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11 p, 691.7 KB |
The Relationship Between Grey Matter Volume and Clinical and Functional Outcomes in People at Clinical High Risk for Psychosis
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Tognin, Stefania ;
Richter, Anja ;
Kempton, Matthew J ;
Modinos, Gemma ;
Antoniades, Mathilde ;
Azis, Matilda ;
Allen, Paul ;
Bossong, Matthijs G ;
Perez, Jesus ;
Pantelis, Christos ;
Nelson, Barnaby ;
Amminger, Paul ;
Riecher-Rössler, Anita ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Krebs, Marie-Odile ;
Glenthøj, Birte ;
Ruhrmann, Stephan ;
Sachs, Gabriele ;
Rutten, Bart P. F. ;
de Haan, Lieuwe ;
van der Gaag, Mark ;
Valmaggia, Lucia ;
McGuire, Philip
To examine the association between baseline alterations in grey matter volume (GMV) and clinical and functional outcomes in people at clinical high risk (CHR) for psychosis. 265 CHR individuals and 92 healthy controls were recruited as part of a prospective multi-center study. [...]
2022 - 10.1093/schizbullopen/sgac040
Schizophrenia Bulletin Open, Vol. 3 (june 2022)
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11 p, 1.7 MB |
Regional grey matter microstructural changes and volume loss according to disease duration in multiple sclerosis patients
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Solana, E. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martinez-Heras, E. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Vilaplana, E. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Lopez-Soley, E. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Radua, J. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Montejo, C. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Blanco, Yolanda (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pulido-Valdeolivas, I. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sepúlveda, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Andorra, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Berenguer, Juan (Hospital Clínic i Provincial de Barcelona) ;
Villoslada, P. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martinez-Lapiscina, E.H. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Prados, F. (NMR Research Unit. Queen Square MS Centre. Department of Neuroinflammation. UCL Institute of Neurology. University College London) ;
Saiz, A. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Llufriu, S. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
The spatio-temporal characteristics of grey matter (GM) impairment in multiple sclerosis (MS) are poorly understood. We used a new surface-based diffusion MRI processing tool to investigate regional modifications of microstructure, and we quantified volume loss in GM in a cohort of patients with MS classified into three groups according to disease duration. [...]
2021 - 10.1038/s41598-021-96132-x
Scientific reports, Vol. 11 Núm. 1 (december 2021) , p. 16805
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15 p, 1.0 MB |
Specific cortical and subcortical grey matter regions are associated with insomnia severity
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Falgàs, Neus (Hospital Clínic i Provincial de Barcelona) ;
Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Allen, Isabel (University of California San Francisco) ;
Mumford, Paige (University of California, San Francisco) ;
Essanaa, Youssef M. (University of California, San Francisco) ;
Le, Michael M. (University of California, San Francisco) ;
You, Michelle (University of California, San Francisco, California) ;
Grinberg, Lea T. (University of California, San Francisco) ;
Rosen, Howard J. (University of California, San Francisco) ;
Neylan, Thomas C. (San Francisco VA Medical Center) ;
Kramer, Joel H. (University of California, San Francisco) ;
Walsh, Christine M. (University of California, San Francisco, California) ;
Universitat Autònoma de Barcelona
There is an increasing awareness that sleep disturbances are a risk factor for dementia. Prior case-control studies suggested that brain grey matter (GM) changes involving cortical (i. e, prefrontal areas) and subcortical structures (i. [...]
2021 - 10.1371/journal.pone.0252076
PloS one, Vol. 16 (may 2021)
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6 p, 396.2 KB |
Gris es un color bonito
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Tena Parera, Daniel (Universitat Autònoma de Barcelona)
Alguien preguntó ¿porqué un galgo para el symposium grafica? En realidad, siempre hay alguien que pregunta por ello. Eso es una buena señal para el symposium grafica dado que es un indicio de su crecimiento. [...] Someone asked why a greyhound for the graphic symposium? Actually, there is always someone who asks about it. That is a good sign for the graphic symposium as it is an indication of its growth. The seventh graphic symposium has been held and we want to show that we make it possible together. [...]
2022 - 10.5565/rev/grafica.236
Grafica, Vol. 10 Núm. 19 (2022) , p. 5-09 (Opinión)
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8 p, 2.0 MB |
Development and evaluation of a manual segmentation protocol for deep grey matter in multiple sclerosis : Towards accelerated semi-automated references
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de Sitter, Alexandra (MS Center Amsterdam) ;
Burggraaff, Jessica (MS Center Amsterdam) ;
Bartel, Fabian (MS Center Amsterdam) ;
Palotai, Miklos (Harvard Medical School) ;
Liu, Yaou (MS Center Amsterdam) ;
Simoes, Jorge (MS Center Amsterdam) ;
Ruggieri, Serena (San Camillo Forlanini Hospital) ;
Schregel, Katharina (University Medical Center Goettingen) ;
Ropele, Stefan (Medical University of Graz) ;
Rocca, Maria A. (San Raffaele Scientific Institute) ;
Gasperini, Claudio (San Camillo Forlanini Hospital) ;
Gallo, Antonio (University of Campania "Luigi Vanvitelli", Naples) ;
Schoonheim, Menno M. (Amsterdam UMC) ;
Amann, Michael (University Hospital Basel (Basilea, Suïssa)) ;
Yiannakas, Marios (UCL Institute of Neurology (Regne Unit)) ;
Pareto, Deborah (Hospital Universitari Vall d'Hebron) ;
Wattjes, Mike P. (Hannover Medical School) ;
Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ;
Kappos, Ludwig (University Hospital Basel (Basilea, Suïssa)) ;
Filippi, Massimo (Vita-Salute San Raffaele University) ;
Enzinger, Christian (Medical University of Graz) ;
Frederiksen, Jette (Glostrup University Hospital Copenhagen) ;
Uitdehaag, Bernard (MS Center Amsterdam) ;
Guttmann, Charles R. G. (Harvard Medical School) ;
Barkhof, Frederik (Institutes of Neurology & Healthcare Engineering, London) ;
Vrenken, Hugo (Amsterdam UMC) ;
Universitat Autònoma de Barcelona
Deep grey matter (dGM) structures, particularly the thalamus, are clinically relevant in multiple sclerosis (MS). However, segmentation of dGM in MS is challenging; labeled MS-specific reference sets are needed for objective evaluation and training of new methods. [...]
2021 - 10.1016/j.nicl.2021.102659
NeuroImage, Vol. 30 (april 2021)
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13 p, 1.2 MB |
Progression of regional grey matter atrophy in multiple sclerosis
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Eshaghi, Arman (University College London. Department of Computer Science) ;
Marinescu, Razvan V (University College London. Department of Computer Science) ;
Young, Alexandra L. (University College London. Department of Computer Science) ;
Firth, Nicholas C. (University College London. Department of Computer Science) ;
Prados Carrasco, Ferran (University College London. Department of Medical Physics and Bioengineering) ;
Jorge Cardoso, M. (University College London. Department of Medical Physics and Bioengineering) ;
Tur, Carmen (University College London. Faculty of Brain Sciences) ;
De Angelis, Floriana (University College London. Faculty of Brain Sciences) ;
Cawley, Niamh (University College London. Faculty of Brain Sciences) ;
Brownlee, Wallace J. (University College London. Faculty of Brain Sciences) ;
De Stefano, Nicola (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ;
Laura Stromillo, M. (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ;
Battaglini, Marco (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ;
Ruggieri, Serena (University of Rome Sapienza. Department of Neurology and Psychiatry) ;
Gasperini, Claudio (San Camillo Forlanini Hospital) ;
Filippi, Massimo (Vita-Salute San Raffaele University (Milà, Itàlia)) ;
Rocca, Maria A. (Vita-Salute San Raffaele University (Milà, Itàlia)) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron) ;
Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Geurts, Jeroen J. G. (Amsterdam UMC. University Medical Center) ;
Vrenken, Hugo (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Wottschel, Viktor (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Leurs, Cyra E. (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Uitdehaag, Bernard (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Pirpamer, Lukas (Medical University of Graz (Graz, Àustria)) ;
Enzinger, Christian (Medical University of Graz (Graz, Àustria)) ;
Ourselin, Sebastien (University College London Hospitals) ;
Gandini Wheeler-Kingshott, Claudia A. M (IRCCS Mondino Foundation (Pavia, Itàlia)) ;
Chard, Declan (University College London Hospitals) ;
Thompson, Alan J. (University College London. Faculty of Brain Sciences) ;
Barkhof, Frederik (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Alexander, Daniel C.. (University College London. Department of Computer Science) ;
Ciccarelli, Olga (University College London Hospitals) ;
Universitat Autònoma de Barcelona
See Stankoff and Louapre (doi:) for a scientific commentary on this article. Grey matter atrophy in multiple sclerosis affects certain areas preferentially. Eshaghi et al. use a data-driven computational model to predict the order in which regions atrophy, and use this sequence to stage patients. [...]
2018 - 10.1093/brain/awy088
Brain, Vol. 141 (may 2018) , p. 1665-1677
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14 p, 1.7 MB |
Reduced accuracy of MRI deep grey matter segmentation in multiple sclerosis : an evaluation of four automated methods against manual reference segmentations in a multi-center cohort
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de Sitter, Alexandra (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Verhoeven, Tom (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Burggraaff, Jessica (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Neurology, MS Center Amsterdam) ;
Liu, Yaou (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Simoes, Jorge (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Ruggieri, Serena (San Camillo Forlanini Hospital) ;
Palotai, Miklos (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Brouwer, Iman (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Versteeg, Adriaan (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Wottschel, Viktor (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Ropele, Stefan (Medical University of Graz. Department of Neurology) ;
Rocca, Mara A. (IRCCS San Raffaele Scientific Institute (Milà, Itàlia). Neurology Unit) ;
Gasperini, Claudio (San Camillo Forlanini Hospital) ;
Gallo, Antonio (University of Campania "Luigi Vanvitelli". Division of Neurology and MRI Research Center, Department of Medical, Surgical, Neurologic, Metabolic and Aging Sciences) ;
Yiannakas, Marios C. (University College London. Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Enzinger, Christian (University of Graz. Division of Neuroradiology, Vascular and Interventional Radiology, Department of Radiology Medical) ;
Filippi, Massimo (Vita-Salute San Raffaele University) ;
De Stefano, Nicola (University of Siena. Department of Neurological and Behavioural Sciences) ;
Kappos, Ludwig (University Hospital, Kantonsspital. Department of Neurology) ;
Frederiksen, Jette L. (Glostrup University Hospital Copenhagen) ;
Uitdehaag, Bernard M. J. (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Neurology, MS Center Amsterdam) ;
Barkhof, Frederik (University College London. Institutes of Neurology & Healthcare Engineering) ;
Guttmann, Charles R. G. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Vrenken, Hugo (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ;
Universitat Autònoma de Barcelona
Deep grey matter (DGM) atrophy in multiple sclerosis (MS) and its relation to cognitive and clinical decline requires accurate measurements. MS pathology may deteriorate the performance of automated segmentation methods. [...]
2020 - 10.1007/s00415-020-10023-1
Journal of Neurology, Vol. 267 (july 2020) , p. 3541-3554
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14 p, 6.6 MB |
From Mouse To Human : Comparative Analysis Between Grey And White Matter By Synchrotron-Fourier Transformed Infrared Microspectroscopy
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Sanchez-Molina, Paula (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Valente, Tony (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Almolda Ardid, Beatriz (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
González, Berta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Castellano López, Bernardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Peralvarez-Marin, Alex (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Kreuzer, Martin (ALBA Laboratori de Llum de Sincrotró) ;
Benseny Cases, Núria (ALBA Laboratori de Llum de Sincrotró)
Fourier Transform Infrared microspectroscopy (μFTIR) is a very useful method to analyze the biochemical properties of biological samples in situ. Many diseases affecting the central nervous system (CNS) have been studied using this method, to elucidate alterations in lipid oxidation or protein aggregation, among others. [...]
2020 - 10.3390/biom10081099
Biomolecules, Vol. 10, Núm. 8 (August 2020) , art. 1099
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