Interaction of heart failure and stroke : A clinical consensus statement of the ESC Council on Stroke, the Heart Failure Association (HFA) and the ESC Working Group on Thrombosis
Doehner, Wolfram (Charité-Universitätsmedizin Berlin)
Böhm, Michael (Universitätsklinikum des Saarlandes)
Boriani, Giuseppe (University of Modena and Reggio Emilia)
Christersson, Christina (Uppsala University)
Coats, Andrew Justin Stewart (Heart Research Institute)
Haeusler, Karl Georg (Universitätsklinikum Würzburg)
Jones, Ian D. (Liverpool John Moores University)
Lip, Gregory Y. H (Aalborg Universitet)
Metra, Marco (University of Brescia)
Ntaios, George (University of Thessaly (Grecia))
Savarese, Gianluigi (Karolinska Institutet (Estocolm, Suècia))
Shantsila, Eduard (University of Liverpool)
Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau)
Rosano, Giuseppe (St George's University Hospital)
Universitat Autònoma de Barcelona

Data:	2023
Resum:	Heart failure (HF) is a major disease in our society that often presents with multiple comorbidities with mutual interaction and aggravation. The comorbidity of HF and stroke is a high risk condition that requires particular attention to ensure early detection of complications, efficient diagnostic workup, close monitoring, and consequent treatment of the patient. The bi-directional interaction between the heart and the brain is inherent in the pathophysiology of HF where HF may be causal for acute cerebral injury, and - in turn - acute cerebral injury may induce or aggravate HF via imbalanced neural and neurovegetative control of cardiovascular regulation. The present document represents the consensus view of the ESC Council on Stroke, the Heart Failure Association and the ESC Working Group on Thrombosis to summarize current insights on pathophysiological interactions of the heart and the brain in the comorbidity of HF and stroke. Principal aspects of diagnostic workup, pathophysiological mechanisms, complications, clinical management in acute conditions and in long-term care of patients with the comorbidity are presented and state-of-the-art clinical management and current evidence from clinical trials is discussed. Beside the physicians perspective, also the patients values and preferences are taken into account. Interdisciplinary cooperation of cardiologists, stroke specialists, other specialists and primary care physicians is pivotal to ensure optimal treatment in acute events and in continued long-term treatment of these patients. Key consensus statements are presented in a concise overview on mechanistic insights, diagnostic workup, prevention and treatment to inform clinical acute and continued care of patients with the comorbidity of HF and stroke.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Cardiac reflex ; Cognition ; Heart failure ; Mood ; Muscle ; Stroke
Publicat a:	European Journal of Heart Failure, Vol. 25 Núm. 12 (december 2023) , p. 2107-2129, ISSN 1879-0844

DOI: 10.1002/ejhf.3071
PMID: 37905380

23 p, 2.2 MB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
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