medicine Cologne (CMMC), University of Cologne) ; Schumacher, Fredrick (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Scott, Rodney (Division of Genetics, Hunter Area Pathology Service, John Hunter Hospital) ; Senter, Leigha (Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University) ; Sharma, Priyanka (Department of Hematology and Oncology, University of Kansas Medical Center) ; Simard, Jacques (Centre Hospitalier Universitaire de Québec Research Center, Laval University) ; Singer, Christian F. (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ; Sinilnikova, Olga M. (Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard) ; Soucy, Penny (Centre Hospitalier Universitaire de Québec Research Center, Laval University) ; Southey, Melissa (Department of Pathology, The University of Melbourne) ; Steinemann, Doris (Hannover Medical School) ; Stenmark-Askmalm, Marie (Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University) ; Stoppa-Lyonnet, Dominique (Université Paris Descartes) ; Swerdlow, Anthony (Division of Genetics and Epidemiology, Institute of Cancer Research) ; Szabo, Csilla I. (National Human Genome Research Institute, National Institutes of Health) ; Tamimi, Rulla (Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health) ; Tapper, William (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ; Teixeira, Manuel R. (Biomedical Sciences Institute (ICBAS), Porto University) ; Teo, Soo-Hwang (University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya) ; Terry, Mary Beth (Department of Epidemiology, Mailman School of Public Health, Columbia University) ; Thomassen, Mads (Odense University Hospital (Dinamarca)) ; Thompson, Deborah (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Tihomirova, Laima (Latvian Biomedical Research and Study Centre) ; Toland, Amanda E. (Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University) ; Tollenaar, Robert A. E. M. (Department of Surgical Oncology, Leiden University Medical Center) ; Tomlinson, Ian (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Truong, Thérèse (Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer) ; Tsimiklis, Helen (Department of Pathology, The University of Melbourne) ; Teulé, Alex (Institut d'Investigació Biomèdica de Bellvitge) ; Tumino, Rosario (Cancer Registry and Histopathology Unit, 'Civic-M.P. Arezzo' Hospital) ; Tung, Nadine (Department of Medical Oncology, Beth Israel Deaconess Medical Center) ; Turnbull, Clare (Section of Cancer Genetics, Institute of Cancer Research) ; Ursin, Giski (Cancer Registry of Norway, Institute of Population-Based Cancer Research) ; van Deurzen, Carolien H. M. (Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center) ; van Rensburg, Elizabeth J. (Department of Genetics, University of Pretoria) ; Varon-Mateeva, Raymonda (Institute of Human Genetics, Charite Berlin) ; Wang, Zhaoming (Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Wang-Gohrke, Shan (University Hospital of Ulm (Alemanya)) ; Weiderpass, Elisabete (Genetic Epidemiology Group, Folkhälsan Research Center) ; Weitzel, Jeffrey N. (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ; Whittemore, Alice (Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine) ; Wildiers, Hans (Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals) ; Winqvist, Robert (Oulu University Hospital (Finlàndia)) ; Yang, Xiaohong R. (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Yannoukakos, Drakoulis (Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ; Yao, Song (Department of Cancer Prevention and Control, Roswell Park Cancer Institute) ; Zamora, M. Pilar (Hospital Universitario La Paz (Madrid)) ; Zheng, Wei (Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Hall, Per (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Kraft, Peter (Department of Biostatistics, Harvard School Of Public Health) ; Vachon, Celine (Department of Health Sciences Research, Mayo Clinic) ; Slager, Susan (Department of Health Sciences Research, Mayo Clinic) ; Chenevix-Trench, Georgia (Cancer Division, QIMR Berghofer Medical Research Institute) ; Pharoah, Paul D. P. (Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge) ; Monteiro, Alvaro A. N. (Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute) ; García-Closas, Montserrat (Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ; Easton, Douglas F. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Antoniou, Antonis C. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Universitat Autònoma de Barcelona
Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P <5 × 10 −8) with oestrogen receptor (ER)-negative breast cancer and BRCA1 -associated breast cancer risk. [...]
2016 - 10.1038/ncomms11375
Nature communications, Vol. 7 (04 2016)  

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