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9 p, 419.0 KB |
Transmission of HIV drug resistance and the predicted effect on current first-line regimens in Europe
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Hofstra, L.M. (University Medical Center Utrecht) ;
Sauvageot, N. ;
Albert, J. ;
Alexiev, I. ;
Garcia, F. ;
Struck, D. ;
Van De Vijver, D.A.M.C. ;
Åsjö, B. ;
Beshkov, D. ;
Coughlan, S. ;
Descamps, D. ;
Griskevicius, A. ;
Hamouda, O. ;
Horban, A. ;
Van Kasteren, M. ;
Kolupajeva, T. ;
Kostrikis, L.G. ;
Liitsola, K. ;
Linka, M. ;
Mor, O. ;
Nielsen, C. ;
Otelea, D. ;
Paraskevis, D. ;
Paredes, R. ;
Puchhammer-Stöckl, E. (Medical University Vienna) ;
Sönnerborg, A. ;
Staneková, D. (Slovak Medical University) ;
Stanojevic, M. (University of Belgrade) ;
Van Laethem, K. ;
Zazzi, M. ;
Lepej, S.Z. ;
Boucher, C.A.B. ;
Schmit, J.C. ;
Wensing, A.M.J. ;
Puchhammer-Stockl, E. ;
Sarcletti, M. ;
Schmied, B. ;
Geit, M. ;
Balluch, G. ;
Vandamme, A. M. ;
Vercauteren, J. ;
Derdelinckx, I. ;
Sasse, A. ;
Bogaert, M. ;
Ceunen, H. ;
De Roo, A. ;
De Wit, S. ;
Echahidi, F. ;
Fransen, K. ;
Goffard, J.C. ;
Goubau, P. ;
Goudeseune, E. ;
Yombi, J.C. ;
Lacor, P. ;
Liesnard, C. ;
Moutschen, M. ;
Pierard, D. ;
Rens, R. ;
Schrooten, Y. ;
Vaira, D. ;
Vandekerckhove, L.P.R. ;
Van Den Heuvel, A. ;
Van Der Gucht, B. ;
Van Ranst, M. ;
Van Wijngaerden, E. ;
Vandercam, B. ;
Vekemans, M. ;
Verhofstede, C. ;
Clumeck, N. ;
Begovac, J. ;
Demetriades, I. ;
Kousiappa, I. ;
Demetriou, V. ;
Hezka, J. ;
Maly, M. ;
Machala, L. ;
Jørgensen, L.B. ;
Gerstoft, J. ;
Mathiesen, L. ;
Pedersen, C. ;
Nielsen, H. ;
Laursen, A. ;
Kvinesdal, B. ;
Ristola, M. ;
Suni, J. ;
Sutinen, J. ;
Assoumou, L. ;
Castor, G. ;
Grude, M. ;
Flandre, P. ;
Storto, A. ;
Kücherer, C. ;
Berg, T. ;
Braun, P. ;
Poggensee, G. ;
Däumer, M. ;
Eberle, J. ;
Heiken, H. ;
Kaiser, R. ;
Knechten, H. ;
Korn, K. ;
Müller, H. ;
Neifer, S. ;
Schmidt, B. ;
Walter, H. ;
Gunsenheimer-Bartmeyer, B. ;
Harrer, T. ;
Hatzakis, A. ;
Zavitsanou, A. ;
Vassilakis, A. ;
Lazanas, M. ;
Chini, M. ;
Lioni, A. ;
Sakka, V. ;
Kourkounti, S. ;
Paparizos, V. ;
Antoniadou, A. ;
Papadopoulos, A. ;
Poulakou, G. ;
Katsarolis, I. ;
Protopapas, K. ;
Chryssos, G. ;
Drimis, S. ;
Gargalianos, P. ;
Xylomenos, G. ;
Lourida, G. ;
Psichogiou, M. ;
Daikos, G.L. ;
Sipsas, N.V. ;
Kontos, A. ;
Gamaletsou, M.N. ;
Koratzanis, G. ;
Sambatakou, E. ;
Mariolis, H. ;
Skoutelis, A. ;
Papastamopoulos, V. ;
Georgiou, O. ;
Panagopoulos, P. ;
Maltezos, E. ;
De Gascun, C. ;
Byrne, C. ;
Duffy, M. ;
Bergin, C. ;
Reidy, D. ;
Farrell, G. ;
Lambert, Jo ;
O'Connor, E. ;
Rochford, A. ;
Low, J. ;
Coakely, P. ;
O'Dea, S. ;
Hall, W. ;
Levi, I. ;
Chemtob, D. ;
Grossman, Z. ;
De Luca, A. ;
Balotta, C. ;
Riva, C. ;
Mussini, C. ;
Caramma, I. ;
Capetti, A. ;
Colombo, M.C. ;
Rossi, C. ;
Prati, F. ;
Tramuto, F. ;
Vitale, F. ;
Ciccozzi, M. ;
Angarano, G. ;
Rezza, G. ;
Vasins, O. ;
Lipnickiene, V. ;
Hemmer, R. ;
Arendt, V. ;
Michaux, C. ;
Staub, T. ;
Sequin-Devaux, C. ;
Van Kessel, A. ;
Van Bentum, P.H.M. ;
Brinkman, K. ;
Connell, B.J. ;
Van Der Ende, M.E. ;
Hoepelman, I.M. ;
Kuipers, M. ;
Langebeek, N. ;
Richter, C. ;
Santegoets, R.M.W.J. ;
Schrijnders-Gudde, L. ;
Schuurman, R. ;
Van De Ven, B.J.M. ;
Kran, A.M.B. ;
Ormaasen, V. ;
Aavitsland, P. ;
Stanczak, J.J. ;
Stanczak, G.P. ;
Firlag-Burkacka, E. ;
Wiercinska-Drapalo, A. ;
Jablonowska, E. ;
Maolepsza, E. ;
Leszczyszyn-Pynka, M. ;
Szata, W. ;
Camacho, R. ;
Palma, C. ;
Borges, F. ;
Paixão, T. ;
Duque, V. ;
Araújo, F. ;
Paraschiv, S. ;
Tudor, A.M. ;
Cernat, R. ;
Chiriac, C. ;
Dumitrescu, F. ;
Prisecariu, L.J. ;
Jevtovic, D. ;
Salemovic, D. ;
Stanekova, D. ;
Habekova, M. ;
Chabadová, Z. ;
Drobkova, T. ;
Bukovinova, P. ;
Shunnar, A. ;
Truska, P. ;
Lunar, M. ;
Babic, D. ;
Tomazic, J. ;
Vidmar, L. ;
Vovko, T. ;
Karner, P. ;
Monge, S. ;
Moreno, S. ;
Del Amo, J. ;
Asensi, V. ;
Sirvent, J.L. ;
De Mendoza, C. ;
Delgado, Raquel (Institut d'Investigació Biomèdica Sant Pau) ;
Gutiérrez, F. ;
Berenguer, J. ;
Garcia-Bujalance, S. ;
Stella, N. ;
De Los Santos, I. ;
Blanco, J.R. ;
Dalmau, D. ;
Rivero, M. ;
Segura, F. ;
Elías, M.J.P. ;
Álvarez, Mar ;
Chueca, N. ;
Rodríguez-Martín, C. ;
Vidal, C. ;
Palomares, J.C. ;
Viciana, I. ;
Viciana, P. ;
Cordoba, J. ;
Aguilera, A. ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Galindo, M.J. ;
Miralles, C. ;
Del Pozo, M.A. ;
Ribera, E. ;
Iribarren, J.A. ;
Ruiz, L. ;
De La Torre, J. ;
Vidal, F. ;
Clotet Sala, Bonaventura ;
Heidarian, A. ;
Aperia-Peipke, K. ;
Axelsson, M. ;
Mild, M. ;
Karlsson, A. ;
Thalme, A. ;
Naver, Lars ;
Bratt, G. ;
Blaxhult, A. ;
Gisslén, M. ;
Svennerholm, B. ;
Björkman, P. ;
Säll, C. ;
Mellgren, None ;
Lindholm, A. ;
Kuylenstierna, N. ;
Montelius, R. ;
Azimi, F. ;
Johansson, B. ;
Carlsson, M. ;
Johansson, E. ;
Ljungberg, B. ;
Ekvall, H. ;
Strand, A. ;
Mäkitalo, S. ;
Öberg, S. ;
Holmblad, P. ;
Höfer, M. ;
Holmberg, H. ;
Josefson, P. ;
Ryding, U. ;
Bergbrant, I. ;
Universitat Autònoma de Barcelona
Numerous studies have shown that baseline drug resistance patterns may influence the outcome of antiretroviral therapy. Therefore, guidelines recommend drug resistance testing to guide the choice of initial regimen. [...]
2016 -  10.1093/cid/civ963
Clinical Infectious Diseases, Vol. 62 Núm. 5 (january 2016) , p. 655-663
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Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer
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Klein, Alison P. (Johns Hopkins School of Medicine, Baltimore, USA) ;
Wolpin, Brian M. (Dana-Farber Cancer Institute, Boston, USA) ;
Risch, Harvey A. (Yale School of Public Health, New Haven, USA) ;
Stolzenberg-Solomon, Rachael Z. (National Institutes of Health, Bethesda, USA) ;
Mocci, Evelina (Johns Hopkins School of Medicine, Baltimore, USA) ;
Zhang, Mingfeng (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Canzian, Federico (Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Childs, Erica J. (Johns Hopkins School of Medicine, Baltimore, USA) ;
Hoskins, Jason W. (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Jermusyk, Ashley (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Zhong, Jun (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Chen, Fei (Johns Hopkins School of Medicine, Baltimore, USA) ;
Albanes, Demetrius (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Andreotti, Gabriella (National Institutes of Health, Bethesda, USA) ;
Arslan, Alan A. (New York University School of Medicine, New York, USA) ;
Babic, Ana (Dana-Farber Cancer Institute, Boston, USA) ;
Bamlet, William R. (Mayo Clinic College of Medicine, Rochester, USA) ;
Beane-Freeman, Laura (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Berndt, Sonja (National Institutes of Health, Bethesda, USA) ;
Blackford, Amanda (Johns Hopkins School of Medicine, Baltimore, USA) ;
Borges, Michael (Johns Hopkins School of Medicine, Baltimore, USA) ;
Borgida, Ayelet (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, M5G 1×5, Canada.) ;
Bracci, Paige M. (University of California, San Francisco, USA) ;
Brais, Lauren (Dana-Farber Cancer Institute, Boston, USA) ;
Brennan, Paul (International Agency for Research on Cancer (IARC), Lyon, France) ;
Brenner, Hermann (Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Bueno-de-Mesquita, Bas (National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands) ;
Buring, Julie (righam and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Campa, Daniele (University of Pisa) ;
Capurso, Gabriele (University of Rome) ;
Cavestro, Giulia Martina (Vita-Salute San Raffaele University, Milan) ;
Chaffee, Kari G (Mayo Clinic College of Medicine, Rochester, USA) ;
Chung, Charles C. (National Institutes of Health, Bethesda, USA) ;
Cleary, Sean (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ;
Cotterchio, Michelle (University of Toronto.) ;
Dijk, Frederike (University of Amsterdam. Department of Pathology, Academic Medical Center) ;
Duell, Eric J. (Institut d'Investigació Biomèdica de Bellvitge) ;
Foretova, Lenka (Masaryk Memorial Cancer Institute. Department of Cancer Epidemiology and Genetics, Brno, Czech Republic.) ;
Fuchs, Charles (Yale Cancer Center, New Haven, USA) ;
Funel, Niccola (University of Pisa.) ;
Gallinger, Steven (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ;
M. Gaziano, J. Michael (Boston VA Healthcare System) ;
Gazouli, Maria (National and Kapodistrian University of Athens) ;
Giles, Graham G. (Monash University. Department of Epidemiology and Preventive Medicine, Melbourne, Australia) ;
Giovannucci, Edward (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Goggins, Michael (Johns Hopkins School of Medicine. Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Baltimore) ;
Goodman, Gary E. (Fred Hutchinson Cancer Research Center. Division of Public Health Sciences, Seattle, USA) ;
Goodman, Phyllis J. (Fred Hutchinson Cancer Research Center. SWOG Statistical Center, Seattle, USA) ;
Hackert, Thilo (University Hospital Heidelberg, Germany) ;
Haiman, Christopher A (University of Southern California, USA) ;
Hartge, Patricia (National Institutes of Health, Bethesda, USA) ;
Hasan, Manal (University of Texas MD Anderson Cancer Center, USA) ;
Hegyi, Peter (University of Szeged, Szeged, Hungary) ;
Helzlsouer, Kathy J. (National Institutes of Health, Bethesda, USA) ;
Herman, Joseph (Johns Hopkins School of Medicine. Baltimore, USA) ;
Holcatova, Ivana (Charles University, Prague, Czech Republic) ;
Holly, Elizabeth A. (University of California, San Francisco) ;
Hoover, Robert (National Institutes of Health, Bethesda, USA) ;
Hung, Rayjean J. (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ;
Jacobs, Eric J. (American Cancer Society. Epidemiology Research Program, Atlanta) ;
Jamroziak, Krzysztof (Institute of Hematology and Transfusion Medicine, Warsaw, Poland) ;
Janout, Vladimir (Faculty of Medicine, University of Olomouc, Czech Republic) ;
Kaaks, Rudolf (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Khaw, Kay-Tee (University of Cambridge) ;
Klein, Eric A. (Cleveland Clinic) ;
Kogevinas, M (Hospital del Mar (Barcelona, Catalunya)) ;
Kooperberg, Charles (Fred Hutchinson Cancer Research Center, Seattle) ;
Kulke, Matthew H. (Dana-Farber Cancer Institute, Boston) ;
Kupcinskas, Juozas (Lithuanian University of Health Sciences, Kaunas, Lithuania) ;
Kurtz, Robert J. (Memorial Sloan Kettering Cancer Center, New York, USA) ;
Laheru, Daniel (Johns Hopkins School of Medicine, Baltimore, USA) ;
Landi, Stefano (University of Pisa) ;
Lawlor, Rita T. (University and Hospital Trust of Verona) ;
Lee, I.-Min (Harvard School of Public Health, Boston) ;
LeMarchand, Loic (University of Hawaii Cancer Center, Honolulu, USA) ;
Lu, Lingeng (Yale School of Public Health, New Haven, USA) ;
Malats, Núria (Centro de Investigación Biomédica en Red de Cáncer, Madrid) ;
Mambrini, Andrea (Oncology Department, ASL1 Massa Carrara, Italy) ;
Männistö, Satu (National Institute for Health and Welfare, Helsinki, Finland) ;
Milne, Roger L. (The University of Melbourne, Australia) ;
Mohelníková-Duchoňová, Beatrice (Palacky University Olomouc and University Hospital, Czech Republic) ;
Neale, Rachel E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Neoptolemos, John P. (University of Heidelburg, Heidelberg, Germany) ;
Oberg, Ann L. (Mayo Clinic College of Medicine, Rochester, USA) ;
Olson, Sara H. (Memorial Sloan Kettering Cancer Center, New York, USA) ;
Orlow, Irene (Memorial Sloan Kettering Cancer Center, New York, USA) ;
Pasquali, Claudio (University of Padua, Italy) ;
Patel, Alpa V. (American Cancer Society, Atlanta) ;
Peters, Ulrike (Fred Hutchinson Cancer Research Center, Seattle) ;
Pezzilli, Raffaele (Sant'Orsola-Malpighi Hospital, Bologna, Italy) ;
Porta, Miquel 1957- (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Real, Francisco X. (Universitat Pompeu Fabra) ;
Rothman, Nathaniel (National Institutes of Health, Bethesda, USA) ;
Scelo, Ghislaine (International Agency for Research on Cancer (IARC), Lyon, France) ;
Sesso, Howard D. (Harvard T.H. Chan School of Public Health. Department of Epidemiology) ;
Severi, Gianluca (Université Paris-Saclay, France) ;
Shu, Xiao-Ou (Vanderbilt University School of Medicine, Nashville, USA) ;
Silverman, Debra (National Institutes of Health, Bethesda, USA) ;
Smith, Jill P. (Georgetown University, Washington, USA) ;
Soucek, Pavel (Charles University, Pilsen, Czech Republic.) ;
Sund, Malin (Umeå University, Sweden) ;
Talar-Wojnarowska, Renata (Medical University of Łodz, Poland) ;
Tavano, Francesca (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Italy) ;
Thornquist, Mark D. (Fred Hutchinson Cancer Research Center, Seattle) ;
Tobias, Geoffrey S. (National Institutes of Health, Bethesda, USA) ;
Van Den Eeden, Stephen K. (Kaiser Permanente Northern California, USA) ;
Vashist, Yogesh (University Hamburg-Eppendorf, Germany) ;
Visvanathan, Kala (Johns Hopkins Bloomberg School of Public Health, Baltimore, USA) ;
Vodicka, Pavel (Academy of Sciences of the Czech Republic, Prague, Czech Republic) ;
Wactawski-Wende, Jean (University at Buffalo, USA) ;
Wang, Zhaoming (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ;
Wentzensen, Nicolas (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
White, Emily (University of Washington, USA) ;
Yu, Herbert (University of Hawaii Cancer Center, USA) ;
Yu, Kai (National Institutes of Health, Bethesda, USA) ;
Zeleniuch-Jacquotte, Anne (New York University School of Medicine, USA) ;
Zheng, Wei (Vanderbilt University School of Medicine, Nashville, USA) ;
Kraft, Peter (Harvard School of Public Health, USA) ;
Li, Donghui (University of Texas MD Anderson Cancer Center, USA) ;
Chanock, Stephen (National Institutes of Health, Bethesda, USA) ;
Obazee, Ofure (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Petersen, Gloria M. (Mayo Clinic College of Medicine, Rochester, USA) ;
Amundadottir, Laufey T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica))
In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe and the United States combined. To identify common susceptibility alleles, we performed the largest pancreatic cancer GWAS to date, including 9040 patients and 12,496 controls of European ancestry from the Pancreatic Cancer Cohort Consortium (PanScan) and the Pancreatic Cancer Case-Control Consortium (PanC4). [...]
2018 - 10.1038/s41467-018-02942-5
Nature communications, Vol. 9 (february 2018)
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