Web of Science: 25 cites, Scopus: 32 cites, Google Scholar: cites,
Psychopathological symptoms associated with synthetic cannabinoid use : a comparison with natural cannabis
Mensen, Vincent T. (Department of Drug Monitoring (Utrecht, Països Baixos))
Vreeker, Annabel (University of Utrecht. University Medical Center Utrecht, Department of Psychiatry)
Nordgren, Johan (Malmö University. Department of Social Work)
Atkinson, Amanda (Liverpool John Moores University. Public Health Institute)
De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques)
Farré Albaladejo, Magí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Ramaekers, Johannes G. (Maastricht University. Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience)
Brunt, Tibor M. (Radboud University. Department of Developmental Psychopathology)
Universitat Autònoma de Barcelona

Data: 2019
Resum: Synthetic cannabinoids (SCs) are a class of new psychoactive substances that have been rapidly evolving around the world throughout recent years. Many different synthetic cannabinoid analogues are on the consumer market and sold under misleading names, like "spice" or "incense. " A limited number of studies have reported serious health effects associated with SC use. In this study, we compared clinical and subclinical psychopathological symptoms associated with SC use and natural cannabis (NC) use. A convenience sample of 367 NC and SC users was recruited online, including four validated psychometric questionnaires: The Drug Use Disorders Identification Test (DUDIT), Insomnia Severity Index (ISI), Altman Mania Scale (Altman), and Brief Symptom Inventory (BSI). The two groups were compared with analysis of variance (ANOVA) and covariance (ANCOVA), chi 2 tests, and logistic regression when appropriate. The SC user group did not differ in age from the NC user group (27. 7 years), but contained less females (21% and 30%, respectively). SC users scored higher than NC users on all used psychometric measures, indicating a higher likelihood of drug abuse, sleep problems, (hypo)manic symptoms, and the nine dimensions comprising the BSI, somatization, obsessive-compulsive behavior, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, and psychoticism. Odds ratios (95% CI) for the SC user group vs NC user group were, respectively, drug dependence 3. 56 (1. 77-7. 16), (severe) insomnia 5. 01 (2. 10-11. 92), (hypo-)mania 5. 18 (2. 04-13. 14), and BSI psychopathology 5. 21 (2. 96-9. 17). This study shows that SC use is associated with increased mental health symptomatology compared to NC use.
Ajuts: Instituto de Salud Carlos III PI14-00715
Nota: Altres ajuts: This study was funded by the European Commission (Drugs Policy Initiatives, Justice Programme 2014-2020, contract no. HOME/2014/JDRU/AG/DRUG/7082, Predicting Risk of Emerging Drugs With In Silico and Clinical Toxicology, PREDICT project).
Drets: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Llengua: Anglès
Document: Article ; recerca ; Versió publicada
Matèria: Cannabis ; Synthetic cannabis ; Spice ; Mental health ; Psychology ; Psychiatry ; Questionnaire ; BSI ; ISI ; Altman ; DUDIT
Publicat a: Psychopharmacology, Vol. 236 (april 2019) , p. 2677-2685, ISSN 1432-2072

DOI: 10.1007/s00213-019-05238-8
PMID: 30968175


9 p, 287.3 KB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Articles de recerca
Articles > Articles publicats

 Registre creat el 2020-07-06, darrera modificació el 2025-10-01



   Favorit i Compartir